Metachronous Cutaneous Melanoma Metastases of the Left Anterior Paranasal Sinuses and the Right Nasopharynx That Were Treated Surgically: A Case Report With Literature Review.

Metastases of cutaneous melanoma to the paranasal sinuses and nasopharynx are considered rare. We reported the case of a patient with cutaneous melanoma metastasizing to the left anterior infundibulum and seven months later to the right nasopharynx that was successfully treated by endonasal endoscopic surgery as a single treatment modality. No adjuvant radiotherapy was performed.

Intracoronary Imaging: Current Practice and Future Perspectives.

Intracoronary imaging has brought new insight in the field of interventional cardiology. Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are the most commonly used imaging modalities. Regarding their technical characteristics IVUS and OCT have similarities as well as differences, a fact that could have significant clinical implications.

Acute Chest Syndrome in Sickle Cell Disease: Clinical Presentation and Outcomes. The Experience of a Single Thalassemia and Sickle Cell Unit in a University Hospital.

Acute chest syndrome (ACS) is a common cause of death for sickle cell disease patients. This syndrome is defined as: respiratory symptoms, new X-ray findings developed and/or fever; ACS requires prompt treatment to avoid clinical deterioration and death in adults with sickle cell disease. Sixteen episodes of acute chest syndrome were studied in 16 adults with sickle cell disease.

Can the upper esophageal sphincter contractile integral help classify achalasia?

Background: The use of high-resolution manometry (HRM) in achalasia patients has revealed abnormal findings concerning upper esophageal sphincter (UES) function. The introduction of the UES contractile integral (UES-CI), as with the distal contractile integral (DCI), may complement the interpretation of the manometric study of achalasia subtypes, defined by the Chicago Classification v3.0.

CT in appendicitis.

Appendicitis is the most common abdominal emergency occurring in 7%-12% of the population. The aim of this article was to pictorially present the spectrum of appendix and acute appendicitis appearances on computed tomography (CT). The various appearances on CT of the normal appendix are shown as well as the CT criteria for the differentiation of perforated and non-perforated appendicitis.

Hashimoto encephalopathy with pegylated interferon alfa-2b and ribavirin.

Objective: To report an instance of Hashimoto encephalopathy probably resulting from pegylated interferon alfa-2b and ribavirin.

Case Summary: A 36-year-old woman with a 10-year history of autoimmune thyroiditis presented with symptoms and signs consistent with Hashimoto encephalopathy during therapy with pegylated interferon alfa-2b and ribavirin for chronic hepatitis C.

Discussion: Hashimoto encephalopathy is a rare autoimmune condition that occurs in patients with Hashimoto thyroiditis and high titers of antithyroid antibodies.