Synthesis and Structure of Uranium Disilyl-Substituted Alkylidene Complexes.

Understanding the participation of f-orbitals of actinide elements in covalent bond formations is less explored, compared to the well-studied d-orbitals of transition metals, leading to the significant interest in actinide-carbon multiple bonds. Uranium alkylidene complex, containing an alkylidene linkage of the form U═CR (R = H, alkyl, silyl), represents a key milestone in actinide-ligand multiple bonding, but their isolation and characterization have remained elusive. Herein, we present the synthesis of an unprecedented uranium disilyl-substituted alkylidene complex, achieved through sequential dehydrogenation reactions of a methyl group under mild conditions.

A study on the relationship between high school students' sleep quality, physical exercise, academic stress, and subjective well-being.

Objective: This Research explores the intermediary function of academic stress and sleep quality in the connection between physical exercise and subjective well-being among high school students.

Methods: This Research conducted an online survey through random sampling with a sample of 540 (males = 310, females = 217; grade 10 = 159, grade 11 = 190, grade 12 = 178) high school students to explore the intermediary function of academic stress and sleep quality between physical exercise and subjective well-being. The participants were surveyed using PSQI, the Subjective Well-Being Scale, the ESSA, and PSQI.

Preclinical application of a CD155 targeting chimeric antigen receptor T cell therapy for digestive system cancers.

Despite intensive multimodal therapy, the prognosis for patients with digestive system cancers remains poor. Cancer cell heterogeneity and immunosuppressive microenvironments are the main barriers to the effective CAR-T cell therapy with solid malignancies. In parallel, tumor-associated macrophages (TAMs) are essential for tumor immunosuppressive microenvironment formation.

Real time task planning for order picking in intelligent logistics warehousing.

With the rapid growth of e-commerce and ongoing innovations in the logistics industry, intelligent unmanned logistics warehousing systems have emerged to significantly enhance operational efficiency and reduce costs. In these systems, the two critical stages of order assignment and path planning are interconnected through racks in the order picking process. However, prior research has largely overlooked their joint optimization.

Visible-light-driven CO photoreduction over atomically strained indium sites in ambient air.

Strain engineering offers an attractive strategy for improving intrinsic catalytic performance of a heterogeneous catalyst. Herein, we successfully create strain into layered indium sulfide (InS) at atomic scale via introducing oxygen coordination and sulfur vacancy using a wet-chemistry method. The atomically strained InS exhibits greatly enhanced CO photoreduction performance, achieving a CO to CO conversion rate of 5.

Sensitive colorimetric sensing of dopamine and TYR based on enhanced HRP-like activity of CuNi/Fe LDHs nanozymes.

CuNi/Fe LDHs with HRP-like activity (nanozyme) have been prepared. Contrary to the expected design, free dopamine (DA) was found to greatly enhance the catalytic performances of CuNi/Fe LDHs nanozyme. As far as we know, this is the first report that free DA boosts the catalytic performances of LDHs.

Design, synthesis and activity evaluation of 4-(quinoline-2-yl)aniline derivatives as SARS-CoV‑2 main protease inhibitors.

Since 2020, numerous compounds have been investigated for their potential use in treating SARS-CoV-2 infections. By identifying the molecular targets during the virus replication process, rationally designed anti-SARS-CoV-2 agents are developed. Among these targets, the main protease (M) is a crucial enzyme required for virus replication, and its highly conserved characteristic make it an important drug target for the development of anti-SARS-CoV-2 drugs.

The relationship between professional identity and academic burnout among music education students: The mediating role of academic self-efficacy.

Background: Academic burnout is a common mental health issue among college students, particularly pronounced among students majoring in music education. Despite evidence that professional identity influences academic burnout, the mechanism of action remains unclear, particularly the relationship between academic self-efficacy and academic burnout. Furthermore, research specifically addressing the connection between professional identity and academic burnout among music majors is relatively limited.

Investigating automatic processing preference in high trait anxiety individuals: Behavioral and neuroelectrophysiological evidence.

