763 results match your criteria: "Henry M Goldman School of Dental Medicine[Affiliation]"

A dentigerous cyst (DC) is the most common developmental cystic lesion of the jaws. Histologically, these cysts derive from the odontogenic epithelium that includes the reduced enamel epithelium, epithelial cell rests of Serres, and epithelial cell rests of Malassez. Radiographically, DCs are usually presented as well-defined radiolucencies associated with the crown of an unerupted tooth at the level of the cementoenamel junction (CEJ).

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Objective: This narrative review aims to explore the current applications and future prospects of AI within the subfields of oral and maxillofacial surgery (OMS), emphasizing its potential benefits and anticipated challenges.

Methods: A detailed review of the literature was conducted to evaluate the role of AI in oral and maxillofacial surgery. All domains within OMS were reviewed with a focus on diagnostic, therapeutic and prognostic interventions.

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The efficacy of facial skeletal treatment options in the management of obstructive sleep apnea.

J Prosthodont

January 2025

Department of Orthodontics & Dentofacial Orthopedics, Santa Barbara Facial Reconstruction, Santa Barbara, California, USA.

Obstructive sleep apnea (OSA) is characterized by intermittent cessation of breathing during sleep due to the collapse of oropharyngeal tissues. This review examines the role of craniofacial growth in OSA and evaluates the efficacy of orthodontic and orthognathic treatments. Maxillary expansion and orthognathic surgery have demonstrated significant reductions in sleep apneas and hypopneas, although they do not consistently achieve cure levels, particularly in the presence of obesity and connective tissue disorders.

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Finite element analysis of stress distribution in cantilever resin-bonded zirconia fixed dental prosthesis and periodontal tissue with alveolar bone loss.

J Prosthodont Res

January 2025

Department of Masticatory Function and Health Science, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Purpose: To compare the stress distribution in loaded zirconia resin-bonded fixed dental prostheses (RBFDPs) and periodontal tissue using finite element analysis, considering reduced alveolar bone levels and the number of retainers.

Methods: A human skull was micro-CT scanned. Three framework designs were tested: a 2-unit RBFDP using the maxillary left central incisor (#21) as an abutment, another using a canine (#23), and a 3-unit RBFDP using both #21 and #23.

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Assessing the need for specialty consultation for isolated medial orbital wall fractures.

Oral Surg Oral Med Oral Pathol Oral Radiol

October 2024

Oral & Maxillofacial Surgery Department, Boston Medical Center, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, USA.

Objective: This objective was to assess if the current practice of interfacility transfer and immediate specialty consult is justified by the rate of surgical repair for isolated medial orbital wall fractures.

Study Design: This is a retrospective descriptive study utilizing the records of all patients with isolated medial orbital wall fractures who presented to the ED at Boston Medical Center from January 2014 to December 2022. A descriptive analysis was completed.

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Importance: Caries is the most common chronic childhood disease, with substantial health disparities.

Objective: To test whether parent-targeted oral health text (OHT) messages outperform child wellness text (CWT) messages on pediatric caries increment and oral health behaviors among underserved children attending pediatric well-child visits.

Design, Setting, And Participants: The parallel randomized clinical trial, Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children (iSmile), included participants who were recruited during pediatric medical clinic visits at 4 sites in Boston, Massachusetts, that serve low-income and racially and ethnically diverse (herein, underserved) populations.

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Background: Smartphone apps can be used to monitor chronic conditions and offer opportunities for self-assessment conveniently at home. However, few digital studies include older adults.

Objective: We aim to describe a new electronic cohort of older adults embedded in the Framingham Heart Study including baseline smartphone survey return rates and survey completion rates by smartphone type (iPhone [Apple Inc] and Android [Google LLC] users).

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Background: Odontogenic cysts of the jaws are pathologies that require timely recognition and management. The initial diagnosis is based on clinical and radiographic appearance and dental history. A variety of surgical treatments are used for odontogenic keratocyst (OKC) depending on the clinical and radiographic presentation.

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Objectives: To explore physiotherapists' experiences and perceived acceptability of delivering a bracing intervention for knee osteoarthritis (OA) in the 'PROvision of braces for Patients with knee OA' (PROP OA) randomised controlled trial.

