Advances in flexible ionic thermal sensors: present and perspectives.

Ionic thermal sensors (ITSs) represent a promising frontier in sensing technology, offering unique advantages over conventional electronic sensors. Comprising a polymer matrix and electrolyte, these sensors possess inherent flexibility, stretchability, and biocompatibility, allowing them to establish stable and intimate contact with soft surfaces without inducing mechanical or thermal stress. Through an ion migration/dissociation mechanism similar to biosensing, ITSs ensure low impedance contact and high sensitivity, especially in physiological monitoring applications.

Eucommia ulmoides flavonoids alleviate intestinal oxidative stress damage in weaned piglets by regulating the Nrf2/Keap1 signaling pathway.

This study examined how Eucommia ulmoides flavonoids (EUF) protect against intestinal oxidative stress induced by deoxynivalenol (DON) in weaned piglets. Forty weaned piglets were randomly assigned to four dietary groups for a period of 14 days. The piglets were fed a control diet (Control) or the Control diet supplemented with 100 mg EUF/kg (EUF group), 4 mg DON/kg diet (DON group) or both (EUF+DON group) in a 2×2 factorial design.

Shallow defects and optical properties of CsPbBrthin films through noble gas ion beam defect engineering.

Ion implantation is widely utilised for the modification of inorganic semiconductors; however, the technique has not been extensively applied to lead halide perovskites. In this report, we demonstrate the modification of the optical properties of caesium lead bromide (CsPbBr) thin films via noble gas ion implantation. We observed that the photoluminescence (PL) lifetimes of CsPbBrthin films can be doubled by low fluences (<1 × 10at·cm) of ion implantation with an acceleration voltage of 20 keV.

Enhancing culturally responsive care in perioperative settings for older adult patients: A qualitative interview study.

Background: Older adults aged over 65 are increasingly admitted to hospital for acute care reasons, including surgical procedures. In multicultural societies, the diversity of an ageing population has significant implications for the planning and delivery of culturally responsive perioperative care for older adults from ethnically diverse backgrounds, who are admitted to hospital for surgical intervention.

Objective: To explore the perspectives and experiences of perioperative staff when caring for older adult patients from ethnically diverse backgrounds.

Stakeholders' perceptions of personal health data sharing: A scoping review.

The rapid advancement of digital health technologies has heightened demand for health data for secondary uses, highlighting the importance of understanding global perspectives on personal information sharing. This article examines stakeholder perceptions and attitudes toward the use of personal health data to improve personalized treatments, interventions, and research. It also identifies barriers and facilitators in health data sharing and pinpoints gaps in current research, aiming to inform ethical practices in healthcare settings that utilize digital technologies.

Hybrid plug-and-play CT image restoration using nonconvex low-rank group sparsity and deep denoiser priors.

. Low-dose computed tomography (LDCT) is an imaging technique that can effectively help patients reduce radiation dose, which has attracted increasing interest from researchers in the field of medical imaging. Nevertheless, LDCT imaging is often affected by a large amount of noise, making it difficult to clearly display subtle abnormalities or lesions.

Effect of a home-based exercise program on subsequent falls among community-dwelling older adults with cognitive frailty: A sub-group analysis of a randomized controlled trial.

Objectives: Cognitive frailty is characterized by concurrent physical frailty and mild cognitive impairment and is associated with increased risk of falls. Exercise is an evidence-based strategy to prevent falls, but whether exercise reduces falls in people with cognitive frailty is unknown. We examined the effects of home-based exercise on subsequent falls among community-dwelling older adults with cognitive frailty who have previously fallen.

Assessing momentary stress responses to dynamic real-time greenspace exposure: Unveiling algorithmic uncertainty and the temporality of exposure context.

Mental stress issues are emerging among residents of modern cities. Among environmental factors associated with stress mitigation, greenspace has consistently been shown to have significant stress-reducing properties. However, the temporality of greenspace exposure, particularly the cumulative threshold effect in urban environments, has been largely neglected in past studies.

Colorimetric Thermography by a Long-Infrared Dual-Band Metalens.

Infrared (IR) radiation thermography is extensively utilized in diverse fields due to its non-contact capability. Nevertheless, its effectiveness is often compromised by the significant emissivity variations among different objects, limiting its application to specific setups or focused object types. Colorimetric thermography is introduced as an alternative emissivity-independent method of radiation thermometry.

One Health and Oral Health: A Scoping Review to Inform Research and Present Challenges.

Background: "One health" is an integrated, unifying approach that recognizes the interconnectedness between the health of people, animals, and the environment. Oral diseases are the most common diseases to affect humankind, and it is increasingly acknowledged that key determinants of oral heath are social and environmental. However, there is a dearth of information on the relationship between oral health and one health.

Selective recognition of RNA G-quadruplex in vitro and in cells by L-aptamer-D-oligonucleotide conjugate.

RNA Guanine-quadruplexes (rG4s) are important nucleic acid structures that govern vital biological processes. Although numerous tools have been developed to target rG4s, few specific tools are capable of discerning individual rG4 of interest. Herein, we design and synthesize the first L-aptamer-antisense oligonucleotide (ASO) conjugate, L-Apt.

Cognitive functioning in people with psychotic experiences: a systematic review and meta-analysis study.

