281 results match your criteria: "Hellenic Red Cross Hospital[Affiliation]"

Article Synopsis
  • Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder among reproductive-age women, linked to obesity and insulin resistance, leading to mood disorders like anxiety and depression.
  • Women with PCOS often face low self-esteem due to physical symptoms like obesity, acne, and hirsutism, causing food cravings and binge eating.
  • Treatments for PCOS focus on lifestyle changes (diet and exercise), psychological support (like cognitive-behavioral therapy), and medical options such as GLP-1 analogs and naltrexone/bupropion to improve appetite regulation and mitigate the negative cycle.
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This case report aims to elucidate the current practices and efficacy of endovascular repair in managing splenic artery aneurysms (SAAs), particularly focusing on a case of a large, partially ruptured SAA. A 66-year-old female presented with severe abdominal pain and was later diagnosed with a 53mm saccular, degenerative SAA showing signs of partial rupture. The patient underwent successful endovascular repair using a combination of interlocking detachable coils and fibered coils.

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Early onset type 2 diabetes mellitus: an update.

Endocrine

September 2024

Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

The incidence and prevalence of type 2 diabetes mellitus (T2DM) in young individuals (aged <40 years) have significantly increased in recent years, approximating two to threefold increase in the respective rates. Numerous risk factors including severe obesity, family history, ethnicity, maternal diabetes or gestational diabetes, and female sex contribute to a younger age of onset. In terms of pathogenesis, impaired insulin secretion is the key operating mechanism, alongside with ectopic adiposity-related insulin resistance.

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Due to the extensive collateral arterial network, symptomatic chronic mesenteric ischemia is a relatively uncommon condition and is associated with severe atherosclerotic disease of all major visceral arteries. Open surgical repair has been commonly used to restore blood supply to the visceral arteries, and the "roof-top" approach has been advocated as an alternative technique to traditional midline incision, mainly because of the great exposure of the suprarenal aorta that it offers. Roof-top approach, in other words, bilateral subcostal incision, is a totally abdominal approach to the suprarenal aorta, and as the title says, it is like a roof-top on the abdominal wall.

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Background: Emergency coronary artery bypass surgery (eCABG) is a serious complication of chronic total occlusion (CTO) percutaneous coronary artery intervention (PCI).

Methods: We examined the incidence and outcomes eCABG among 14,512 CTO PCIs performed between 2012 and 2023 in a large multicenter registry.

Results: The incidence of eCABG was 0.

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Fistula formation between the urinary tract and the arterial system is very rare, and usually involves the ureter and the adjacent iliac vessels. Communication of the ureter with the aorta has been described a few times worldwide, and most of them had a fatal outcome. In our case, a 79-year-old man had a history of total cystectomy for malignancy and diversion of both ureters to a single site in the right hypogastrium with the left one crossing over the aorta.

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Hypothyroidism is common, however, aspects of its treatment remain controversial. Our survey aimed at documenting treatment choices of European thyroid specialists and exploring how patients' persistent symptoms, clinician demographics, and geo-economic factors relate to treatment choices. Seventeen thousand two hundred forty-seven thyroid specialists from 28 countries were invited to participate in an online questionnaire survey.

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A complete configuration of the circle of Willis is not always present, and anatomical variations are observed often. The fetal posterior cerebral artery has been described in cases where the embryonic posterior communicating artery has failed to regress, something that may happen on the right side, the left side, or bilaterally. We describe a case of a male patient with bilateral posterior cerebral arteries with direct communication with the internal carotid artery on both sides who presented with symptoms of stroke allocated to both posterior and middle cerebral artery areas.

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Comparing the performance of different continuous glucose monitoring (CGM) systems is challenging due to the lack of comprehensive guidelines for clinical study design. In particular, the absence of concise requirements for the distribution of comparator (reference) blood glucose (BG) concentrations and their rate of change (RoC) that are used to evaluate CGM performance, impairs comparability. For this article, several experts in the field of CGM performance testing have collaborated to propose characteristics of the distribution of comparator measurements that should be collected during CGM performance testing.

