Intranodal Hemangioma: Case Report and Systematic Review.

Background: Intranodal hemangiomas are rare benign vascular tumors of the lymph nodes, often misdiagnosed as malignant lymphadenopathies due to their clinical and radiological features. This case report and systematic review aim to elucidate the epidemiology, clinical profile, and therapeutic interventions for intranodal hemangioma, enhancing diagnostic accuracy and management.

Methods: A systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Acteoside relieves diabetic retinopathy through the inhibition of Müller cell reactive hyperplasia by regulating TXNIP and mediating Kir4.1 channels in a PI3K/Akt-dependent manner.

Diabetic retinopathy (DR) is a severe microangiopathy of diabetes. Müller cells play an important role in the development of DR. Acteoside (ACT) has been reported to be effective in the treatment of DR.

Efficacy and safety of oral propranolol and topical timolol in the treatment of infantile hemangioma: a meta-analysis and systematic review.

Background: Propranolol, a nonselective β-blocker, is the first-line treatment for infantile hemangioma (IH). Topical timolol has recently been proposed as a novel IH treatment with fewer adverse effects. This study was conducted to compare the efficacy and safety of oral propranolol and topical timolol for treating IH.

A novel three-dimensional model of Infantile Haemangioma.

Infantile Haemangioma (IH) is vascular tumour in infants exhibiting rapid proliferation and angiogenesis followed by gradual involution.10% of cases are associated with disfiguring complications and requires medical interventions with β-blockers such as propranolol, surgery, or laser therapy. An in vitro IH three-dimensional (3D) model will improve our understanding of the disease mechanism(s).

The 595-nm Wavelength Pulsed Dye Laser for Pediatric Port-Wine Birthmarks and Infantile Hemangiomas: A Systematic Review.

Introduction: The 595-nm wavelength pulsed dye laser (PDL) is well-established in the treatment of vascular lesions. In June 2023, it received FDA clearance for the treatment of port-wine birthmarks (PWB) and infantile hemangiomas (IH) in the pediatric population.

Objective: Review the evidence regarding the efficacy, safety, and implications of using PDL for management of pediatric PWB and IH.

Prognostic utility of gamma-glutamyl transpeptidase to platelet ratio in patients with solitary hepatitis B virus-related hepatocellular carcinoma after hepatectomy.

Background: The prognostic impact of preoperative gamma-glutamyl transpeptidase to platelet ratio (GPR) levels in patients with solitary hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) following radical resection has not been established.

Aim: To examine the clinical utility of GPR for prognosis prediction in solitary HBV-related HCC patients.

Methods: A total of 1167 solitary HBV-related HCC patients were retrospectively analyzed.

Infantile Hemangioma Localized in the Levator Aponeurosis-Müller's Muscle Complex.

A two-month-old male infant presented with a soft palpable mass on his left upper eyelid. Initial management consisted of watchful observation followed by administration of β-blocker eyedrops on the eight-month check-up when a purple subconjunctival mass was observed during eyelid eversion, suggestive of an infantile hemangioma. At the three-year follow-up, since it was observed that the treatment did not reduce the size of the mass, an excisional biopsy was performed at the request of the mother.

[Stereotactic radiotherapy of spinal hemangioblastoma].

Hemangioblastoma (HAB) is a benign, richly vascularized tumor that accounts for 2-6% of all spinal cord neoplasms and ranks third in the structure of intramedullary space-occupying lesions of the spinal cord. Hemangioblastoma may occur sporadically or, in approximately 30% of cases, as part of the clinical picture of a hereditary disease, von Hippel-Lindau disease. The aim of this study was to evaluate the efficacy and safety of stereotactic irradiation of hemangioblastomas of the spinal localization in patients with sporadic and von Hippel-Lindau-associated hemangioblastomas The results of stereotactic radiotherapy were evaluation of 210 spinal hemangioblastomas in 74 patients.

Intraosseous Hemangioma of the Iliac Bone: An Incidental Finding Mimicking Metastatic Disease.

Intraosseous hemangiomas are rare benign vascular tumors predominantly occurring in the axial skeleton. This case report describes a 44-year-old female with a history of multiple renal stones and benign breast calcifications, who was incidentally found to have a 1.2 cm lucent lesion in the left iliac bone during imaging for nephrolithiasis.

