166 results match your criteria: "Ho Chi Minh City University of Education[Affiliation]"

For the first time, critical review on R. Br. (Boraginaceae) is established.

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is a human pathogen responsible for a variety of diseases, from skin, soft tissue, and lung infections to severe cases such as meningitis, infective endocarditis, and bacteremia. The high level of antibiotic resistance in these pathogens, exemplified by methicillin-resistant (MRSA), necessitates the development of effective antibiotics. Thus, this work introduced the chemical synthesis of ethyl 3,5-dibromoorsellinate, a derivative of ethyl orsellinate from the lichen mycobiont of , and its effectiveness against MRSA was assessed.

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Potential Antioxidant Compounds from the Spores of and the Branches of .

Antioxidants (Basel)

October 2024

Research Unit in Natural Products Chemistry and Bioactivities, Faculty of Science and Technology, Thammasat University Lampang Campus, Lampang 52190, Thailand.

Article Synopsis
  • The study investigated the antioxidant properties of bioactive extracts from spores and branches, measuring total phenolic content (TPC), total flavonoid content (TFC), and their ability to inhibit free radicals.
  • The highest antioxidant activities were found in the ethyl acetate extract of spores and the hexane-ethyl acetate extract of branches, both showing strong DPPH inhibition rates.
  • Additionally, the research identified several compounds, including a new natural compound, and highlighted one compound with particularly strong antioxidant activities, suggesting potential applications in natural product-based antioxidants.
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We theoretically demonstrated that helical-photon-dressed states determine the rotational directions of the π-electrons of aromatic ring molecules formed by a circularly polarized or an elliptically polarized laser. This theory was verified using a minimal three-electronic-state model under the frozen nuclei condition. The model consists of the ground state and either a doubly degenerate electronic excited state or two quasi-degenerate excited states.

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Background: Facebook* is one of the largest social media platforms in the world. The use of Facebook* can lead to several problems, such as Facebook* addiction. Previous studies have investigated the effects of reinforcing factors on problematic Facebook* use, but negative factors have been little studied.

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Adolescents experience numerous changes, both psychologically and physically, and they are also the age group with a high prevalence of mental problems that need counseling help. The study aims to assess the difficulties and the needs for psychological support, factors affecting the need to use psychological services among adolescents. A cross-sectional study was conducted on 672 high school students in Thu Duc City, Vietnam.

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Using a bio-guided isolation on the Vietnamese lichen based on alpha-glucosidase inhibition, eleven compounds were isolated and structurally elucidated, namely, protocetraric acid (1), 8'-methylstictic acid (2), stictic acid (3), 4,6-diformyl-8-hydroxy-3-methoxy-1,9-dimethyl-11-oxo-11-dibenzo[,][1,4]dioxepine-7-carboxylic acid (4), vicanicin (5), norstictic acid (6), diffractaic acid (7), barbatic acid (8), atranol (9), 5-chlorohaematommic acid (10), and eumitrin A1 (11). Their chemical structures were identified by extensive 1D and 2D NMR analysis and high-resolution mass spectroscopy and compared with those reported in literature. Protocetraric acid (1) and norstictic acid (6) were selected for further modification to derive new compounds, namely, 1a-1e and 6a.

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Chemical constituents with their alpha-glucosidase inhibitory activity from the whole plant of Ceratophyllum demersum.

Phytochemistry

January 2025

Research Unit in Natural Products Chemistry and Bioactivities, Faculty of Science and Technology, Thammasat University Lampang Campus, Lampang, 52190, Thailand. Electronic address:

From Ceratophyllum demersum growing in Vietnam, twelve compounds were isolated and structurally elucidated, including six previously undescribed compounds, demersones A-D (1-4), acetylvelutins A and B (8 and 9), together with six known compounds, (+)-cyclocolorenone (5), 1-hydroxycyclocolorenone (6), 10-hydroxycyclocolorenone (7), retusin (10), betulinic acid (11), and lupeol (12). The chemical structures and stereochemistry of 1-12 were identified through analysis of spectroscopic data (1D and 2D NMR and HRESIMS), ECD data, and DFT calculation. Notably, this is the first time that humulene-type (1 and 2), guaiane-type (3), and aromadendrane-type (4-7) sesquiterpenoids have been reported in this genus.