Method: Semi-structured telephone interviews with consenting physiotherapists who received the PROP OA training programme and delivered the knee bracing intervention (advice, information and exercise instruction plus knee brace matched to patients' clinical and radiographic presentation and with adherence support). Interviews were recorded and transcribed verbatim.

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Background: A Partial pulpotomy technique is an alternative choice of treatment for immature permanent teeth with exposed vital pulps. This study aimed to compare the histopathological pulpal response of the primary teeth of puppies after partial pulpotomy and full pulpotomy using mineral trioxide aggregate (MTA).

Materials And Methods: 72 primary premolars from experimental puppies aged 6-8 weeks were equally divided into test and control groups, as MTA partial pulpotomy (MTA-PP) and MTA full pulpotomy (MTA-FP).

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Patients' Preferences for the Treatment of a Single Missing Tooth in China: A Discrete Choice Experiment.

Patient Prefer Adherence

December 2024

Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong, People's Republic of China.

Article Synopsis
  • - The study explores preferences for restoring a single missing tooth using two main options: tooth-supported fixed partial dentures (FPDs) and implant-supported single crowns (ISCs) through a discrete choice experiment (DCE).
  • - Participants aged 18-60 completed a questionnaire focusing on five important treatment attributes: procedure, time, cost, five-year survival rate, and five-year complication rate; the analysis indicated that complication rates were deemed most important.
  • - Results showed participants were willing to pay significantly more for reduced complication rates, highlighting the importance of addressing this factor in dental treatments and improving communication between patients and dentists regarding their preferences.
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Author's Response.

J Am Dent Assoc

January 2025

General Dentist, Faculty, Henry M. Goldman School of Dental Medicine, Boston University, Boston, MA.

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Dental caries among long-term care (LTC) residents is a persistent and complex problem driven by social and structural factors. Systems thinking may be useful in considering novel approaches to reducing disease. This study aimed to develop a system dynamics model to simulate the progression of dentate older adults in LTC through caries severity states and estimate the effects of 3 intervention scenarios on the progression of caries: preventive topical fluoride (TF), arrest of caries with silver diamine fluoride (SDF), and a combination of TF and SDF.

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Article Synopsis
  • The study aimed to examine how patient characteristics and potential factors contribute to the occurrence of external cervical resorption (ECR) in teeth, analyzing 215 cases from a specialized dental practice in London.* -
  • Findings revealed that 22.3% of cases had no identifiable predisposing factors, while 57.7% had one factor (most commonly orthodontic treatment) and 20% had multiple factors, with significant variations based on patient demographics and tooth types.* -
  • Notably, males had a higher occurrence of sole predisposing factors compared to females, and the presence of dental trauma and pet ownership were among the most common factors linked to ECR.*
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B2M or CIITA knockdown decreased the alloimmune response of dental pulp stem cells: an in vitro study.

Stem Cell Res Ther

November 2024

Restorative Dental Sciences, Endodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong, SAR, China.

Article Synopsis
  • The study explores the potential of genetically modifying dental pulp stem cells (DPSCs) to reduce their immune response after transplantation, which is a significant barrier for their use in treating ischemic diseases.
  • Individual knockdowns of Beta 2-microglobulin (B2M) and class II histocompatibility complex transactivator (CIITA) were performed using lentiviral methods, showing that these modifications did not affect the stem cells' ability to self-renew or differentiate.
  • Results demonstrated that the modified DPSCs had lower immune system recognition and higher survival rates when exposed to immune challenges, suggesting genetic knockdowns could enhance the viability of DPSCs in therapeutic applications.
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Introduction: Hypoxic Ischemic Encephalopathy (HIE) is a birth complication due to loss of oxygen flow, resulting in a wide range of physical and cognitive differences often requiring support from multidisciplinary healthcare teams. Despite this population's increased need, little is known about their oral health status and the role of the dentist as a member of the care team.

Methods: A 32-item oral health questionnaire was shared to 8700 members within the patient advocacy non-profit, Hope for HIE's, Facebook group.

