Utilization of Magnesium for the Treatment of Chronic Pain.

Context: The International Association for the Study of Pain (IASP) defines chronic pain as pain that persists or recurs for longer than 3 months. Chronic pain has a significant global disease burden with profound effects on health, quality of life, and socioeconomic costs.

Evidence Acquisition: Narrative review.

Alterations in GLUT1 and GLUT3 glucose transporter gene expression following unilateral hypoxia-ischemia in the immature rat brain.

The brain damage produced by unilateral cerebral hypoxia-ischemia in the immature rat results from major alterations in cerebral energy metabolism and glucose utilization which begin during the course of the insult and proceed into the recovery period. Consistent with a lack of pathology, the alterations in the hemisphere contralateral to the carotid artery ligation are transient and return to normal within 24 h of recovery, whereas the hemisphere ipsilateral to the ligation exhibits both early and late responses, and infarction. The facilitative glucose transporter proteins mediate glucose transport across the blood-brain barrier (55 kDa GLUT1), and into neurons and glia (GLUT3 and 45 kDa GLUT1), and demonstrate both early and late responses to perinatal hypoxia-ischemia.

Intraperitoneal distribution imaging prior to chromic phosphate (P-32) therapy in ovarian cancer patients.

This study addressed the technique of intraperitoneal distribution imaging (IDI). A literature search (MEDLINE database) revealed wide variations in IDI techniques without a basis for comparison. From April 1990 to September 1992, the authors studied 8 patients (age 43-65 years) with ovarian cancer.

Scintigraphy of torsion in triorchidism.

A 24-yr-old male who experienced fleeting episodes of left scrotal pain since the age of 13 had an ultrasound that suggested testicular duplication on the side (triorchidism). Five months later he had acute left scrotal pain lasting for 12 hr. At that time routine scrotal scintigraphy revealed late torsion and an additional sitting view demonstrated triorchidism.