962 results match your criteria: "Hellenic Mediterranean University Research & Innovation Center[Affiliation]"

Purpose To assess the impact of scanner manufacturer and scan protocol on the performance of deep learning models to classify prostate cancer (PCa) aggressiveness on biparametric MRI (bpMRI). Materials and Methods In this retrospective study, 5,478 cases from ProstateNet, a PCa bpMRI dataset with examinations from 13 centers, were used to develop five deep learning (DL) models to predict PCa aggressiveness with minimal lesion information and test how using data from different subgroups-scanner manufacturers and endorectal coil (ERC) use (Siemens, Philips, GE with and without ERC and the full dataset)-impacts model performance. Performance was assessed using the area under the receiver operating characteristic curve (AUC).

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Introduction: The global prevalence of overweight and obesity has reached epidemic proportions amongst children and adolescents, with approximately one third of children in Europe being overweight or obese. There is a higher likelihood for overweight and obesity reported for vulnerable groups of children, also known as children in need. As there is currently no knowledge of the best practice interventions for improving nutrition and physical activity habits amongst these vulnerable groups, the aim of this rapid review was to examine evidence that focused on best practice interventions to tackle overweight and obesity in children in need in Greece and/or other European countries.

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Hematological parameters of the European hake () in Toroneos Gulf, northern Greece: A case study.

J Biol Methods

November 2024

Department of Ichthyology and Aquatic Environment, Faculty of Agricultural Sciences, University of Thessaly, Volos, Thessaly 38446, Greece.

Background: The European hake () is a commercially valuable demersal species widely distributed in the Mediterranean Sea. Assessing the condition of fish populations in their natural habitats is challenging due to the lack of reliable reference points.

Objective: This study aimed to utilize hematological analysis as an economical method to evaluate the physiological and health status of European hake, addressing the gap in hematological data for this species.

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Background: Although the genetic interplay with the environment has a major impact on obesity development, little is known on whether breastfeeding could modulate the genetic predisposition to obesity.

Objectives: To investigate whether breastfeeding attenuates the effect of an obesity genetic risk score (GRS) on adiposity in European adolescents.

Methods: Totally 751 adolescents from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study were included, divided according to breastfeeding status into never breastfed, 1-3 months and ≥4 months.

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Validation of the eHealth literacy scales: comparison between the shorter and longer versions.

Inform Health Soc Care

January 2025

Department of Social Informatics, Faculty of Social Sciences, University of Ljubljana, Ljubljana, Slovenia.

Digital service provision became necessary during and after the COVID-19 pandemic highlighting the technological disparity experienced by healthcare professionals and healthcare users. eHealth Literacy skills are mostly measured with the use of the eHeals, but recently more instruments have been developed to meet this need. The aim of the study was to validate and compare the two scales in Greek: the eHeals and the revised eHeals-Extended.

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Widespread screening is crucial for the early diagnosis and treatment of glaucoma, the leading cause of visual impairment and blindness. The development of portable technologies, such as smartphone-based ophthalmoscopes, able to image the optical nerve head, represents a resource for large-scale glaucoma screening. Indeed, they consist of an optical device attached to a common smartphone, making the overall device cheap and easy to use.

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During the last decades, the use of innovative hybrid materials in energy storage devices has led to notable advances in the field. However, further enhancement of their electrochemical performance faces significant challenges nowadays, imposed by the materials used in the electrodes and the electrolyte. Such problems include the high solubility of both the organic and the inorganic anode components in the electrolyte as well as the limited intrinsic electronic conductivity and substantial volume variation of the materials during cycling.

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This study investigates climate change impacts on spontaneous vegetation, focusing on the Mediterranean basin, a hotspot for climatic changes. Two case study areas, Monti Sibillini (central Italy, temperate) and Sidi Makhlouf (Southern Tunisia, arid), were selected for their contrasting climates and vegetation. Using WorldClim's CMCC-ESM2 climate model, future vegetation distribution was predicted for 2050 and 2080 under SSP 245 (optimistic) and 585 (pessimistic) scenarios.

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Preterm births constitute a major public health issue and a chronic, cross-generational condition globally. Psychological and biological factors interact in a way that women from low socio-economic status (SES) are disproportionally affected by preterm delivery and at increased risk for the development of perinatal mental health problems. Low SES constitutes one of the most evident contributors to poor neurodevelopment of preterm infants.

