153 results match your criteria: "Hebrew University-Hadassah School of Public Health[Affiliation]"

Article Synopsis
  • * It found that both low and high levels of PM exposure are associated with higher risks of PTB compared to moderate exposure levels, with hazard ratios indicating increased risk.
  • * Additionally, ambient temperature played a significant role, where low temperatures increased risks for PM exposure, but high temperatures showed a reversed trend, highlighting the importance of considering climate factors in understanding the risk of PTB due to PM exposure.
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Introduction: In 2018, we reported a case series of 47 patients diagnosed with cancer following several years of exposure to high-intensity whole-body radiofrequency radiation (RFR) using the parameter of percentage frequency (PF). Consistent high and statistically significant PFs of hematolymphoid (HL) cancers were found in this group and in four previous reports on RFR-exposed groups in Belgium, Poland and Israel together with increased all-cancers rates. In this paper we report a new series of 46 young cancer patients who were exposed during military service to such radiation.

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1) Compare the 5A (Ask-Advise-Assess-Assist-Arrange) practice rates between psychiatrists and primary care physicians (PCPs) regarding smoking cessation for PWSMI. 2) Compare the 5A practice rates reported by physicians with rates reported by PWSMI. 3) Identify which specialty is perceived as primarily responsible for smoking cessation promotion for PWSMI.

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While solidarity is at the basis of all social health insurance systems, little has been done to define and analyze it empirically. Equity in the delivery of medical care and progressivity of its finance are socially important, but miss the main principle of social health insurance systems - mutual help. The present study views social solidarity not as a value but as cross-subsidies among individuals, which are necessary to achieve a separation between finance and delivery of care in order to make healthcare affordable universally.

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Despite the high prevalence of smoking amongst people with serious mental illness (SMI), referral rates to smoking cessation programs (SCPs) are low. Mental health workers reticence to refer to SCPs has been attributed, in part, to their belief that quitting will have a deleterious effect on their patients' mental health status. This study's objective was to determine if participating in a smoking cessation program had an adverse effect on mental health status among people with SMI, measured here by a change in hospitalization occurrence or psychiatric medication utilization.

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Importance: Leukocyte telomere length (LTL) is a trait associated with risk of cardiovascular disease and cancer, the 2 major disease categories that largely define longevity in the United States. However, it remains unclear whether LTL is associated with the human life span.

Objective: To examine whether LTL is associated with the life span of contemporary humans.

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Changes in End-of-Life Practices in European Intensive Care Units From 1999 to 2016.

JAMA

November 2019

Department of Anesthesiology, Critical Care Medicine, and Pain Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.

Importance: End-of-life decisions occur daily in intensive care units (ICUs) around the world, and these practices could change over time.

Objective: To determine the changes in end-of-life practices in European ICUs after 16 years.

Design, Setting, And Participants: Ethicus-2 was a prospective observational study of 22 European ICUs previously included in the Ethicus-1 study (1999-2000).

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We examined the prevalence and correlates of Helicobacter pylori (H. pylori) infection according to cytotoxin-associated gene A (CagA) phenotype, a main virulence antigen, among the ethnically diverse population groups of Jerusalem. A cross-sectional study was undertaken in Arab (N = 959) and Jewish (N = 692) adults, randomly selected from Israel's national population registry in age-sex and population strata.

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Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts.

R Soc Open Sci

June 2019

Centre for Behaviour and Evolution and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

Smoking is associated with shorter leucocyte telomere length (LTL), a biomarker of increased morbidity and reduced longevity. This association is widely interpreted as evidence that smoking causes accelerated LTL attrition in adulthood, but the evidence for this is inconsistent. We analysed the association between smoking and LTL dynamics in 18 longitudinal cohorts.

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Paternal Age and Transgenerational Telomere Length Maintenance: A Simulation Model.

Sci Rep

January 2019

Center of Human Development and Aging, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, New Jersey, United States of America.

Telomere length (TL) in offspring is positively correlated with paternal age at the time of the offspring conception. The paternal-age-at-conception (PAC) effect on TL is puzzling, and its biological implication at the population level is unknown. Using a probabilistic model of transgenerational TL and population dynamics, we simulated the effect of PAC on TL in individuals over the course of 1,000 years.

