6 results match your criteria: "Helios Clinics of Schwerin - University Campus of MSH Medical School Hamburg[Affiliation]"
Assessing the practice of total neoadjuvant therapy for rectal cancer: an online survey among radiation oncology departments in Germany and German-speaking regions of Austria and Switzerland.
Clin Exp Med
October 2024
Department of Radiation Oncology, Helios Clinics of Schwerin-University Campus of MSH Medical School Hamburg, Schwerin, Germany.
Total neoadjuvant therapy (TNT) of rectal cancer improves rates of pathological complete remission and progression-free survival. With improved clinical response rates, interest grew in a non-operative approach/watch and wait (WaW) for this disease. In 2020, the working groups of ACO/AIO/ARO published a consensus statement on the use of TNT, including a non-operative approach.
View Article and Find Full Text PDFCT-based radiomics for predicting breast cancer radiotherapy side effects.
Sci Rep
August 2024
Department of Radiation Oncology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, Munich, Germany.
Article Synopsis
- Skin inflammation and conditions like moist epitheliolysis and edema are common acute side effects of breast radiotherapy (RT).
- The study aimed to evaluate the effectiveness of tissue-derived radiomics features compared to total breast volume (TBV) in predicting these side effects.
- The best predictive model used a LASSO classifier based on TBV, achieving an AUROC of 0.74, similar to the AUROC of 0.75 for TBV alone, with mammary tissue showing greater predictive power than glandular tissue.
Incidental dose distribution to contralateral internal mammary nodes in breast cancer patients undergoing adjuvant radiotherapy.
Clin Transl Radiat Oncol
September 2024
Department of Radiation Oncology, TUM School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Article Synopsis
- The study investigates the lymphatic drainage to contralateral internal mammary nodes (cIMN) in breast cancer patients and highlights its neglect in current adjuvant radiotherapy practices.* -
- It analyzes the incidental radiation dose to cIMN in 120 advanced treatment plans, noting that higher doses are observed when including internal mammary node irradiation (IMNI) and during free breathing compared to deep inspiration breath hold (DIBH).* -
- The findings indicate that cIMN receives low radiation doses in existing randomized trials and treatment methods, prompting the need for further research on the effects of targeting cIMN in high-risk breast cancer patients.*
DEGRO guideline for personalized radiotherapy of brain metastases and leptomeningeal carcinomatosis in patients with breast cancer.
Strahlenther Onkol
April 2024
TUM School of Medicine, Department of Radiation Oncology, Technical University of Munich, Ismaninger Straße 22, 81675, Munich, Germany.
Article Synopsis
- The review aimed to assess the effectiveness of radiotherapy in managing brain metastases and leptomeningeal carcinomatosis in breast cancer patients and to provide treatment recommendations based on existing literature.
- A comprehensive search was conducted through PubMed for studies published between 1985 and May 2023, focusing on various types of radiotherapy for breast cancer-related brain metastases.
- Conclusions indicate that while specific radiotherapy guidelines show variability based on breast cancer subtypes, stereotactic radiosurgery is generally recommended for 1-4 brain metastases, while whole-brain radiotherapy is advised for multiple cases, especially in symptomatic patients, although treatment plans should be tailored and may include reevaluating local options after several weeks.
Cost-benefit ratio of modern medical education using micro-costing: a model calculation using the example of an innovative breast brachytherapy workshop.
Strahlenther Onkol
April 2024
Department of Radiation Oncology, University Medical Center Jena, Jena, Germany.
Article Synopsis
- Radiation oncology, particularly through multicatheter brachytherapy (MCBT), is crucial for treating early-stage breast cancer, but current training for medical residents lacks hands-on experience in this area.
- A recent study evaluated the cost-effectiveness of a hands-on brachytherapy workshop, revealing a per-participant cost of €39, which is feasible due to sponsorship of equipment.
- The workshop demonstrated significant improvements in participants' knowledge and skills, highlighting the importance of investing in such educational programs despite their resource requirements.
Staphylococcus aureus - selective reporting of antibiogram results and its impact on antibiotic use: Interventional study with a reference group on the effect of switching from non-selective to selective antibiotic reporting.
Antimicrob Resist Infect Control
November 2021
Department for Clinical Hygiene and Infectiology, Helios Clinics of Schwerin - University Campus of MSH Medical School Hamburg, Schwerin, Germany.
Background: Antimicrobial stewardship (AMS) strategies worldwide focus on optimising the use of antibiotics. Selective susceptibility reporting is recommended as an effective AMS tool although there is a lack of representative studies investigating the impact of selective susceptibility reporting on antibiotic use. The aim of this study was to investigate the impact of selective susceptibility reporting of Staphylococcus aureus (S.
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