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Carob syrup, a traditional Mediterranean functional beverage obtained from (L.) pods, has been historically valued for its nutritional properties but is currently underutilized. This study compared the prebiotic potential of three handmade carob syrups produced by Tunisian women with commercial benchmarks from Italy, Greece and Cyprus.

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Introduction: The impact of multidisciplinary supervised cardiac rehabilitation programs on reducing the risk of having heart problems in the future is well documented. However, little is known about nurse-led post-coronary heart disease (post-CHD).

Purpose: Our aim was to evaluate the effectiveness of an educational and counseling-structured nurse-led post-CHD support program by assessing the prediction of psychological, behavioral and dietary variables in relation to adherence to a care plan in a single hospital in Athens (Greece).

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Background: Early life infections (ELIs), encompassing both viral and bacterial types, occur within the first six months of life. Influenced by genetic host factors and environmental conditions, the relationship between ELIs and subsequent allergic manifestations, particularly cow's milk protein allergy (CMPA) and atopic dermatitis (AD), is complex and not fully understood.

Objective: The aim of the current study was to examine the potential interplay between nutrition, infections, and allergic manifestations in the first six months of life in infants with a family history of allergies, who were either exclusively breastfed (EBF) or fed a combination of breast milk and standard (SF) or partially hydrolyzed infant formula (pHF).

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Redefining () species complex in Greece focusing on the mitogenome of .

Curr Res Parasitol Vector Borne Dis

November 2024

Veterinary Research Institute, Hellenic Agricultural Organization (ELGO) -DIMITRA, Campus ELGO, Thermi, 57001, Thessaloniki, Greece.

species complex, referred to as (), is distributed globally with some species distributed in specific regions and others spread globally. In Greece, () in dogs, and and in livestock, have been repeatedly reported however only based on morphological identification. Recently, there has been a great effort to accurately identify the species belonging to the species complex, using modern molecular tools and describe their spatial distribution.

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Ultrasound radiomics predict the success of US-guided percutaneous irrigation for shoulder calcific tendinopathy.

Jpn J Radiol

January 2025

Artificial Intelligence and Translational Imaging (ATI) Lab, Department of Radiology, School of Medicine, University of Crete, Voutes Campus, Heraklion, Greece.

Objective: Calcific tendinopathy, predominantly affecting rotator cuff tendons, leads to significant pain and tendon degeneration. Although US-guided percutaneous irrigation (US-PICT) is an effective treatment for this condition, prediction of patient' s response and long-term outcomes remains a challenge. This study introduces a novel radiomics-based model to forecast patient outcomes, addressing a gap in the current predictive methodologies.

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Article Synopsis
  • The paper reviews various cost containment policies aimed at controlling pharmaceutical spending by either regulating the industry or influencing consumer demand.
  • A narrative literature review highlights that governments have adopted diverse strategies like cost-sharing, value-based pricing, and the promotion of generics, but their effectiveness varies between healthcare systems and can negatively affect patients.
  • The conclusion emphasizes the need for thorough evaluation of these policies to ensure their success, as many lack strong evidence of cost-effectiveness and suggest that further research is essential to create tailored solutions that maintain affordability, fairness, and sustainability in healthcare.
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An Octopus-Inspired Soft Pneumatic Robotic Arm.

Biomimetics (Basel)

December 2024

Department of Electrical and Computer Engineering, Hellenic Mediterranean University, GR-71410 Heraklion, Greece.

Article Synopsis
  • The paper discusses a soft robot arm inspired by the octopus, focusing on its design and control methods.
  • The arm, made of soft silicone, features multiple pneumatically actuated chambers that allow for versatile bending, length adjustment, and twisting motions.
  • The design includes experimental evaluation techniques that utilize visual feedback to track the arm's shape and position in real time.
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Article Synopsis
  • BRCA1 and BRCA2 are tumor suppressor genes critical for repairing DNA damage through the Homologous Recombination pathway, and mutations in these genes are linked to higher risks of breast and ovarian cancers.
  • Methylation of BRCA1/2 promoters can create a "BRCAness" phenotype, indicating HR deficiency in tumors, even when BRCA mutations are absent, and this methylation may serve as a valuable biomarker for predicting responsiveness to therapies like PARP inhibitors.
  • The review emphasizes the need for further research into BRCA1/2 methylation as a predictive tool in cancer treatment, suggesting it could significantly enhance prognosis and treatment strategies across various cancer types.
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Unlabelled: Physical activity measured by accelerometry (PA-accelerometry) is used as an indicator of physical capacity in chronic diseases. Currently, only fragmented age ranges of reference percentile curves are available for European children and adolescents. This study aimed to provide age- and sex-specific percentiles for physical activity measured by hip-worn accelerometry derived throughout the full age range of European children and adolescents.