Macular edema in Wyburn-Mason syndrome: Resolution with anti-VEGF intravitreal injections. Case report and review of the literature.

Purpose: Macular edema is an infrequent complication of retinal arteriovenous malformations. We present the management of unilateral macular edema with Bevacizumab 1.25mg/0.

Intravitreal bevacizumab for the treatment of choroidal haemangiomas.

Purpose: To investigate the use of intravitreal bevacizumab for the treatment of subretinal (SRF) and intraretinal fluid associated with circumscribed choroidal haemangiomas (CCH).

Methods: This was a retrospective review of all patients treated with at least 3 bevacizumab injections for CCH-associated SRF between May 2020 and August 2023 in Moorfields eye hospital. Outcome measures included change in best corrected visual acuity (BCVA), change in patient reported symptoms, change in SRF and change in central subfield thickness (CSFT).

Retinal Racemosal Hemangioma Associated with Intracranial Vascular Malformation (Wyburn -Mason Syndrome) - Case Report.

Purpose: To describe a case of Wyburn-Mason syndrome in a young child with initially declined treatment leading to delayed intervention.

Methodology: Case report.

Results: We report a 6-year-old boy with mild periocular trauma following a fall, who was incidentally found to have a retinal arteriovenous malformation (AVM) associated with a brain AVM, indicative of Wyburn-Mason Syndrome.

[Sclerosing pneumocytoma: an old disease with a rare presentation].

Pulmonary pneumocytoma, formerly known as sclerosing hemangioma, is a rare, benign tumor that frequently affects women in the 4th and 5th decades of life. Here we present the case of a 17-year-old patient with a diagnosis of sclerosing pneumocytoma with infrequent presentation.

Patient-reported outcomes in conservatively managed cerebral cavernous malformations.

Background: There is a paucity of studies on patient-reported outcomes and quality of life (QoL) in conservatively managed patients with a cerebral cavernous malformation (CCM).

Methods: This single-center observational study included consecutive adult CCM patients, diagnosed in 2000-2023, managed conservatively, and with at least 6 months of follow-up. Patients completed two validated patient-reported outcome measures (PROMs): EuroQol 5-dimensions 5-levels (EQ-5D-5L), and Patient-Reported Outcome Measurement Information System 29 (PROMIS-29).

Erratum: Transarterial embolization in neonatal Kasabach-Merritt syndrome.

[This corrects the article DOI: 10.3389/fped.2021.

A Rare Case With a Review of Cutaneous Composite Hemangioendothelioma and the Role of Neuroendocrine Markers.

Composite hemangioendothelioma comprises permutations of different histological patterns few of which have been found to have specific genetic alteration and immunohistochemical expression. It comprises retiform or epithelioid hemangioendothelioma-like areas, with a variable proportion of hemangioma or low-grade angiosarcoma-like areas. It was found to express neuroendocrine markers and was seen to have a worse prognosis in recurrence or distant metastasis.

Mechanism of miR-503-5p on cardiac hemangioma and clinical validation.

It has been claimed that microRNA 503-5p (miR-503-5p) is the key to the future diagnosis and treatment of cardiac hemangioma (CH), but the relationship between the two has not been fully validated. In this study, we analyzed the effect of miR-503-5p targeting type IA bone morphogenetic protein receptor (BMPR1A) on CH to inform future diagnosis and treatment of CH. First, miR-503-5p and BMPR1A abnormal expression sequences (vectors) were transfected into human hemangioma-derived endothelial cells (HemECs) and human umbilical vein endothelial cells (HUVECs) to observe alterations in cell biological behavior, adhesion, and epithelial mesenchymal transition (EMT).

CT and MRI features of adrenal hemangioma: A study of 21 cases from two centers.

Purpose: To retrospectively analyze the CT and MR imaging presentations of adrenal hemangioma (AH) and to strengthen the recognition for such tumors.

Materials And Methods: This retrospective study enrolled 21 patients with 22 lesions histologically proven AH from two centers between October 2010 and November 2023. The clinical presentation and preoperative diagnosis were recorded.