The Trait Anxiety Attention Control Theory suggests an imbalance in high trait anxiety individuals between bottom-up and top-down processing. To investigate this theory, we designed an experimental paradigm combining task-switching and Stroop tasks to investigate behavioral and neuroelectrophysiological features in trait anxiety. The results revealed a significant negative correlation between trait anxiety levels and switch costs, indicating a preference for automatic processing among those with high trait anxiety.

Clinical Features and Surgical Procedures of Acquired Rectovestibular Fistula: A Single-center Retrospective Study.

Introduction: We reviewed a 7-year experience (Jan 2016 to Oct 2023) in diagnosing and surgically treating Acquired Rectovestibular Fistula (ARVF). Our study describes the medical history, introduces new classifications based on fistula features, and outlines the application of diverse surgical techniques in treating these patients.

Methods: A total of 78 girls with ARVF appeared asymptomatic at birth.

Red-emitting fluorescent probe with excellent water solubility for the in situ monitoring of endogenous HS in wheat under salt and Al stress.

Hydrogen sulfide (HS) is a pivotal signaling molecule in plants and appropriate levels are essential for normal growth. As such the real-time detection of HS in plants is required since it enables timely targeted interventions. However, most fluorescent probes for detecting HS reported to date exhibit fluorescence quenching in aqueous solution thereby significantly constraining their potential for in vivo applications.

Occurrence, spatial-seasonal variation and air-soil exchange of traditional and novel organochlorine pesticides across 30° latitude in Eastern China: Old tales and new realities.

While traditional organochlorine pesticides (OCPs) have been phased out under international regulations, novel OCPs are increasingly used as substitutes, however, their environmental behavior was not well clarified. Here, the first comprehensive study on the occurrence, seasonal-spatial variation, and air-soil exchange of both traditional and novel OCPs across a 30° latitudinal gradient (22°N to 52°N) in Eastern China were conducted. Air concentrations of ΣOCPs peaked during summer months, whereas soil concentrations were elevated in winter.

Enhanced Chemiluminescence Induced by Natural Light-Driven MIL-100(Fe)/TiO for Dopamine Detection.

Luminol-based chemiluminescence (CL) systems, as a powerful tool for bioanalysis, are limited owing to their weak CL intensity and self-decomposition of the classic oxidant HO. Herein, we introduced a new luminol CL enhancer, the natural light-driven photocatalyst MIL-100(Fe)/TiO, for the selective determination of dopamine (DA). By employing MIL-100(Fe)/TiO for the first time as an efficient enhancer, the MIL-100(Fe)/TiO-luminol CL intensity was 100 times higher than that of the classical HO-luminol system.

Nonmetallic High-Entropy-Engineered Nanocarbons for Advanced ORR Electrocatalysis.

High-entropy materials are poised to revolutionize materials science and industrial applications due to their design flexibility, peculiar performance, and broad applicability. In this study, we present a proof-of-concept high-entropy engineered nanocarbon (HENC) co-doped with five nonmetal elements (B, F, P, S, and N), synthesized via in situ polymerization modification of ZIF-8 followed by pyrolysis. The HENC exhibits outstanding performance as a nonmetal electrocatalyst for the oxygen reduction reaction (ORR), with activity on par with benchmark Pt/C electrocatalysts and superior cyclic stability.

Molecular evolution of dietary shifts in ladybird beetles (Coleoptera: Coccinellidae): from fungivory to carnivory and herbivory.

Background: Dietary shifts are major evolutionary steps that shape ecological niches and biodiversity. The beetle family Coccinellidae, commonly known as ladybirds, first transitioned from a fungivorous to an insectivorous and subsequently a plant diet. However, the molecular basis of this dietary diversification remained unexplored.

The effect of induced molting on the testicular physiological remodeling in no-semen roosters.

Background: The fertility of roosters significantly impacts the economic outcome of the poultry industry. However, it is common for some roosters to fail to produce semen during production, and the underlying reasons remain largely unclear.

Results: To investigate a solution to this problem, induced molting (IM) was performed on no-semen (NS) roosters.

A case of a neonatal cardiac tumor with ventricular tachycardia undergoing emergency surgery.

Background: Cardiac tumors in children are rare and usually have no obvious clinical symptoms. However, a small number of children may experience serious conditions such as arrhythmia, heart obstruction, and even death. When severe arrhythmia cannot be controlled by conservative treatment, surgical intervention is needed.

