Occurrence of pre- and postharvest multi-mycotoxins in durum wheat grains collected in 2020 and 2021 in two climatic regions of Tunisia.

Twenty two mycotoxins in 136 durum wheat collected from Tunisia in 2020 and 2021 were investigated. Mycotoxins were analyzed by UHPLCMS/MS. In 2020, 60.

Prevention and Detoxification of Mycotoxins in Human Food and Animal Feed using Bio-resources from South Mediterranean Countries: a Critical Review.

Mycotoxins, which are natural toxic compounds produced by filamentous fungi, are considered major contaminants in the food and feed chain due to their stability during processing. Their impacts in food and feedstuff pollution were accentuated due the climate change in the region. They are characterized by their toxicological effects on human and animal health but also by their harmful economic impact.

Anti-Obesity Actions of Two Separated Aqueous Extracts From Arbutus () and Hawthorn () Fruits Against High-Fat Diet in Rats via Potent Antioxidant Target.

and are widely distributed throughout the Mediterranean basin and commonly used in folk medicine against a wide range of diseases. Therefore, the present study has been designed to evaluate the anti-obesity potential of two aqueous extracts of the fruits of (AUAE) and (CMAE). Male rats were supplied with a standard diet (SD), high-fat diet (HFD), HFD with the two separated extracts at the same dose (300 mg/kg, BW, p.

Protective Effect of Tunisian Red Seaweed () Against Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress in Rats.

Idiopathic pulmonary fibrosis is a chronic and progressive respiratory disease whose diagnosis and physiopathogenesis are still poorly understood and for which, until recently, there were no effective treatments. Over the past few decades, many studies have demonstrated that marine macroalgae such as red seaweeds are potential alternative sources of useful bioactive compounds possessing various physiological and biological activities. The present study was aimed to investigate the effect of aqueous extract (COAE) against bleomycin (BLM)-induced lung fibrosis in rat.

Hepato-Nephroprotective Actions of Decoction Extract Against Extraintestinal Alterations Induced with Acetic Acid-Colitis Model in Rats.

Inflammatory bowel disease is associated with multiple extraintestinal disorders, including hepato-nephrological disruptions. The aim of this study was to evaluate the hepato-nephroprotective effect of leaf decoction extract (SLDE) on acetic acid (AA)-induced colitis accompanied with liver and kidney injuries. albinos rats were pretreated with SLDE (50, 100, and 200 mg kg, b.

LC-ESI-MS phenolic contents assessment, antioxidant, and protective ability of root bark extract against ethanol-induced gastric ulcer in rats: H, K-ATPase inhibitory pathway study.

The objectives of the current study were to evaluate the root bark extract's (PGE) antioxidant and gastroprotective activities against ethanol-induced gastric ulcers in Wistar rats and to elucidate the putative mechanism of action using analysis. The PGE phytochemical study shows high levels of phenolics, flavonoids, tannins, and polysaccharides. , the PGE was more effective at scavenging hydroxyl radicals than quercetin and had lower ferric reducing activity than catechin.

HPLC analysis, mycochemical contents and biological activities of two edible hypogeous ascomycetes: and .

Truffle, the hypogeous, ascomycetous macrofungus, has been recognized as a delicacy for centuries, and it is gaining elevated status in the culinary domain. The chemical composition and biological activities of aqueous extract and ground material of two desert Tunisian and were studied for the first time. Using three assays antioxidant activity of the aqueous extract and ground material of the two truffles were investigated.

Enhanced textile dye removal from wastewater using natural biosorbent and Shewanella algae B29: Application of Box Behnken design and genomic approach.

In this study, Box-Behnken design combining seven factors at three levels were used to optimize the elimination of CI Reactive Red 66 in artificial seawater, by the combination of eco-friendly bio-sorbents and acclimated halotolerant microbial strain. Results showed that macro-algae and cuttlebone (2 %) were the best natural bio-sorbent. Additionally, the selected halotolerant strain able to rapidly remove dye was identified as Shewanella algae B29.

Nematicidal Effect of Raphasatin from Against .

The nematicidal activity of radish bulb () methanol (RME) and aqueous extracts (RAE) was tested against the second stage (J) root knot nematode model. The EC of RME after 3 d of J immersion in test solutions was 312 ± 65 μg/ml. However, no activity was noted for RAE (EC > 1,000 μg/ml).

Development of active edible coatings based on fish gelatin enriched with extract: Application in fish () fillet preservation.

An edible coating was developed using gelatin extracted from the skin of gray triggerfish () and applied to the fillet of the smooth-hound shark (). leaf extract was added to gelatin coating solution to improve its preservative properties. The phenolic profiles and antioxidant and antibacterial activities of extracts were determined.

Inhibitor Assessment against the LpxC Enzyme of Antibiotic-resistant Acinetobacter baumannii Using Virtual Screening, Dynamics Simulation, and in vitro Assays.

Background: Bacterial resistance is currently a significant global public health problem. Acinetobacter baumannii has been ranked in the list of the World Health Organization as the most critical and priority pathogen for which new antibiotics are urgently needed. In this context, computational methods play a central role in the modern drug discovery process.

Dose-dependent Action of on Colonic Dysmotility and Ex Vivo Spontaneous Intestinal Contraction Modulation.

Ginger () rhizomes are commonly used in foods and employed for many ailments including gastrointestinal disorders. Our main objective was to evaluate the effect of aqueous extract (ZOAE) on gastrointestinal (GI) physiological motility and colonic dysmotility. Thereby, rats were given loperamide (LP, 3 mg/kg, b.

Plant growth promoting rhizobacteria modulates the antioxidant defense and the expression of stress-responsive genes providing Pb accumulation and tolerance of grass pea.