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Lichen is well-known for its various purposes. However, understanding the chemical composition and antimicrobial characteristics of cf. remains insufficient.

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and studies of alpha glucosidase inhibition and antifungal activity of husk.

RSC Adv

August 2024

Institute of Chemical Technology, Vietnam Academy of Science and Technology 1A TL29 Street, Thanh Loc ward, District 12 Ho Chi Minh City Vietnam

The coffea husk, a protected agricultural crop, is abundant in Vietnam. Examining the effects of husk compounds on α-glucosidase and antifungal drug activity was the primary objective of this research. A cholestane-type steroid, coffeacanol A (1), was extracted from the ethyl acetate extract.

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A theoretical perspective on grandiose narcissism suggests four forms of it (sanctity, admiration, heroism, rivalry) and states that these forms conduce to different ways of thinking and acting. Guided by this perspective, we examined in a multinational and multicultural study (61 countries; N = 15,039) how narcissism forms are linked to cognitions and behaviors prompted by the COVID-19 pandemic. As expected, differences in cognitions and behaviors across narcissism forms emerged.

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Mindfulness practices in schools have emerged as an educational effort that aims to promote the development of the competency and mental well-being of students. Specifically, mindfulness-based social-emotional learning (MBSEL) programs are an educational strategy that focuses on the improvement of social-emotional competence by cultivating awareness of the present moment through mindfulness activities. This study intended to investigate the benefits and limitations of the implementation of school-based mindfulness practice in a developing nation with a culturally diverse and multi-religious population.

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Article Synopsis
  • The study explores the impact of religiosity on mental health issues like depression and happiness among Vietnamese believers, highlighting a gap in existing research on this topic.
  • Conducted with 374 participants using PLS-SEM methodology, the findings reveal that intrinsic religiosity positively influences gratitude and the depression-happiness scale, with age moderating some of these effects.
  • Gratitude is identified as a key mediating factor, suggesting that it plays an essential role in understanding how religiosity affects mental well-being among religious individuals in Vietnam.
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Twelve compounds were isolated from aerial parts through phytochemical analysis and the genus is the first place where the compounds 4-6 and 11-12 have been found. Based on the ability to inhibit NO production in RAW264.7 cells, compound 2 has demonstrated the strongest anti-inflammatory activity with an IC of 7.

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Three new constituents from the stems of and their -glucosidase inhibitory activity.

Nat Prod Res

April 2024

Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.

Three new metabolites (-) were isolated from the stems of , along with five known compounds, including kaempferol (), quercetin (), isovanillic acid (), protocatechuic acid (), and gallic acid (). Their structures were deduced using NMR spectroscopic, mass spectrometric analyses, and literature data. The absolute configurations of - were established by electronic circular dichroism (ECD) spectroscopy.

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While metal-organic framework (MOF) photocatalysts have demonstrated a unique Cr(VI) photoreduction capability in recent decades, their performance is still insufficient for practical applications because of their low Cr(VI) uptake and poor visible light response. To cope with these drawbacks, a new OH-modified Zr-based MOF, termed HCMUE-1, was successfully prepared a solvothermal method in this work. The complete characterization of HCMUE-1 was performed through various techniques, including powder X-ray diffraction (PXRD), Raman spectroscopy, Fourier transform infrared (FT-IR), thermogravimetric analysis and differential scanning calorimetry (TGA-DSC), scanning electron microscopy combined with energy-dispersive X-ray (SEM-EDX), and X-ray photoelectron spectroscopy (XPS).

