318 results match your criteria: "Higher Institute of Health[Affiliation]"

Background: Unsafe abortions represent a significant public health issue in Cameroon, often resulting in severe health consequences. This study aimed to investigate the prevalence, motivations, and factors associated with unsafe abortions among women in Yaoundé, Cameroon.

Methods: A cross-sectional study was conducted among women of childbearing age attending three urban health facilities in Yaoundé, Cameroon.

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The present study aimed to evaluate the antimicrobial activity of aqueous extracts of the mixture of spices used as accompanying soup of braised fish against multidrug resistant (MDR) bacteria isolated from raw and braised fish collected in the city of Bangangté, Cameroon. A survey was conducted in the city of Bangangté to diagnose the braising fish processes. Pathogens were isolated from raw and braised fish samples collected in fish farms and selling points, and their susceptibility to 16 commonly used antibiotics was tested using the Kirby-Bauer disk diffusion method.

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Objectives: The objectives of this review and meta-analysis were twofold: first, to determine the prevalence of substance use among school-going children in Arab and African countries; and second, to highlight the considerable influence of variables such as the nation's region and the timeframe of the study on the prevalence of substance use.

Methods: Research was sourced from Science Direct, Scopus, Web of Science, Google Scholar, and PubMed. Thirty-seven articles were incorporated in accordance with the PRISMA guidelines.

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Objectives: Individuals after traumatic brain injury (TBI) commonly experience a variety of symptoms that impact their daily life functioning. This study aims to evaluate the applicability, validity, and reliability of the health-related Quality of Life after Brain Injury (QOLIBRI) questionnaire in the Moroccan context.

Methods: This multicentric cross-sectional study included 203 individuals after TBI in medical centers from three different cities at a mean of 4.

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Background: Nonprimary osteochondral lesions of the talus (OLT) pose a significant challenge in orthopaedics, with no definitive consensus on optimal surgical treatment.

Purpose: To consolidate the most recent evidence on operative treatments for nonprimary OLT by assessing patient-reported outcomes (PROs), postoperative complications, and clinical failures.

Study Design: Systematic review; Level of evidence, 4.

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Investigation of organs dosimetry precision using ATOM phantom and optically stimulated luminescence detectors in computed tomography.

Biomed Phys Eng Express

December 2024

Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan 1st University, Settat, Morocco.

Article Synopsis
  • * Significant discrepancies were found between the measured and estimated doses across various organs, with p-values consistently below 0.05, indicating the differences are statistically significant.
  • * The findings suggest that OSLD measurements can provide a more accurate assessment of organ doses in CT imaging and highlight the need for improved dose estimation models to enhance patient care.
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 In Morocco, cancer is a disease with a concerning incidence to the point that patients are diagnosed at advanced stages. As a result, patient care requires a holistic approach, integrating medical treatment and appropriate psychosocial support to improve their well-being. This study aimed to evaluate the psychosocial care competencies of oncology healthcare professionals at the Mohammed VI University Hospital Center (CHU) in Marrakech.

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In radiation dosimetry, achieving electronic equilibrium is vital for accurate dose measurements in radioprotection. This study investigates the effect of Poly Methyl Methacrylate (PMMA) layers, known by its chemical formula CHO and a density of 1.19 g/cm³ (PNNL, 2011), on electronic equilibrium for the calibration of radiation protection instruments, focusing on photon beams of varying energies.

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Objectives: To provide a comprehensive review of the use of electronic patient-reported outcomes measures (ePROs) as digital health tools to assess health-related quality of life (HRQoL) in women with breast, ovarian, cervical, and endometrial cancers.

Methods: A systematic review was conducted to identify studies that used ePROs to evaluate HRQoL in women diagnosed with breast and gynecological cancers. The review followed the 2020 update of the PRISMA guidelines and a pre-registered protocol in PROSPERO (CRD42024516737).

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Purpose: This paper aims to contribute to the existing literature in the field of hospital governance by exploring the relationship between the attributes and performance of hospital boards and hospital performance in terms of quality of healthcare.

