34 results match your criteria: "Hematology and Oncology Training and Research Hospital[Affiliation]"

Clinical Evaluation of Balance in Children With Hemophilic Arthropathy.

Indian J Hematol Blood Transfus

October 2022

Pediatric Hematology/Oncology, Ankara Child Health and Diseases Hematology and Oncology Training and Research Hospital, University of Health Sciences, Ziraat Mah. Irfan Bastug Cd. Kurtdereli Sk. No: 10, 06110 Ankara, Turkey.

Purpose: Hemophilia is a hereditary coagulation disorder characterized by acute hemorrhages into the musculoskeletal system, leading eventually to arthropathy and disability. Chronic inflammation of the synovial membrane arises as a result of frequent joint hemorrhage. Proteolytic enzymes in the blood and cartilage cause deterioration after that, and joint space narrows.

View Article and Find Full Text PDF
Article Synopsis
  • - The study explored the link between FMF mutations and inflammatory bowel disease (IBD) in children, examining 597 pediatric patients with conditions like ulcerative colitis (UC) and Crohn's disease (CD).
  • - Results revealed that 41.9% of patients had FMF mutations, with E148Q and M694V being the most common mutations associated with different types of IBD, and differences in disease characteristics were noted based on mutation types.
  • - The findings suggested that while FMF mutations appeared relevant in UC (showing lower disease activity scores), they did not significantly affect the inflammatory response or clinical outcomes in patients with IBD overall, particularly those with CD.
View Article and Find Full Text PDF

Aim: In Turkey, improvements in sanitation and the implementation of a vaccination program resulted in reduced rates of childhood exposure to hepatitis A virus. The incidence of symptoms and the complications of the disease are known to be increased in later ages. We aimed to describe changes in the seroprevalence of hepatitis A virus from the pre-vaccine era (2012) to the post-vaccine era (2018) in different age groups.

View Article and Find Full Text PDF

Introduction: This study determined whether there is a difference in the nutritional status of children with good and poor appetites, as reported by their mothers.

Methods: In all, 70 volunteer mothers of children aged 6-60 months participated in the study. Information about the nutrition of the child was obtained from the mothers via a questionnaire.

View Article and Find Full Text PDF

Aim: The main purpose of this study is to determine the current status of long-term follow-up (LTFU) for childhood cancer survivors and the challenges of LTFU for pediatric cancer survivors at pediatric oncology institutions in Turkey.

Material And Methods: A questionnaire was e-mailed to the directors of 33 pediatric oncology centers (POCs) registered in the Turkish Pediatric Oncology Group (TPOG). Of these 33 active TPOG institutions, 21 participated in the study and returned their completed questionnaires.

View Article and Find Full Text PDF

Değerliyurt A, Gezgen Kesen G, Ceylaner S. Ataxia, tremor, intellectual disability: a case of STXBP1 encephalopathy with a new mutation. Turk J Pediatr 2019; 61: 757-759.

View Article and Find Full Text PDF

Objective: Continued progress in our understanding of the food protein-induced allergic proctocolitis (FPIAP) will provide the development of diagnostic tests and treatments. We aimed to identify precisely the clinical features and natural course of the disease in a large group of patients. Also, we investigated the predicting risk factors for persistent course since influencing parameters has not yet been established.

View Article and Find Full Text PDF

Elmaoğulları S, Yıldız AE, Demir S, Gürkan H, Uçaktürk SA. A novel LEMD3 pathogenic variant in a son and mother with osteopoikilosis. Turk J Pediatr 2019; 61: 594-598.

View Article and Find Full Text PDF

Background: Recurrent aphthous stomatitis (RAS) is one of the most common diseases of the oral mucosa and may be related to vitamin deficiencies or systemic diseases such as celiac disease (CD). The aim of this study was to investigate the frequency of hematinic deficiency and CD in children with RAS.

Methods: The medical records of patients diagnosed with RAS were reviewed for the presence of hematinic deficiencies (hemoglobin, mean corpuscular volume, ferritin, vitamin B , folic acid), and CD.

View Article and Find Full Text PDF

Background And Aims: Internet use has increased worldwide exponentially over the past two decades, with no up-to-date cross-country comparison of Problematic Internet Use (PIU) and its correlates available. The present study aimed to explore the pattern and correlates of PIU across different countries in the European and the Asian continent. Further, the stability of factors associated with PIU across different countries were assessed.

View Article and Find Full Text PDF

Sounds unrealistic: an adolescent girl with anorexia nervosa consumes 19 L of fluid in a few hours: what happens to the physiology?

Eat Weight Disord

October 2020

Department of Pediatrics, Division of Adolescent Medicine, Hacettepe University Ihsan Dogramaci Children's Hospital, Hacettepe University School of Medicine, Ankara, Turkey.

Background: Adolescents with eating disorders (EDs) may present not only with abnormal eating behaviors but also with abnormal drinking behaviors varying widely. These behaviors include water loading to cheat on weight measurements, to feel full and suppress appetite and/or to induce vomiting; as well as restricting fluid intake in addition to food.

Method: We present a 16-year-old female adolescent with anorexia nervosa restrictive type and major depressive disorder who was hospitalized due to acute food refusal and developed generalized seizures due to dilutional hyponatremia in consequence of consuming excessive amount of water.