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Children exposed prenatally to antiepileptic drugs may have a typical facies characterized by midfacial retrusion, a short nose, and anteverted nares. Our aim was to determine whether the shape of the maxilla was altered in its sagittal displacement, or whether the defect in the underlying articulation with the cranial base was responsible for the appearance of midface retrusion. Our hypothesis was that the sphenoid bone as well as the maxilla and other bones in the cranial base were affected by the anticonvulsant medication.

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Feasibility of using two generative AI models for teeth reconstruction.

J Dent

December 2024

Department of Prosthetic Dentistry, Faculty of Medicine, Medical Center -University of Freiburg, Center for Dental Medicine, University of Freiburg, Freiburg, Germany.

Objectives: This feasibility study investigates the application of artificial intelligence (AI) models, specifically transformer-based (TM) and diffusion-based (DM) models, for the reconstruction of single and multiple missing teeth.

Methods: A dataset of 129 digitized models was utilized to create both TM and DM models. Single and multiple missing teeth were artificially generated.

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Effect Modification by Obesity on Nonsurgical Periodontal Treatment.

JDR Clin Trans Res

October 2024

Department of General Dentistry, Director of the Center for Clinical Research, and Department of Health Policy and Health Services Research, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.

Introduction: Obesity is associated with increased periodontal disease prevalence and incidence. This retrospective cohort study examined whether body mass index (BMI) is an effect modifier of periodontal treatment outcomes in patients attending an urban dental school clinic.

Methods: Data were extracted from electronic health records of 344 patients at a large urban dental school clinic who had at least 1 tooth with a probing pocket depth (PD) ≥5 mm at baseline and who subsequently received nonsurgical periodontal treatment.

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Background: Dental implants are an effective treatment option for edentulism, which poses a substantial barrier to oral health. The quality of the bone at the implant site may have an impact on the outcome of implant therapy. The purpose of this retrospective investigation was to assess implant survival rates and problems in individuals who were edentulous and had varying forms of bone.

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Background: By resolving the difficulties associated with missing teeth, implant-supported restorations have emerged as a key component of contemporary dentistry. The choice of prosthetic materials is crucial in establishing the durability and clinical efficacy of these restorations.

Methods: A prospective design was used at a tertiary care hospital with 150 patients receiving implant-supported restorations.

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Introduction: Literature demonstrates the detrimental impact of discrimination and microaggressions at personal and institutional levels in the health care workplace. Residents in our program requested curricula to help with addressing manifestations of bias. In response, we designed and implemented an adaptable and reproducible 4-hour virtual simulation session aimed at helping residents identify and constructively respond to microaggressions.

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Effect of machining damage on the surface roughness and flexural strength of CAD-CAM materials.

J Prosthet Dent

September 2024

Professor, Department of Restorative Sciences & Biomaterials, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Mass; Assistant Dean, Biomaterials & Biomaterials Research, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Mass; and Director, Biomaterials Research, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Mass.

Statement Of Problem: Computer-aided design and computer-aided manufacturing (CAD-CAM) materials are available for different types of restorations. However, the longevity of the material is affected by chipping, milling damage, flexural strength, and surface roughness, and a standard edge chipping test or standardized measurements are unavailable for monitoring edge chipping of rotary instrument-milled materials.

Purpose: The purpose of this in vitro study was to analyze the surface roughness and edge chipping of different CAD-CAM diamond rotary instrument-milled dental material bars, correlate the effect of machining damage with material strength, and compare the flexural strength of rotary instrument-milled and sectioned CAD-CAM blocks.

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Single-cell analysis of peri-implant gingival tissue to assess implant biocompatibility and immune response.

J Prosthodont Res

January 2025

Department of Dentistry, National Taiwan University Hospital & Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.

Purpose: The innate immune response, particularly the reaction of polymorphonuclear neutrophils (PMNs), is crucial in shaping the outcomes of chronic inflammation, fibrosis, or osseointegration following biomaterial implantation. Peri-implantitis or peri-implant mucositis, inflammatory conditions linked to dental implants, pose a significant threat to implant success. We developed a single-cell analysis approach using a murine model to assess the immune response to implant materials, offering a practical screening tool for potential dental implants.

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Response to Letter to the Editor regarding, "A method of fabricating a stackable CAD-CAM custom record tray for complete dentures".

J Prosthet Dent

November 2024

Clinical Assistant Professor, Department of General Dentistry, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Mass.

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