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Content-Based Dermatological Lesion Retrieval (CBDLR) systems retrieve similar skin lesion images, with a pathology-confirmed diagnosis, for a given query image of a skin lesion. By producing an intuitive support to both inexperienced and experienced dermatologists, the early diagnosis through CBDLR screening can significantly enhance the patients' survival, while reducing the treatment cost. To deal with this issue, a CBDLR system is proposed in this study.

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