View Article and Find Full Text PDF

Effects of 5-Hydroxymethylfurfural on Pubertal Development of Female Wistar Rats.

J Clin Res Pediatr Endocrinol

March 2020

University of Health Sciences Turkey, Dr. Sami Ulus Children Training and Research Hospital, Clinic of Pediatric Endocrinology, Ankara, Turkey

Objective: 5-Hydroxymethylfurfural (HMF) is formed when sugars are heated in the presence of amino acids. HMF is naturally present in many foods. To investigate the toxic effects of HMF on the reproductive system of peripubertal rats.

View Article and Find Full Text PDF

A variety of conditions may affect the trigeminal nerve. Magnetic resonance imaging is the modality of choice when trigeminal nerve pathology is suspected, and this modality plays an essential role in detecting causes. This review illustrates some of the pathological conditions relevant to the trigeminal nerve in magnetic resonance imaging.

View Article and Find Full Text PDF

Introduction:  Detecting renal scar is important in pediatric patients with vesicoureteral reflux (VUR) for deciding on treatment option. The aim of this study is to detect whether freehand elastosonography technique could be an alternative to dimercaptosuccinic acid (DMSA) scan in determining renal scar formation.

Materials And Methods:  Between November 2015 and April 2016, 25 VUR patients, age ranging from 3 to 17 years admitted to our clinic, had urinary ultrasound and elastosonography, and data of approximately 147 renal region were recorded.

View Article and Find Full Text PDF

Background And Aim: Autoimmune hemolytic anemia (AIHA) is characterized by autoimmune destruction of erythrocytes. In this retrospective study, the clinical, laboratory features and treatment responses of patients with primary AIHA were evaluated.

Material And Methods: 21 consecutive patients diagnosed with primary AIHA in a children's hospital from 2008 to 2016 were included.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess the prevalence of affective disorders in a representative sample of Turkish students from second to fourth grades.
  • A total of 5,842 participants were analyzed, revealing a 2.5% prevalence of affective disorders, with major depressive disorder (MDD) being the most common at 1.06%.
  • The findings suggest the need for early interventions, particularly for children with family risk factors like maternal psychopathology and paternal illness.
View Article and Find Full Text PDF

Altan H, Budakoğlu Iİ, Şahin-Dağlı F, Oral R. Measuring awareness about child abuse and neglect: Validity and reliability of a newly developed tool-child abuse and neglect awareness scale. Turk J Pediatr 2018; 60: 392-399.

View Article and Find Full Text PDF

Objective: Zinc transporter 8 protein (ZnT8A) is a transmembrane protein which functions to transfer zinc to insulin vesicles. Antibodies formed against ZnT8A (ZnT8A) are regarded as an independent autoimmunity demonstrator in type 1 diabetes (T1D). The aim of this study was to investigate the prevalence of ZnT8A in Turkish children with new onset T1D.

View Article and Find Full Text PDF

Background: Brugada syndrome is an inherited arrhythmogenic disease that may cause sudden cardiac death due to ventricular fibrillation in young adults. Brugada syndrome caused by propafenone intoxication has been noted rarely in the literature. We report a rare case, Brugada phenocopy due to propafenone intoxication and its treatment.

View Article and Find Full Text PDF

Objective: This study aimed to define the status of juvenile myelomonocytic leukemia (JMML) patients in Turkey in terms of time of diagnosis, clinical characteristics, mutational studies, clinical course, and treatment strategies.

Materials And Methods: Data including clinical and laboratory characteristics and treatment strategies of JMML patients were collected retrospectively from pediatric hematology-oncology centers in Turkey.

Results: Sixty-five children with JMML diagnosed between 2002 and 2016 in 18 institutions throughout Turkey were enrolled in the study.

View Article and Find Full Text PDF

Why Fever Phobia Is Still Common?

Iran Red Crescent Med J

August 2016

Department of Pediatrics, Turgut Ozal University, Ankara, Turkey.

Background: Fever is a reliable sign of illness, but it also evokes fear and anxiety. It is not the fever itself but the fear of possible complications and accompanying symptoms that is important for pediatricians and parents.

Objectives: We aimed to investigate maternal understanding of fever, its potential consequences, and impacts on the treatment of children.

View Article and Find Full Text PDF

Purpose: In this study, we retrospectively investigated case reports with and without midazolam administration via oral, intranasal and rectal before cystometry procedure. We aimed to compare the data to evaluate the effects of sedation before cystometry on the pediatric patients and parents' satisfaction.

Methods: A total of 124 ASA I-II pediatric cases aged 5-14 years were retrospectively investigated from the hospital records.

View Article and Find Full Text PDF

Focal Nodulary Hyperplasia of the Liver Due to Congenital Portosystemic Shunt: A Rare Condition Mimicking Hepatocellulary Carcinoma.

J Pediatr Hematol Oncol

January 2017

Departments of *Pediatric Hematology and Oncology †Pediatric Cardiology §Pathology, Ankara Pediatric Hematology and Oncology Training and Research Hospital ‡Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, 06110 Ankara, Turkey.

Congenital portosystemic shunts are rare vascular malformations that lead to several complications including liver tumors, pulmonary hypertension, and metabolic encephalopathy. We describe a rare case of a 17-year-old girl with an extrahepatic portosystemic shunt presenting recurrent syncope episodes and a liver mass mimicking hepatocellulary carcinoma.

View Article and Find Full Text PDF