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Article Synopsis
  • - A bio-guided isolation process led to the discovery of six compounds from the Vietnamese lichen Roccella montagnei, including a new compound named montagneside A, alongside five known compounds.
  • - The chemical structures of these compounds were determined using advanced techniques like 1D and 2D NMR analysis and high-resolution mass spectroscopy.
  • - Evaluation of the compounds showed that D-erythrin and its derivatives significantly inhibited alpha-glucosidase activity, with the most active derivative being analyzed through molecular docking to understand its inhibitory mechanism.
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Article Synopsis
  • The text indicates a correction has been made to a previously published article.
  • The specific article can be identified by its DOI: 10.1039/D4RA00666F.
  • Corrections in academic articles are often made to clarify errors or provide updated information.
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A new cucurbitacin, 3-(-D-glucopyranosyloxy)-5,6:16,23-diepoxycucurbit-24-en-11-one or hygrocucurbin A , along with two known compounds, including 3-(-D-glucopyranosyloxy)-16,23-epoxycucurbita-5,24-dien-11-one and (+)-lyoniresinol , were isolated from the bark of . Their chemical structures were elucidated by spectroscopic NMR, HR-IDA- TOF-MS analysis, and by comparison with the spectral data of corresponding compounds in the literature. Two cucurbitacins and were evaluated for their -glucosidase inhibitory activity and cytotoxic against KB, MCF-7, Hep G2, and A549 cancer cell lines.

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Two new triterpenoid saponins, named spermacosides A-B (-), together with two known oleanane-type triterpenoid saponins, 3--D-xylopyranosyl-(1→3)-D-glucopyranosylbayogenin ( and 3---D-glucopyranosylbayogenin (), were isolated from the ethyl acetate extract of Burm.f. in a phytochemical investigation.

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Seven flavonoid glycosides were isolated from the aerial portions of during a phytochemical analysis. This comprised one novel component, ecurvoside, and six well-studied compounds, namely astragalin, isoquercitrin, nicotiflorin, rutin, hesperidin, and neohesperidin. The chemical structures of compounds were identified using spectroscopic techniques and a comparison with previously published studies.

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Foodborne zoonotic trematodiasis is a public health problem in many countries. A study on digenean larvae (cercariae stage) obtained from snails in all ten main small canals and two rice fields was carried out in Can Gio Mangrove Biosphere Reserve, Ho Chi Minh city, Vietnam to identify the snail composition and digenean prevalence in snails. The snails were sampled in the dry season (January 2022) and the wet season (June 2022).

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Two New Benzoquinone Derivatives from Vietnamese Knema globularia Stems.

Chem Biodivers

May 2024

Research Unit in Natural Products Chemistry and Bioactivities, Faculty of Science and Technology, Thammasat University Lampang Campus, Lampang, 52190, Thailand.

The chemical investigation of the stems of Knema globularia led to the isolation of two new benzoquinones derivatives, embenones A and B (1 and 2), along with three known compounds (3-5). The structures of the isolated compounds were determined using spectroscopic techniques, including HRESIMS, 1D and 2D NMR, in conjunction with comparison to existing literature data. Compounds 1 and 2 represent new carbon skeletons in nature.

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Globunoids A-D, undescribed bichalconoid and biflavanoids with α-glucosidase and α-amylase inhibitory activities from Knema globularia stems.

Phytochemistry

May 2024

Center of Excellence in Natural Products Chemistry, Department of Chemistry, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; Nanotec-CU Center of Excellence on Food and Agriculture, Department of Chemistry, Chulalongkorn University, Bangkok, 10330, Thailand. Electronic address:

A bichalconoid, globunoid A (1) and three biflavanones, globunoids B-D (2-4), previously undescribed, were isolated from the stems of Knema globularia, along with fourteen known analogues 5-18. The chemical structures of 1-4 were elucidated by the comprehensive spectroscopic analysis including UV, IR, HRESIMS, and NMR; the absolute configurations were determined based on their NOESY data, DP4+ statistical analysis, and ECD calculation. Up to now, compounds 2 and 3 represent the first 3,3″-linked biflavanone structures.

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Identification and -glucosidase inhibitory activity evaluation of two new coumarins derived from J. R. Drumm.

Nat Prod Res

February 2024

Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Pathumwan, Thailand.

Five coumarins were isolated from the heartwood of , which included two newly discovered compounds, namely 11-hydroxypopulene E () and mansorin D (), along with three previously identified compounds. The structures were determined through the utilisation of comprehensive spectroscopic data, ECD calculations, and a thorough comparison with existing literature data. The -glucosidase inhibitory activities of all isolated compounds were assessed in yeast.

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