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Context: The potential of lazaroid U-74389G in attenuating injury after ischemia and reperfusion has been reported in various organs.

Objective: The present study focuses specifically on the pancreas and aims to examine any effects of U-74389G in a swine model of pancreatic ischemia and reperfusion, encompassing ischemic preconditioning.

Methods: Twelve pigs, weighing 28-35 kg, were randomized into two experimental groups.

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