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Article Synopsis
  • Genome scans allow researchers to examine genetic variations linked to specific traits, but correlating individual genes with larger functional groups can be challenging.
  • This study focused on around 600,000 SNPs from European seabass populations to identify 96 candidate genes, highlighting the importance of epigenetic influences and connections to domestication-related traits.
  • The research found interactions among candidate genes, particularly in pathways related to "chromatin organization," indicating a significant role for epigenetic mechanisms in the domestication process of European seabass.
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Metal concentrations (Cu, Cr, Ni, Zn, Fe, Mn, Cd, and Pb) in marine indicator species were assessed for the study of metal pollution in the Eastern Ionian Sea during the cold period of the year (December 2018 to February 2019). Limpets and sea urchins were collected from natural populations at seven coastal stations while mussels were transplanted at three near-shore stations in the study area. Mixed mesozooplankton samples were selected from a twelve-station offshore network.

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Stress recognition identifying relevant facial action units through explainable artificial intelligence and machine learning.

Comput Methods Programs Biomed

February 2025

Translational Psychiatry, Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, Lübeck, 23562, Germany.

Article Synopsis
  • Facial expressions can reveal stress levels through specific muscle movements known as Action Units (AUs), which are analyzed using Machine Learning techniques.
  • A study created a dataset from 58 participants completing various stress-related tasks to automatically recognize facial AUs, employing advanced computational methods for feature selection and modeling stress implications.
  • Findings showed that faces exhibited more AUs and higher intensity during acute stress, achieving over 93% accuracy in distinguishing between stress and neutral conditions, highlighting the significance of certain AU combinations for stress recognition.
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  • The study emphasizes the significance of microbial communities in fish hatcheries for overall fish health and welfare, examining live feeds like microalgae and rotifers used in Mediterranean fish production.
  • Utilizing 16S rRNA amplicon Novaseq sequencing, researchers identified 46,745 taxonomically annotated ASVs and found that incoming environmental water significantly affects the presence of potential fish pathogens.
  • The analysis revealed a consistent yet diverse bacteriome across different hatcheries and highlighted specific opportunistic pathogenic genera, suggesting that mapping these communities can inform better hatchery management practices for improved fish health and sustainability.
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Article Synopsis
  • Advanced non-small-cell lung cancer (NSCLC) leads to poor prognosis and lower quality of life (QoL), with chemotherapy and immunotherapy both extending survival but causing functional impairments due to toxicity.
  • A study conducted from January 2020 to December 2021 included 111 NSCLC patients, comparing QoL and symptom burdens between 61 receiving second-line chemotherapy and 50 receiving second-line immunotherapy, using the EORTC QLQ C-30 questionnaire.
  • Results indicated moderate to good QoL in both groups, but the immunotherapy group reported significantly better QoL and functionality scores from cycles 3 to 5, while chemotherapy patients experienced more nausea, fatigue, and financial difficulties; however, immunotherapy
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Article Synopsis
  • The paper analyzes birth rate statistics in Scotland, focusing on how geopolitical concerns impact individuals' decisions to have children, especially during times of conflict or instability.
  • It employs both machine learning algorithms and classical statistical methods, incorporating the Geopolitical Risk Index to enhance birth rate predictions.
  • The results reveal that machine learning models can effectively forecast births, highlighting the significant role of geopolitical factors on birth and fertility rates in Scotland.
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Background/objectives: Complementary feeding (CF), is defined as the process of providing foods in addition to milk when breast milk or milk formula alone are no longer adequate to meet nutritional requirements. CF affects not only growth but also the subsequent development of the child's dietary preferences. The Mediterranean diet (MedDiet) is one of the most studied dietary patterns worldwide.

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