1 results match your criteria: "Helios Clinic for Rheumatology and Clinical Immunology[Affiliation]"
Systematic Review and Metaanalysis of Pharmacological Interventions in Adult-Onset Still Disease and the Role of Biologic Disease-Modifying Antirheumatic Drugs.
J Rheumatol
May 2024
E. Feist, MD, Helios Clinic for Rheumatology and Clinical Immunology, Gommern, Germany.
Article Synopsis
- The objective of the study was to systematically review the effectiveness and safety of pharmacological treatments for adult-onset Still disease (AOSD) by analyzing data from various sources over an 11-year period.
- A total of 44 studies were examined, highlighting treatments such as NSAIDs, corticosteroids, and biologic DMARDs, with tocilizumab (TCZ), anakinra (ANK), and canakinumab (CNK) showing significant remission rates and corticosteroid (CS) discontinuation.
- While evidence supports the use of TCZ, ANK, and CNK for AOSD, findings indicate variability in treatment effectiveness and uncertainty about the comparative effectiveness of these therapies.