5 results match your criteria: "Hellenic Centre for Disease Control and Prevention (HCDCP)[Affiliation]"
Amino acid signatures in the HLA class II peptide-binding region associated with protection/susceptibility to the severe West Nile Virus disease.
PLoS One
April 2019
Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece.
The MHC class II region in humans is highly polymorphic. Each MHC molecule is formed by an α and a β chain, produced by different genes, creating an antigen-binding groove. In the groove there are several pockets into which antigens anchor and fit.
View Article and Find Full Text PDFHepatitis A among refugees, asylum seekers and migrants living in hosting facilities, Greece, April to December 2016.
Euro Surveill
January 2017
Hellenic Centre for Disease Control and Prevention (HCDCP), Athens, Greece.
An increased number of hepatitis A cases among refugees, asylum seekers and migrants residing in hosting facilities in Greece were recorded between April and December 2016. In total, 177 laboratory-confirmed symptomatic cases were reported; of these, 149 (84%) occurred in hosting camps mostly among Syrian children under 15 years. All cases reported symptom onset after their entry into the country.
View Article and Find Full Text PDFGenetic Contribution of MHC Class II Genes in Susceptibility to West Nile Virus Infection.
PLoS One
June 2017
Laboratory of Genetics, Comparative and Evolutionary Biology, Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece.
Article Synopsis
- West Nile Virus (WNV) is a significant global cause of viral encephalitis, with 624 reported cases in Greece over the past five years, particularly affecting immunosuppressed individuals.
- A study examining 105 WNV patients and 100 controls identified the protective gene DQA1*01:01 and the risk gene DQA1*01:02, along with associations between specific MHC class II genes and neuroinvasive disease.
- The findings suggest that MHC class II genes play a role in the immune response to WNV, providing insights into risk factors for severe cases and supporting the need for further research on genetic susceptibility to the virus.
Resistant Shigella strains in refugees, August-October 2015, Greece.
Epidemiol Infect
August 2016
National Reference Centre for Salmonella and Shigella,National School of Public Health & Central Public Health Laboratory, Hellenic Centre for Diseases Control and Prevention,Vari,Greece.
Shigellosis is endemic in most developing countries and thus a known risk in refugees and internally displaced persons. In 2015, a massive influx of refugees into Greece, due to the political crisis in the Middle East, led to the development of appropriate conditions for outbreaks of communicable diseases as shigellosis. We present a cluster of 16 shigellosis cases in refugees, detected by the implementation of a syndromic notification system in one transit centre in Athens, between 20 August and 7 October 2015.
View Article and Find Full Text PDFLaboratory and surveillance studies following a suspected Dengue case in Greece, 2012.
Int J Infect Dis
January 2015
Hellenic Centre for Disease Control and Prevention (HCDCP), Athens 15123, Greece; Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, Larissa 41222, Greece.
Objectives: To describe the laboratory assays used to investigate a suspected dengue case in summer 2012 in western Greece and to report the public health response.
Design Of Methods: Samples from the patient were tested for detection of Dengue virus (DENV) antibodies, NS1 antigen and RNA. Public health professionals interviewed residents of the village, and blood samples taken from 132 persons were tested for antibodies for DENV and West Nile virus (WNV).