Earlier research suggested that psychotic experiences (PEs), the extended-psychosis phenotype, are associated with cognitive impairment. Recent studies, however, revealed more mixed findings, and patterns and magnitude of cognitive deficits in PEs remain uncertain. We aimed to systematically review and quantitatively synthesize estimates of cognitive functioning covering a wide array of domains in individuals with versus without PEs.

Polyinosinic/Polycytidylic Lipid Nanoparticles Enhance Immune Cell Infiltration and Improve Survival in the Glioblastoma Mouse Model.

Glioblastoma (GBM) immunotherapy is particularly challenging due to the pro-tumorigenic microenvironment, marked by low levels and inactive immune cells. Toll-like receptor (TLR) agonists have emerged as potent immune adjuvants but failed to show improved outcomes in clinical trials when administered as a monotherapy. We hypothesize that a combined nanoparticulate formulation of TLR agonist and immunogenic cell death-inducing drug (doxorubicin) will synergize to induce improved GBM immunotherapy.

Cross-population validation of the PreMO risk indicator for predicting myopia onset in children.

Purpose: The Predicting Myopia Onset and progression (PreMO) risk indicator, developed using data generated from white children in the UK, incorporates age, spherical equivalent refraction (SER), axial length (AL) and parental myopia to stratify the likelihood of developing myopia. This study evaluated the PreMO's predictive accuracy using prospective datasets from independent samples of children in Hong Kong (HK) and an ethnically diverse cohort of children in the United Kingdom.

Methods: Non-myopic children (SER > -0.

Advantages and feasibility of prefabricated PEEK crowns for aesthetic restoration in primary teeth.

Objectives The main purpose of this study is to evaluate the efficacy of polyetheretherketone (PEEK) as a material for prefabricated crown restorations in pediatric dentistry, particularly for restoring primary tooth structure defects. Materials and methods This study analyzed the effects of three surface treatment modalities on PEEK's surface morphology, wettability (as measured by contact angle), and shear bond strength. These treatments included alumina (AlO) sandblasting alone, and in conjunction with a 98% sulfuric acid pretreatment.

Development and validation of a clinical prediction tool to estimate survival in community-dwelling adults living with dementia: a protocol.

Introduction: A clinical prediction tool to estimate life expectancy in community-dwelling individuals living with dementia could inform healthcare decision-making and prompt future planning. An existing Ontario-based tool for community-dwelling elderly individuals does not perform well in people living with dementia specifically. This study seeks to develop and validate a clinical prediction tool to estimate survival in community-dwelling individuals living with dementia receiving home care in Ontario, Canada.

Bacillus cereus in rice: A review on food poisoning, antimicrobial resistance, and control measures.

Rice is often associated with Bacillus cereus (B. cereus) food poisoning. This review aims to explore the food poisoning activity, antimicrobial resistance, and control measures of B.

Effect of aspirin on biomarker profile in women at high risk for preeclampsia.

Background: There is limited evidence in the literature regarding the temporal changes of preeclampsia-related biomarkers during pregnancy in high-risk women who develop preeclampsia despite the administration of aspirin prophylaxis.

Objective: This study aimed to compare the temporal changes in mean arterial pressure, uterine artery pulsatility index, placental growth factor, and soluble fms-like tyrosine kinase-1 across gestation in women identified as having high risk for preterm preeclampsia receiving aspirin prophylaxis and low-risk women without aspirin treatment.

Study Design: This was a prospective longitudinal nested case-control study of 2007 women with singleton pregnancies who participated in the first-trimester screen-and-prevent program for preeclampsia at the Prince of Wales Hospital, Hong Kong Special Administrative Region, China, between January 2020 and May 2023.

Sodium butyrate restored TRESK current controlling neuronal hyperexcitability in a mouse model of oxaliplatin-induced peripheral neuropathic pain.

Chemotherapy-induced peripheral neuropathy (CIPN) and its related pain are common challenges for patients receiving oxaliplatin chemotherapy. Oxaliplatin accumulation in dorsal root ganglion (DRGs) is known to impair gene transcription by epigenetic dysregulation. We hypothesized that sodium butyrate, a pro-resolution short-chain fatty acid, inhibited histone acetylation in DRGs and abolished K channel dysregulation-induced neuronal hyperexcitability after oxaliplatin treatment.

Impact of the COVID-19 pandemic on clinical care and patient-focused outcomes of advanced nursing practice: A cross-sectional study.

Background: The COVID-19 pandemic has significantly impacted advanced practice nurses' practice and posed great challenges in patient care delivery.

Purpose: The aim of this study was to investigate the impact of the COVID-19 pandemic on the practice of advanced practice nurses in mainland China and Hong Kong Special Administrative Region (SAR). Methods A cross-sectional descriptive survey was conducted March 2021 and January 2022.

Training secondary school students as anti-smoke ambassadors using the service-learning model: A cluster randomized controlled trial with hybrid type 1 effectiveness-implementation design study protocol.

Background: Evidence shows that using the AWARD (Ask, Warn, Advise, Refer, Do-it-again) model with service-learning model in youngsters may be an appropriate strategy to refer young smokers for early smoking cessation services. Therefore this study aims to promote smoking cessation by training secondary school students as anti-smoke ambassadors (ASAs) with increased knowledge, skills and self-efficacy on smoking cessation and AWARD model using service-learning model.

Methods: A cluster randomized controlled trial will be conducted in 14 secondary schools in Hong Kong.