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Objective: To investigate the immune response and the protection in mice induced by the recombinant myophilin protein of Echinococcus granulosus.

Methods: Thirty-six male ICR mice of 6-8 weeks old were randomly divided into groups A, B and C each with 12. The mice in the 3 groups were subcutaneously immunized with Eg myophilin protein, blank plasmid protein or PBS, respectively, by 3 times and challenged with protoscoleces of E.

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