2 results match your criteria: "High Institute of Biotechnology of Sidi Thabet (ISBST)[Affiliation]"
Astaxanthin inhibits aldose reductase activity in , a model of type 2 diabetes and diabetic retinopathy.
Food Sci Nutr
December 2019
Laboratory of Physiopathology, Food and Biomolecules (PAB): LR17ES03 The High Institute of Biotechnology of Sidi Thabet (ISBST) University of Manouba (UMA) Sidi Thabet Tunisia.
Astaxanthin (ATX) is a marine carotenoid known for its powerful antioxidant and neuroprotective properties. In this study, we investigated the in vitro and in vivo potential inhibitory effect of ATX on the aldose reductase (AR) activity, a key enzyme in the polyol pathway responsible for the pathogenesis of diabetic complications including diabetic retinopathy (DR). The gerbil (), an animal model for type 2 diabetes and DR has been used.
View Article and Find Full Text PDFStudy of retinal neurodegeneration and maculopathy in diabetic Meriones shawi: A particular animal model with human-like macula.
J Comp Neurol
September 2017
Laboratory of Physiopathology, Food and Biomolecules (PAB), department of Biotechnology, High Institute of Biotechnology of Sidi Thabet (ISBST), Univ Manouba (UMA), BiotechPole Sidi Thabet, Sidi Thabet, Tunisia.
The purpose of this work was to evaluate a potentially useful animal model, Meriones shawi (M.sh)-developing metabolic X syndrome, diabetes and possessing a visual streak similar to human macula-in the study of diabetic retinopathy and diabetic macular edema (DME). Type 2 diabetes (T2D) was induced by high fat diet administration in M.
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