To ensure the success of phytoremediation, it is important to consider the appropriate combination of plants and microorganisms. This study was conducted to get a better insight into the underlying molecular and biochemical mechanism of grass pea (Lathyrus sativus L.) induced by plant growth promoting rhizobacteria (PGPR), when exposed for 3, 6, 9, and 14 days to 1 mM Pb in a hydroponic system.

Tunisian Horehound () Aqueous Extract Improves Treatment of Bleomycin-Induced Lung Fibrosis in Rat.

Pulmonary fibrosis (PF) remains one of the most serious pneumopathies whose diagnosis and physiopathogenesis are still poorly understood and no treatment has been shown to be effective. Recently, many studies have shown a renewed interest in plants thanks to their pharmacological potentials, like horehound, known, for its anti-inflammatory and antioxidant activities. The present study investigated the effects of the aqueous extract of horehound (Mae) on bleomycin (BLM)-induced PF in rats.

Protective Effect of Extracts Against Bleomycin-Induced Pulmonary Fibrosis in Rats.

Pulmonary fibrosis (PF) is a fibrous interstitial pneumonia that causes damage to the lung tissue and thus alters all respiratory functions. In this study, we aim to investigate the therapeutic effects of fresh leaves of extracts on bleomycin (BLM)-induced (PF). Twenty-four rats were divided into four groups.

Acaricidal and anthelmintic efficacy of Ocimum basilicum essential oil and its major constituents estragole and linalool, with insights on acetylcholinesterase inhibition.

The present study evaluated the acaricidal and anthelmintic action of Ocimum basilicum essential oil and its main components against ticks and helminth parasites as well as to relate these activities to acetylcholinesterase inhibition. The in vitro acaricidal activity against Hyalomma scupense was evaluated by Adult Immersion Test (AIT) and Larval Packet Test (LPT), while the in vivo nematocidal potential was assessed in laboratory mice infected with Heligmosomoides polygyrus using fecal egg count reduction (FECR) and total worm count reduction (TWCR). Chemical analyzes were performed by gas chromatography coupled to mass spectrometry (GC-MS).

Seasonal patterns of microplastics in surface sediments of a Mediterranean lagoon heavily impacted by human activities (Bizerte lagoon, Northern Tunisia).

In this paper, we investigated seasonal variations in concentrations of microplastics (MPs) in surface sediments of a lagoon heavily impacted by human activities, located in northern Tunisia (the Bizerte lagoon, southern Mediterranean Sea). Analyses of 112 sediment samples collected from 28 stations between May 2019 and February 2020 revealed significant seasonal variation in concentrations of total MPs, with the highest levels recorded in August 2019 (109.6 ± 59.

The ameliorative effect of BEJ01 against FB1 induced spermatogenesis disturbance, testicular oxidative stress and histopathological damage.

Fumonisin B1 (FB1) is a possible carcinogenic molecule for humans as classified by the International Agency for Research on Cancer (IARC) in 2B group. In livestock, it is responsible for several mycotoxicoses and economic losses. strains, inhabitants of a wide range of foodstuffs and the gastrointestinal tract, are generally recognized as safe (GRAS).

Gastroprotective and Antioxidant Properties of Seeds Aqueous Extract (Fenugreek) and Omeprazole Against Ethanol-Induced Peptic Ulcer.

(Fenugreek) is used in traditional phytomedicine for its anti-inflammatory, antiseptic, antidiabetic, and several other therapeutic virtues. The current study was intended to investigate the protecting effects of fenugreek seeds' aqueous extract (FSAE) using experimentally ethanol (EtOH)-induced gastric peptic ulcer in rats, as immense alcohol consumption can lead to gastric ulcer. Sixty adult male Wistar rats were divided into 6 groups of 10 each: control, EtOH (4 g/kg body weight [b.

Effects of Growth Medium Variation on the Nutri-Functional Properties of Microalgae Used for the Enrichment of Ricotta.

Research Background: Microalgae represent an emergent sustainable source of bioactive compounds such as antioxidants, vitamins, minerals and polyunsaturated fatty acids that can ameliorate the nutritional characteristics of foods. The biochemical composition of microalgae could be modulated by varying the culture conditions to enhance the accumulation of biomolecules of interest. The aim of this work is to optimise the nutri-functional properties of two microalgae that can be used in food production.

Efficacy of synergistic activity of seed oils from (Safflower) and (Watercress) on the lethality of the cattle tick (Acari: Ixodidae).

Background: Ticks and tick-borne diseases are a severe economic and public-health problem for cattle producers. The emergence of acaricide resistance to synthetic chemical treatments has prompted interest in developing alternative tick control methods.

Aim: The main objective of the current research was to identify the chemical structure of and seed oils and to assess their anti-tick properties against ticks both alone and in combination (1:1).

Antioxidant Properties of Decoction Extract and Mechanism of Its Protective Effects on Ethanol-Induced Liver and Kidney Injuries.

This study assessed the hepato- and nephroprotective effects of flowers decoction extract (SODE) against ethanol (EtOH)-induced oxidative stress in rats as well as the possible mechanism implicated in such protection. Animals were divided into four groups: control, EtOH, and EtOH+SODE. Wistar rats were pretreated with SODE (50, 100, and 200 mg/kg, body weight [b.

Squeezed vacuum interaction with an optomechanical cavity containing a quantum well.

We investigate a hybrid system consisting of an optomechanical resonator and an optical cavity containing a quantum well. The system is coupled to a squeezed vacuum reservoir. We analyze the effect of the injection of squeezed photons inside the cavity on the intensity spectrum.