12 results match your criteria: "Heinrich-Heine-Universität. Tienush.Rassaf@med.uni-duesseldorf.de[Affiliation]"

Percutaneous mitral valve repair using the MitraClip system in patients with anemia.

Int J Cardiol

April 2015

University Hospital Düsseldorf, Medical Faculty, Dept. of Medicine, Division of Cardiology, Pulmonology and Vascular Medicine, Moorenstraße 5, 40225 Düsseldorf, Germany. Electronic address:

Background: Patients with anemia show a negative outcome in percutaneous coronary intervention, transcatheter aortic valve replacement and cardiac surgery. The impact of anemia on periprocedural major adverse cardiac and cerebrovascular events (MACCE) and mortality in patients undergoing treatment of severe mitral regurgitation (MR) with percutaneous mitral valve repair using the MitraClip system is not known.

Objective: To assess whether percutaneous mitral valve repair with the MitraClip system is safe and effective in patients with anemia.

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Myoglobin functions in the heart.

Free Radic Biol Med

August 2014

University Hospital Düsseldorf, Medical Faculty, Division of Cardiology, Pulmonology, and Vascular Medicine, D-40225 Düsseldorf, Germany. Electronic address:

The physiological role of myoglobin (Mb) within the heart depends on its oxygenation state. The myocardium exhibits a broad oxygen partial pressure (pO2) spectrum with a transmural gradient from the epicardial to the subendocardial layer, ranging from arterial values to an average of 19.3 mm Hg down to 0 mm Hg.

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Act fast and ventilate soft: the Düsseldorf hands-on translation of the acute respiratory distress syndrome Berlin definition.

J Crit Care

October 2014

Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty Heinrich-Heine-University, University Hospital Düsseldorf, Düsseldorf, Germany. Electronic address:

Early identification of acute respiratory distress syndrome (ARDS) and forceful implementation of standardized therapy algorithms are the mandatory basis of an effective therapy to improve patient outcome. Recently, a new definition of ARDS was implemented, which simplified the diagnostic criteria for ARDS. Evidence-based therapies are rare, but some cornerstone interventions can be recommended.

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Age-related vascular gene expression profiling in mice.

Mech Ageing Dev

January 2014

University Hospital Düsseldorf, Medical Faculty, Division of Cardiology, Pulmonology and Vascular Medicine, Moorenstraße 5, 40225 Düsseldorf, Germany. Electronic address:

Increasing age involves a number of detrimental changes in the cardiovascular system and particularly on the large arteries. It deteriorates vascular integrity and leads to increased vascular stiffness entailing hypertension with increased cardiovascular morbidity and mortality. The consequences of continuous oxidative stress and damages to biomolecules include altered gene expression, genomic instability, mutations, loss of cell division and cellular responses to increased stress.

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Dietary nitrate reverses vascular dysfunction in older adults with moderately increased cardiovascular risk.

J Am Coll Cardiol

April 2014

Department of Medicine, Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, University Hospital Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany. Electronic address:

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Myoglobin's novel role in nitrite-induced hypoxic vasodilation.

Trends Cardiovasc Med

February 2014

Medical Faculty, Department of Medicine, Division of Cardiology, Pulmonology and Vascular Medicine, University Hospital Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany. Electronic address:

Hypoxic vasodilation represents a key physiological response of the cardiovascular system to low tissue oxygen tension, adjusting local blood flow to meet the metabolic requirements in tissue. Vasodilation occurs by nitric oxide (NO) activation of the cyclic guanosine monophosphate (cGMP) signaling pathway in vascular smooth muscle cells. Under normoxia, NO is formed by the well-known endothelial NO synthase (eNOS) system while under hypoxia NO is generated from nitrite.

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Postoperative care and follow-up after coronary stenting.

Dtsch Arztebl Int

February 2013

Department of Cardiology, Pneumology and Angiology, Düsseldorf University Hospital, Heinrich-Heine-Universität.

Background: The diagnosis and treatment of coronary heart disease have improved in recent years. Most patients can return to their everyday routine a few days after a successful percutaneous coronary intervention (PCI). How should patients be followed up after the successful implantation of a coronary stent?

Method: Selective review of the pertinent literature, including current practice guidelines and recommendations.

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