53 results match your criteria: "Hefei Stomatological Hospital[Affiliation]"

Objectives: To study the clinical effect of the L-shape technique combined with concentrated growth factor on the horizontal bone defects of maxillary anterior teeth.

Methods: Twenty-five implants from 25 patients who underwent single maxillary anterior tooth implantation with simultaneous bone grafting were selected as the study subjects. Based on the bone grafting techniques, the patients were divided into a test group (L-shaped technique with guided bone regeneration combined with concentrated growth factor, 11 cases) and a control group (traditional guided bone regeneration combined with concentrated growth factor, 14 cases).

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Objective: To investigate the effects of bulk-fill, resin-based composite types (high or low viscosity) on the internal adaptation of Class V restorations.

Study Design: Experimental study. Place and Duration of the Study: Hefei Stomatological Hospital, Hefei, China, from October 2022 to December 2023.

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Purpose: To investigate the changes of root development before and after orthodontic traction of maxillary inverted impacted central incisors using CBCT and Mimics software.

Methods: Ten patients, who had a maxillary inverted impacted central incisor, were treated using a modified movable retractor combined with surgical eruption. Cone-beam computed tomography(CBCT) was taken before and after treatment.

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Di(2-ethylhexyl) phthalate (DEHP), an environmental endocrine disruptor, has hormone-like activity and endocrine-disrupting effects. However, the types of reproductive hormones associated with DEHP vary across the studies. Thus, we conducted a systematic review and meta-analysis to pool existing epidemiological evidence.

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[Effect of dual-wavelength laser combined with bioceramics iRoot SP to assist molar root canal treatment].

Shanghai Kou Qiang Yi Xue

August 2024

Hefei Stomatological Hospital, Hefei School of Stomatology, Anhui Medical University. Hefei 230001, Anhui Province, China. E-mail:

Purpose: To investigate the effect of dual-wavelength laser combined with bioceramics material iRoot SP on molar root canal treatment.

Methods: A total of 104 patients receiving root canal treatment from January 2020 to June 2023 were selected and divided into control group and experimental group according to random number table method, with 52 cases in each group. The control group was treated with iRoot SP paste, and the experimental group was treated with dual-wavelength laser(Nd:YAG and Er:YAG) combined with iRoot SP paste.

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Article Synopsis
  • The study examined the crown-root morphology and alveolar bone structure in incisors for patients with closed deep overbite, using cone-beam computed tomography (CBCT) on 40 subjects.
  • Significant differences were found between patients with Class II division 2 malocclusion and control groups in terms of crown-root ratio, angle, and alveolar bone measurements.
  • Age and gender influenced root lengths and crown-root angle in the Class II division 2 group, indicating a need for careful orthodontic management to prevent bone complications during tooth movement.
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Exposure to Multiple Metal(loid)s and Hypertension in Chinese Older Adults.

Biol Trace Elem Res

September 2024

School of Health Management, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui Province, China.

Article Synopsis
  • - The study aimed to assess the links between seven metal(loid)s (lead, manganese, nickel, arsenic, cadmium, chromium, vanadium) and hypertension in older Chinese adults, involving 1009 participants whose blood metal(loid) levels were measured.
  • - Findings showed a significant association between lead (Pb) and hypertension, with logistic regression revealing an odds ratio indicating higher hypertension risk among those with elevated Pb levels; this association remained when considering multiple metal(loid)s together.
  • - The research highlighted that the relationship between the metal(loid) mixture and hypertension could be influenced by factors like diabetes, age, BMI, and area, with Pb being the most significant metal affecting hypertension in older adults.
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Mechano-triggered eradication of dentinal tubule biofilm via in situ generation of nanoscale sonosensitizer by the tailored irrigation formulation.