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Background/aim: Cystic nephroma (CN) is a very rare, benign, renal cystic lesion, which is characterized by a usually unilateral, multicystic kidney mass. In adults it is seen more frequently in females (1:8 male-to-female ratio). The peak incidence of CN is between 50 and 60 years of age.

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Objective: Late rupture after endovascular aortic aneurysm repair (EVAR) for an abdominal aortic aneurysm (AAA) is an increasing complication associated with a high mortality rate. This study aimed to analyse the causes and outcomes in patients with AAA rupture after EVAR.

Methods: A multi-institutional Greek study of late ruptures after EVAR between 2008 - 2022 was performed.

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Cardiac disease in Cushing's syndrome. Emphasis on the role of cardiovascular magnetic resonance imaging.

Endocrine

March 2024

University Research Institute of Maternal and Child Health and Precision Medicine and UNESCO Chair in Adolescent Health Care, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, Athens, Greece.

Article Synopsis
  • - Cushing's Syndrome (CS) significantly raises the risk of cardiovascular issues even after treatment, with heightened mortality and morbidity linked to both endogenous and exogenous types of the condition.
  • - The study reviews the underlying mechanisms of cardiac disease in CS, noting factors like glucocorticoid effects, arterial stiffness, and obesity, which contribute to various heart conditions that can persist after hypercortisolism is treated.
  • - Advanced imaging techniques, particularly cardiac magnetic resonance (CMR), are essential for assessing heart health in CS patients, revealing problems like left ventricular hypertrophy and microvascular disease that are often overlooked by standard echocardiography.
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Arterial entrapment syndrome (AES) at the elbow level is very rare. In cases of acute upper extremity ischaemia presenting in middle-aged patients with evident muscular hypertrophy, AES should always be included in the differential diagnosis. A thorough clinical examination should always follow, particularly when symptoms appear after reported strenuous upper extremity activity, and emergent surgical decompression is mandatory to avoid thrombotic complications in the affected arm in the future.

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Introduction: Thyroid specialists influence how hypothyroid patients are treated, including patients managed in primary care. Given that physician characteristics influence patient care, this study aimed to explore thyroid specialist profiles and associations with geo-economic factors.

Methods: Thyroid specialists from 28 countries were invited to respond to a questionnaire, Treatment of Hypothyroidism in Europe by Specialists: an International Survey (THESIS).

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Although tuberculosis (TB) is considered to be a common disease confined to undeveloped or developing countries, it may also appear in countries that accept great migrant influx from endemic areas. In terms of the skeletal system, it can be involved in 1-6% of tuberculosis patients while the knee joint is the third most frequently affected site after spine and hip. Given that systemic symptoms are present in only one-third of patients with skeletal tuberculosis and secondary septic arthritis, TB is often indolent and diagnosis can hence be missed or delayed.

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Article Synopsis
  • Intravascular lithotripsy (IVL) is being used more to treat calcification in stents, although it's considered an 'off-label' use.
  • A study of 101 patients from five European centers found that IVL significantly improved vessel narrowing and lumen area both when used immediately and later for stent failure.
  • The rates of major adverse cardiac events (MACE) were low after the procedure, suggesting IVL is a safe and effective option for managing calcification in stented patients.
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The purpose of this article is to report a case of bilateral foveal hypoplasia in an eight-year-old girl who presented to the ophthalmology department due to poor vision in both eyes. Clinical examination revealed bilateral nystagmus, decreased vision, as well as iris transillumination. Dilated fundus examination indicated the absence of light reflex around the foveal area and optical coherence tomography (OCT) imaging exhibited the absence of the fovea centralis depression.

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The Ageing Foot.