Design/methodology/approach: A survey of board performance in public hospitals in Morocco was carried out, in which we surveyed all board members of the 13 hospitals in the Casablanca-Settat region. A total of 82 members responded (82% response rate) to the previously adapted and validated self-evaluation questionnaire on board self-assessment questionnaire (BSAQ) board member performance.

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Introduction: Breast cancer is a major public health concern worldwide and the most prevalent form of cancer in Morocco. This study aimed to describe the histological and immunohistochemical profiles of breast cancer in women admitted to Cheikh Khalifa Hospital in Casablanca, Morocco.

Methods: This is a retrospective cross-sectional study.

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Article Synopsis
  • The study investigates a new water-soluble polysaccharide called PSP extracted from leaves, using techniques like FT-IR and NMR to identify its chemical structure.
  • HPLC analysis shows that PSP is a heteropolysaccharide made up of two types of monosaccharides, with additional assessments revealing its semi-crystalline nature and various functional properties.
  • The research highlights PSP's antioxidant potential in food preservation, particularly in ground beef, where it significantly inhibits lipid oxidation, microbial growth, and demonstrates stability in color, pH, and moisture.
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Introduction: the increasing demands and responsibilities placed upon teachers are causing overwhelming stress. As a result, many teachers struggle with managing their workload effectively, which increases their susceptibility to burnout. This study aims to investigate burnout among high school teachers in Tetouan, Morocco, and explore the various contributing factors.

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Human PapillomaVirus Vaccine Uptake: Attitudes and Practices Among Moroccan Physicians.

J Cancer Educ

December 2024

Laboratory of Research in Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, BP 555, Settat, Morocco.

Article Synopsis
  • Cervical cancer represents a significant public health issue in Morocco, with 2,165 new cases and 1,199 deaths reported in 2020; despite the availability of the HPV vaccine since 2008, awareness among physicians is low.
  • A study involving 500 physicians revealed that only 36.6% were aware of the main HPV types linked to cervical cancer, and only 16.6% actively recommended the HPV vaccine, although over 63% expressed willingness to recommend it if aware.
  • Key factors influencing vaccine recommendation included physicians' age, work sector (with public sector doctors more likely to recommend it), and awareness of HPV types, vaccine schedules, and its commercial name, underlining gaps that need addressing
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Residual transmission of HIV infection from mother to child in the Atlantic and littoral departments in Benin.

BMC Pediatr

October 2024

Laboratory of Biology and Molecular Typing in Microbiology (LBTMM), Faculty of Sciences and Technology (FAST), University of Abomey - Calavi, Cotonou, 05 BP 1604, Benin.

Article Synopsis
  • The study evaluates the effectiveness of WHO's recommendations in Benin regarding the prevention of HIV transmission to exposed infants, using data from 2016 to 2021.* -
  • Analysis involved 5,312 infants, revealing a 3.4% overall HIV transmission rate, impacted by factors such as maternal treatment methods and feeding practices, with lower transmission linked to mothers on tritherapy.* -
  • The findings highlight the success of the PMTCT program in reducing HIV transmission among infants, emphasizing the importance of consistent treatment for mothers of childbearing age.*
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Background: Malaria is a global disease burden, especially in Africa, with Nigeria having the highest prevalence of malaria, with approximately 50% affecting children. Children under five years of age are vulnerable to the risk of malaria spread. This research aimed to identify the determinants of malaria spread among children under the age of 5 in Nigeria.

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Opportunistic Infections in HIV-Infected Children on Treatment in Southern Morocco: A 12-Years Retrospective Follow-up Study.

Infect Chemother

September 2024

Laboratory of Mother-Child Health and Nutrition Research, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University of Rabat, Rabat, Morocco.

Background: Human immunodeficiency virus (HIV) infection in children is a significant public health concern, increasing the risk of infant mortality. Immunodeficiency caused by HIV favors the development of opportunistic infections (OIs), which are responsible for over 90% of HIV-related deaths. This study seeks to determine the primary OIs in children with HIV followed at the Hassan II Regional Hospital Center in Sous Massa, during the period from 2012 to 2023.