Int J Pharm

November 2024

Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, School of Pharmaceutical Science & Technology, Faculty of Medicine, Tianjin University, Tianjin 300072, China. Electronic address:

Article Synopsis
  • The study addresses challenges in effectively eliminating bacteria within dentinal tubules due to poor disinfectant retention and the irritancy of traditional agents like NaClO.
  • An in situ generated sonosensitizer, made from a combination of HO, ferrocene derivative, and indocyanine green, was developed to target biofilms with fewer side effects.
  • The effectiveness of this nanosensitizer was validated through experiments demonstrating its superior antibacterial action and reduced cytotoxicity compared to conventional disinfectants.
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Over the past few decades, there have been advancements in the development of high-performance tissue adhesives as alternatives to traditional sutures and staples for rapid and effective wound closure post-surgery. While tissue adhesives offer advantages such as ease of use, short application time, and minimal tissue damage, they also face challenges related to biocompatibility, biodegradability, and adhesive strength. In this study, L-lysine diisocyanate (LDI) and trimethylolpropane (TMP) were utilized as the primary raw materials to produce a prepolymer terminated with NCO, resulting in the development of a new biocompatible polyurethane tissue adhesive (TMP-LDI).

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Concrescence is a rare dental anomaly in which two adjacent teeth are united only by their cementum. Concrescence most frequently occurs in molars, especially a third mandibular molar and a supernumerary tooth. It is rarely seen in the maxillary anterior teeth.

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This study aims to refine clinical designs within clear aligner therapy, exploring the appropriate ratio of anterior tooth retraction to intrusion under maximum anchorage. Using a three-dimensional finite element model and evaluating 19 load scenarios with first premolar extraction, the research identifies the optimal force angle for anterior tooth retraction as 45 to 55°. For clinical planning, it is recommended to design a retraction of 0.

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This study utilizes mechanochemistry to prepare retinol acetate (RA) solid dispersion (RA-sodium starch octenyl succinate (SSOS)), resulting in improved solubility, stability, and bioavailability compared with raw RA and commercial RA microcapsules. RA, poloxamer 188, SSOS, and milling beads (8 mm) were mixed in a ratio of 2:1:8:220 (w/w) and ball-milled at 100 rpm for 3 h. RA-SSOS exhibited a solubility of 1020.

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Article Synopsis
  • The study aimed to evaluate changes in upper airway dimensions and tongue position in children with mandibular retrusion and mouth breathing after using a Twin-block and maxillary expansion appliance.
  • Twenty children with Class II malocclusion were treated, and their airway volume and other measurements were analyzed using Cone-beam CT and Mimics software before and after the treatments.
  • Results showed significant increases in various airway volumes, maxillary width, and a forward movement of the tongue position, indicating improvements in airway space and overall breathability.
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Background: Numerous studies have proposed that periodontitis is a potential risk factor for Alzheimer's disease. However, the association between periodontitis and brain normal cognition in aged and elderly individuals (NCs) is unclear. Such a link could provide clues to Alzheimer's disease development and strategies for early prevention.

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Objective: To determine the clinical efficacy of ultrasonic irrigation combined with epoxy resin-based sealer in single visit root canal treatment of chronic pulpitis.

Study Design: Randomised controlled trial. Place and Duration of the Study: Department of Stomatology, Hefei BOE Hospital, Hefei, China, from March 2019 to December 2021.

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To analyze the long-term quality of life of patients with Brown Ⅱ maxillary defect repaired by tissue flap or prosthesis. Patients who underwent surgery for maxillary malignant tumors in the First Affiliated Hospital of Bengbu Medical College from 2014 to 2017 were selected to investigate the postoperative long-term (>5 years) quality of life using the fourth edition of the University of Washington quality of life questionnaire (UW-QOL). Mann Whitney test was used to examine the differences between two groups.

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The association between greenery type and gut microbiome in schizophrenia: did all greenspaces play the equivalent role?

Environ Sci Pollut Res Int

September 2023

Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, China.