Int J Low Extrem Wounds

September 2023

Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Article Synopsis
  • Feet experience significant stress over a lifetime, leading to issues like dry skin, calluses, and infections, as well as degenerative conditions affecting ligaments and tendons.* -
  • Age-related foot problems can lead to deformities such as bunions, hammer toes, and stress fractures, which may decrease overall quality of life.* -
  • The review emphasizes the importance of prevention, foot care, and prompt treatment in maintaining foot health, which is crucial for overall well-being and mobility in older adults.*
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Premature Ovarian Insufficiency (POI) is a multi-factorial disorder that affects women of reproductive age. The condition is characterized by the loss of ovarian function before the age of 40 years and several factors have been identified to be implicated in its pathogenesis. Remarkably though, at least 50% of women have remaining follicles in their ovaries after the development of ovarian insufficiency.

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Article Synopsis
  • * The hypermetabolic state driven by adrenaline and noradrenaline leads to insulin resistance and impaired insulin secretion, with different tumor phenotypes causing distinct glycemic issues—mainly insulin resistance in adrenergic tumors and enhanced secretion in noradrenergic tumors.
  • * Surgical removal of PPGLs shows a high remission rate for secondary DM (up to 80%), suggesting hormonal co-secretion may play a role, and highlighting the need for more research into the management of DM in these patients,
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The bovine artery is considered the most frequent aortic arch branching variation. Despite being considered a normal variation of the aortic arch branching, still it has been linked with various issues regarding the thoracic aorta. The aim of this study is to highlight the prevalence of bovine artery among specific vascular pathologies throughout the literature and to provide information to clinicians about the importance of identifying this variation.

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Purpose: Cardiovascular disease is commonly accompanied by renal dysfunction. Multimorbidity in hospitalized patients impacts unfavorably on prognosis and hospital stay. We aimed to illustrate the contemporary burden of cardiorenal morbidity across inpatient cardiology care in Greece.

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Purpose: The aim of this study was to evaluate and compare the changes in Intraocular Pressure (IOP) and other ocular parameters: the Anterior Chamber Angle (ACA), Anterior Chamber Volume (ACV), and Anterior Chamber Depth (ACD) during phacoemulsification surgery in Greek patients with normotensive eyes and those with well-controlled Open-Angle Glaucoma (OAG). Additionally, parameters such as the Corneal Thickness (CCT), Axial Length (AL), Central Macular Thickness (CMT), and Retinal Nerve Fibre Layer (RNFL) were also examined.

Patients And Methods: This was a prospective observational case-control study that included 50 phakic eyes, 25 normotensive (Group 1), and 25 with OAG: 15 Primary Open-Angle Glaucoma (POAG) and 10 Exfoliation Glaucoma (EXG) (Group 2).

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The Impact of COVID-19 Pandemic in Orthopaedic Surgery Hospital Admissions and Workload in a Major Trauma Center.

J Long Term Eff Med Implants

April 2023

Pharmaceutical Studies & Research Division, Clinical Trials Department, National Organization for Medicines, Athens, Greece; School of Medicine, National and Kapodestrian University of Athens, Greece; Department of Anatomy and Surgical Anatomy, Medical School of National and Kapodistrian University of Athens.

The coronavirus disease 2019 (COVID-19) pandemic has led to important restrictions in social life of civilians worldwide and there were lower admission rates mainly in surgical departments in many hospitals. This study presents how COVID-19 pandemic affected admissions at the orthopaedic and trauma surgery department of a major trauma center. A retrospective study was conducted that recorded all patients examined at the outpatient orthopaedic clinic and the emergency orthopaedic department, as well as patients admitted to the orthopaedic surgery clinic and patients that underwent operative procedures between March 23 and May 4, 2020 (first lockdown period) and between March 23 and May 4, 2019 (control period).

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Secondary diabetes mellitus (DM) is a common complication of acromegaly, encountered in up to 55% of cases. Vice versa, the prevalence of acromegaly is markedly higher in cohorts of patients with type 2 DM (T2DM). The presence of secondary DM depends primarily on acromegaly status and is associated with increased cardiovascular morbidity, malignancy rate and overall mortality.

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