Guillain-Barre syndrome following Pfizer-BioNTech (BNT162b2) vaccination: a case report.

Introduction: Pfizer-BioNTech (BNT162b2) is one of the mRNA vaccines currently approved by the WHO and the Food and Drug Administration (FDA) against COVID-19.

Case Presentation: Here, the authors report a case of an 8-year-old female with Guillain-Barré syndrome following the second dose of Pfizer-BioNTech (BNT162b2) vaccination requiring respiratory support who was managed with intravenous immunoglobulin.

Discussion: There have been reports of Guillain-Barré syndrome following the Pfizer-BioNTech vaccination.

Silicone blockers for bronchial leaks: Expanding the literature base with a larger and longer experience in this complex entity.

Innovative techniques using silicone blockers for bronchial leaks where options are few, stakes are high and favourable outcomes can be achieved in a short span of time.

Job Satisfaction among Medical Doctors in Nepal: A Descriptive Cross-sectional Study.

Introduction: Job satisfaction is an attitudinal variable representing the extent to which people like or dislike their jobs. It is a critical factor influencing healthcare quality, patient outcomes, and overall well-being in medical professionals. This study aimed to determine Job Satisfaction among medical doctors in Nepal.

Sepsis among Patients Admitted to the Intensive Care Unit of a Tertiary Care Centre.

Introduction: Sepsis is a life-threatening dysfunction and is one of the common causes of admission in intensive care units. Early diagnosis and management improves the outcome of patients. The aim of this study was to find out the prevalence of sepsis among patients admitted to the intensive care unit of a tertiary care centre.

Cervical Ectopic Pregnancy with Unsupervised Intake of Medications for Abortion: A Case Report.

Unlabelled: Cervical ectopic pregnancy is the rarest form of ectopic pregnancy, where implantation occurs in the mucosa of the endocervical canal, below the internal os. Medical abortion is a safe and effective method of termination of early intrauterine pregnancies when carried out under the supervision of trained service providers. Unfortunately, unsupervised misuse of such methods can lead to grave morbidities, especially in ectopic pregnancies.

Community-acquired Pneumonia among Elderly Patients Admitted to the Department of Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

Introduction: Community-acquired pneumonia is an acute infection of lung tissue in an immunocompetent patient who have not recently been hospitalized or has been hospitalized for less than 48 hours and acquired it in the community. It continues to have a substantial effect on the elderly, who are impacted more often and severely than younger groups. It is the third most common hospital diagnosis in adults over the age of 65 years, and the sixth major cause of mortality in developed nations.

Left circumflex STEMI presenting as de Winter sign, an ECG Zebra that gives you the chills! A case report.

de Winter ECG sign is an anterior ST-segment elevation myocardial infarction equivalent, which refers to an occlusion of the proximal left anterior descending (LAD) coronary artery with tall T waves and the absence of ST elevations in the precordial leads on the electrocardiogram (ECG). This sign is often under-recognized and not treated as an ST-segment elevation myocardial infarction which can increase the morbidity and mortality of such a life-threatening condition. Here we report a characteristic de Winter ECG sign involving left circumflex artery as culprit vessel, which was managed with PCI.

Dengue Fever in a Neonate: A Case Report.

Unlabelled: Dengue is one of the most common viral infections affecting the general population in endemic areas annually. However, it is barely reported in newborns owing to a widespread belief that they are protected from severe viral infections in the first six months of life by the presence of maternal antibodies. Here we present a case of a 23-day-old male infant born to primigravida with dengue fever with the post-natal transmission of infection.

Poisoning among Patients Presenting to the Department of Emergency Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study.

Introduction: Poisoning is one of the major public health problems worldwide. The World Health Organization has estimated 0.3 million deaths a year due to various poisoning agents; pesticides being the leading one.

COVID-19 and Sepsis in an Atypical Case of Mixed Connective Tissue Disorder Presenting With a Myasthenic Crisis.

Myasthenia gravis (MG) is an autoimmune illness that causes neuromuscular junctions to be damaged by anti-acetylcholine receptor antibodies. It is a very rare condition that is more common among women. Fatigable fluctuating diplopia or ptosis is the characteristic early appearance of this condition.

An Exceptionally Rare Primary Epithelioid Rhabdomyosarcomas of the Stomach: A Case Report.

Rhabdomyosarcoma (RMS) is a common soft tissue tumor in adults, but RMS's causes and risk factors are unknown. We present a case of a 62-year-old man with RMS who presented with feelings of fullness after meals and vomiting for the previous five months with anorexia and weight loss for four months. He reported feeling a rolling mass in his belly that moves from left to right.

Medulloblastoma in an Adult Female Patient: A Rare Presentation.

Medulloblastoma (MB) is an aggressive malignant tumor of the posterior fossa of the CNS that mainly affects children younger than 15 years of age. It is uncommon in the adult population compared to children. Any adult patient presenting with cerebellar mass must be evaluated with brain tissue biopsy to rule out MB.

COVID-19 Reinfection in a Young Medical Doctor: A Case Report.

There is hardly any report of reinfection due to coronavirus disease 2019 (COVID-19) in medical professionals from Nepal. We report a case of a 32-year-old doctor with COVID-19 reinfection. Symptoms during the first infection were mild.

Prevalence of Type II Diabetes Mellitus Among Adult Population in Medical Department of A Tertiary Care Centre.

Introduction: Diabetes mellitus is a chronic metabolic disease that is mainly associated with a number of lifestyle behaviors. There is a high discrepancy among urban and rural populations with the prevalence of diabetes in rural areas as 2.5% and a high prevalence of 14.

Incidental diagnosis of paragonimiasis after histopathological examination of cholecystectomy specimen in Nepal: A case report.

Introduction: Paragonimiasis or lung fluke disease is a typical food-borne parasitic zoonosis caused by infection with . The is a trematode that mainly infects the lungs of humans after eating an infected raw or undercooked crab or crayfish.

Case Presentation: Herein we report a case of peritoneal Paragonimiasis in the gallbladder of a 58-year-old female from Rukum district of Nepal.

Characteristics of Isolated From Clinical Specimens in a Tertiary Care Hospital, Kathmandu, Nepal.

Introduction: Methicillin resistant (MRSA) is a major human pathogen associated with nosocomial and community infections. A gene is considered one of the important virulence factors of responsible for acquiring resistance against methicillin. The main objective of this study was to explore the prevalence, antibiotic susceptibility pattern, and A gene.

Prevalence of Hypertension in Adult Population of A Village of Nepal.

Introduction: Hypertension is a cardiovascular disorder rapidly emerging as a major health problem in developing countries. Uncontrolled or poorly managed hypertension leads to several complications such as coronary heart disease, peripheral vascular disease and kidney disease. These complications account for approx 9.