In recent years, attention has been focused on the benefit of greenspace on mental health, and it is suggested this link may vary with the type of greenspace. More and more studies have emphasized the influence of the gut microbiome on schizophrenia (SCZ). However, the effects of greenspaces on the gut microbiota in SCZ and the effect of different types of greenspaces on the gut microbiota remain unclear.

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Homocysteine as a trigger and potential therapeutic target for autoimmune diseases.

Autoimmun Rev

September 2023

Teaching Center for Preventive Medicine, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, Anhui, China; Institute of Kidney Disease, Inflammation & Immunity Mediated Diseases, The Second Hospital of Anhui Medical University, China. Electronic address:

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[Clinical study of a adjustable movable retractor for maxillary labially inverted impacted central incisor].

Shanghai Kou Qiang Yi Xue

April 2023

Hefei Stomatological Hospital, Anhui Medical University, School of Stomatology. Hefei 230601, Anhui Province, China.

Purpose: To evaluate the orthodontic treatment outcome of a new adjustable movable retractor for patients with maxillary labially inverted impacted central incisors.

Methods: Ten patients, aged 7 to 10 years, who had a maxillary labially inverted impacted central incisor, were treated using a new adjustable movable retractor. Cone-beam CT(CBCT) was taken before treatment and after treatment immediately.

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Background: To achieve different central preset force levels requires various fine-tuning efforts and may elicit different uptight responses. The mandibular lever system has a distinct regularity in the fine-tuning function of the upper limbs. The purpose of the present study was to detect whether the uptight responses elicited from motivating clenching differ from those induced by motivating forearm raising at different force levels.

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Aim: The purpose of the study is to compare the labial frenectomy between the laser surgery (erbium yttrium aluminum garnet and neodymium-doped yttrium aluminum garnet (Er:YAG and Nd:YAG)) and the scalpel method.

Methods: The trial was a randomized controlled test. Thirty four patients aged from 5 to 10 years requiring the frenectomy were included in this study.

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Objective: To investigate the effect of different concentrations of platelet-rich plasma (PRP) on collagen formation via periodontal ligament fibroblasts (PDLFs) on the surface of demineralised diseased tooth roots.

Methods: Various PDLFs were grown from tissue explants, with the cells between the fifth and eighth passage in the culture used. Human whole blood obtained from healthy subjects was collected in tubes containing an anticoagulant (acid-citrate-dextrose) and centrifuged (1300 rpm for 10 min) before the supernatant PRP layer was removed.

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Article Synopsis
  • This study investigated the relationship between periodontitis (gum disease) and cognitive impairment among middle-aged and elderly individuals, comparing those with cognitive issues to healthy controls.
  • Results showed significant differences in periodontal health, with those having cognitive impairment displaying worse periodontal conditions, including more severe periodontitis and fewer remaining teeth.
  • A positive correlation was found between cognitive function and better periodontal health, suggesting that oral health may impact cognitive abilities, highlighting the need for further research on this connection.
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Article Synopsis
  • Photocross-linked alginate hydrogels show promise in bone regeneration because they are biodegradable, biocompatible, and can be designed for minimally invasive surgical applications, yet suitable degradation rates for tissue regeneration remain a challenge.* -
  • The study introduces an oxidation strategy for alginate that improves the degradation rates of the hydrogels, enhancing their physical properties and biological performances in lab tests and animal models.* -
  • Results indicate that the modified hydrogels support the activity and differentiation of bone marrow cells and have potential for clinical use in bone repair, as well as applications in tailored drug delivery systems.*
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Background: The aim of this study was to evaluate anterior teeth movement with different archwire planes and archwire sizes during space closure with and without miniscrew in sliding mechanics.

Methods: A 3D finite element method was applied to simulate anterior teeth retraction with and without miniscrew and power arm. Initial displacements and pressure stresses of periodontal tissue in anterior teeth were calculated after the teeth were applied with retraction forces with different archwire planes and archwire sizes.

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