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Mechanism of Alzheimer type II astrocyte development in hepatic encephalopathy.

Neurochem Int

November 2024

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Miami School of Medicine, Miami, FL, USA; General Medical Research, R&D Services, Department of Veterans Affairs, Miami, FL, USA; Neuropathology Section, Veterans Affairs Medical Center, Miami, FL, USA; R&D Services and South Florida VA Foundation for Research and Education Inc, Veterans Affairs Medical Center, Miami, FL, USA. Electronic address:

Article Synopsis
  • Type C hepatic encephalopathy (Type C HE) is a neurological disorder resulting from chronic liver failure, presenting symptoms like mental confusion and motor difficulties.
  • The increase in Alzheimer type II astrocytes (AT2A) is a significant finding linked to Type C HE, though the development of AT2A and its role in cognitive impairments is still unclear.
  • Research in rats indicates that elevated oxidative stress, inflammation, and specific signaling pathways contribute to the rise of GMF and AT2A, leading to cognitive and motor deficits, suggesting potential targets for treatment.
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Article Synopsis
  • * Out of 1330 individuals, 1200 consented to participate; the study found a T2DM prevalence of 10.74%, and identified significant risk factors including age, family history of diabetes, obesity, and hypertension.
  • * The findings highlight the need for a national program in Burkina Faso to control diabetes and promote early detection to manage and prevent complications effectively.
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Background Informed consent is an essential component of medical practice, particularly in surgical procedures, as it guarantees that patients are thoroughly informed of the risks, benefits, and alternatives prior to receiving treatment. Nevertheless, research has demonstrated that patients frequently fail to recall critical information that was conveyed during the informed consent process, which emphasizes the potential for communication and comprehension deficiencies. Objective The objective of this study was to evaluate the quality of informed consent and the decision-making preferences of patients who are undergoing surgical procedures.

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In recent times, exploring the protective potential of medicinal plants has attracted increasing attention. To fight reactive oxygen species (ROS), which are key players in hepatic, cerebral and renal diseases, scientists have directed their efforts towards identifying novel compounds with antioxidant effects. Due to its unique composition, significant attention has been given to Cactus Seed Oil (CSO).

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In the context of designing innovative anticancer agents, the synthesis of a series of chalcones bearing a 3,4,5-trimethoxylated A ring and a variety of B rings, including phenols and original heterocycles such as chromones, was conducted. For this end, Claisen-Schmidt condensation was performed in basic or acidic conditions between the common starting material 3,4,5-trimethoxyacetophenone and appropriate aldehydes; this allowed the recovery of fifteen chalcones in moderate-good yields. The synthesized compounds were screened for their antiproliferative activity against colorectal and prostatic cancer cells, using a colorimetric MTT assay.

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Unlabelled: The quality of life of breast cancer patients is strongly affected by physical pain, psychological distress, and uncertainty about vital prognosis.

Objective: To assess breast cancer patients' mental well-being and level of psychological distress at the Mohammed VI University Hospital in Marrakech.

Methods: Cross-sectional study carried out from April to December 2023 at the Mohammed VI University Hospital of Marrakech.

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Digital health for cancer symptom management in palliative medicine: systematic review.

BMJ Support Palliat Care

November 2024

Hassan First University of Settat, Higher Institute of Health Sciences, Laboratory of Health Sciences and Technologies, Settat, Morocco.

Background: Digital health technologies (DHTs) play a crucial role in symptom management, particularly in palliative care, by providing patients with accessible tools to monitor and manage their symptoms effectively. The aim of this systematic review was to examine and synthesise the scientific literature on DHTs for symptom management in palliative oncology care.

Methods: A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for systematic reviews and meta-analyses from 2 June to 20 June 2024.

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Article Synopsis
  • * The research analyzed data from 15 CDQ assessments across 12 countries over 16 years, discovering that comprehensive PPs correlate positively with better HRQoL, while policies focused solely on gluten-free meals aren't as effective on their own.
  • * The study emphasizes the need for enhanced patient education and effective regulation monitoring to support CD patients and improve their overall well-being.
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