FDEM numerical simulation of size effect on mechanical properties of basalts with hidden microcracks.

As an important geological environment medium for engineering construction in southwest China, basalt generally contains hidden microcracks at a micro-scale, which leads to significant size effect on its mechanical properties, and relevant research is lacking and unsystematic. A synthetic rock mass model based on the combination of a micro-discrete fracture network method and a finite-discrete element method is used to systematically explore the size effect of the mechanical properties of basalt rock blocks with hidden microcracks. The results showed that: (1) the fracture angle is uniformly distributed, and the fracture length conforms to the logarithmic normal distribution, with an areal fracture intensity P20 of 0.

Differential roles of IL-17B and IL-17RB in colorectal cancer: Correlation with immune infiltration and prognosis.

Background: The aim of the research is to investigate correlation of immune infiltration between IL-17B and IL-17RB in colorectal cancer (CRC), then provide an experimental basis for clinical diagnostic marker screening of CRC.

Methods: Gene expression levels were assessed via TIMER and GEPIA databases, protein expression through the Human Protein Atlas (HPA), clinicopathological correlations and prognosis via UALCAN and KM-Plotter, respectively. Mutation analysis was conducted using cBioPortal, immune cell infiltration via TIMER, and hub genes were identified through protein-protein interaction (PPI) networks.

Impact of the potassium transporter TaHAK18 on wheat growth and potassium uptake under stressful K conditions.

Potassium (K), an indispensable nutrient for plant growth and development, plays a crucial role in plant stress resistance. Within the K regulatory network in plants, the HAK/KUP/KT gene family comprises a dominant group of K transport proteins responsible for K uptake and transport. This study functionally characterized the wheat gene TaHAK18, which encodes a putative K transporter.

A plant virus manipulates both its host plant and the insect that facilitates its transmission.

Tomato yellow leaf curl virus (TYLCV), a devastating pathogen of tomato crops, is vectored by the whitefly , yet the mechanisms underlying TYLVC epidemics are poorly understood. We found that TYLCV triggers the up-regulation of two β-myrcene biosynthesis genes in tomato, leading to the attraction of nonviruliferous . We also identified BtMEDOR6 as a key whitefly olfactory receptor of β-myrcene involved in the distinct preference of MED for TYLCV-infected plants.

Structural design of memory system for Ternary Optical Computer.

Ternary Optical Computer (TOC) is unique in the development of optical computers, in terms of principle, experiment, algorithm and application. After 20 years of development, six generations of prototypes have been developed. At present, tri-state optical signal storage is the main problem faced by TOC.

Copper(I)-Catalyzed Asymmetric α-Selenenylation of 2-Acylimidazoles.

A general method for the catalytic asymmetric α-selenenylation of simple carbonyl compounds is lacking. Herein, a copper(I)-catalyzed enantioselective α-selenenylation of 2-acylimidazoles with electrophilic selenosulfonates is uncovered. The reaction enjoys the advantages of mild conditions, easy reaction protocol, and broad substrate scopes on both 2-acylimidazoles and selenosulfonates.

Balancing Electronic Spin State via Atomically-Dispersed Heteronuclear Fe-Co Pairs for High-Performance Sodium-Sulfur Batteries.

Room-temperature sodium-sulfur (Na-S) batteries are emerging as a promising next-generation energy storage technology, offering high energy densities at low cost and utilizing abundant elements. However, their practical application is hindered by the shuttle effect of sodium-polysulfides and the sluggish kinetics of sulfur redox reactions. In this study, we demonstrate a heteronuclear diatomic catalyst featuring Fe and Co bimetallic sites embedded in nitrogen-doped hollow carbon nanospheres (Fe-Co/NC) as an effective sulfur host at the cathode of Na-S batteries.

What predicts mental health profiles in first-generation college freshmen?: the role of proactive personality and university environment.

Background: The mental health of first-generation college students has received much attention from researchers. The dual-factor model of mental health emphasizes the integration of psychopathology and well-being to achieve a comprehensive assessment of mental health. Previous research has focused on the psychopathology and well-being of first-generation college students in isolation while ignoring the overall mental health development.