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Article Synopsis
  • - Obesity may lead to shorter telomeres due to increased oxidative stress and inflammation, impacting individuals throughout their lives.
  • - A meta-analysis of 87 studies involving over 146,000 people revealed that each unit increase in BMI correlates with a significant decrease in telomere length, particularly among young adults.
  • - The findings highlighted a stronger association of BMI with telomere length in the white population, with no notable differences observed between sexes.
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Article Synopsis
  • * Findings revealed that individuals with lower cognitive scores (as measured by general intelligence tests) had significantly higher mortality risks, particularly from diabetes-related causes, even after accounting for various demographic and health factors.
  • * The research highlights the importance of cognitive function in youth as a potential predictor for serious health outcomes in later life, suggesting that addressing cognitive health may be crucial for preventing premature death from related diseases.
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Associations observed of Helicobacter pylori infection with haemoglobin levels are inconsistent. We examined associations of H. pylori sero-prevalence and serum pepsinogens (PGs), as non-invasive markers of atrophic gastritis, with haemoglobin levels.

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Article Synopsis
  • A study examined the link between body mass index (BMI) in late adolescence and the development of pancreatic cancer in adulthood, using a large cohort of Israeli Jews who underwent physical exams between 1967 and 2002.
  • Over a 23-year follow-up, researchers found that both men and women who were classified as obese (BMI ≥ 95th percentile) as adolescents had significantly higher risks of developing pancreatic cancer later in life.
  • The results indicate that not just obesity but also being overweight and having a high-normal BMI during adolescence are associated with an increased risk of pancreatic cancer, highlighting the long-term health impacts of adolescent weight status.
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Article Synopsis
  • Severe obesity among Israeli adolescents has significantly increased over the years, showing a 45-fold rise from 1967 to 2015.
  • A total of 230,639 adolescents were diagnosed with varying degrees of obesity, with about 35% of males and 43% of females with severe obesity experiencing prehypertension or hypertension.
  • Adolescents with class II and III obesity had substantially higher odds of developing high blood pressure and type 2 diabetes compared to those with overweight status, highlighting the serious health risks associated with severe obesity.
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Article Synopsis
  • Most studies on the long-term effects of adolescent BMI on health have focused on men, making this research significant for both sexes.
  • The study found that underweight women have a lower risk of cardiovascular death compared to underweight men, who are at a higher risk for non-cardiovascular death.
  • Overall, both genders show increased risks for health issues even within the high-normal BMI range, with optimal BMI values for minimal mortality differing between sexes.
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Article Synopsis
  • The study examined the link between obesity, sociodemographic factors, and the development of gastroenteropancreatic neuroendocrine tumors (GEP-NET) in a large cohort of Israeli adolescents.
  • Out of 2.3 million participants tracked from ages 16 to 19, 221 cases of GEP-NET were identified, with specific associations found between immigration from the Former Soviet Union and increased risk for certain types of tumors, as well as a connection between height and BMI with gastric tumors.
  • The results highlighted distinct risk factors for different types of GEP-NET, indicating a need for further research focused on the Former Soviet Union population and the implications of BMI and height in gastric NET cases.
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Background: Screening mammograms are widely recommended biennially for women between the ages of 50 and 74. Despite the benefits of screening mammograms, full adherence to recommendations falls below 75% in most developed countries. Many studies have identified individual (obesity, smoking, socio-economic status, and co-morbid conditions) and primary-care physician parameters (physician age, gender, clinic size and cost) that influence adherence, but little data exists from large population studies regarding the interaction of these individual factors.

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Objective: This study aimed to evaluate the association of body mass index (BMI) in adolescence with mortality attributed to kidney disease.

Methods: In this study, 2,294,139 Jewish Israeli adolescents with measured weight and height at 17 years old during the military fitness assessment were analyzed with a follow-up extending up to 45 years. All kidney-related outcomes, coded by the Central Bureau of Statistics from death notifications as the underlying cause of death, were obtained by linkage.

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Symptoms of Depression and Anxiety as Barriers to Participation in Cardiac Rehabilitation Programs Among Arab and Jewish Patients in Israel.

J Cardiopulm Rehabil Prev

May 2018

Department of Psychology, Bar-Ilan University, Ramat-Gan, Israel (Dr Vilchinsky); Hebrew University-Hadassah School of Public Health and Community Medicine, Jerusalem, Israel (Dr Reges and Dr Kark); Clalit Research Institute, Tel-Aviv, Israel (Dr Reges and Dr Leibowitz); Department of Cardiology, Meir Medical Center, Kfar-Saba, Israel (Dr Reges and Drs Khaskia and Mosseri); and New York University School of Medicine, New York, New York (Dr Leibowitz).

Purpose: Despite its proven efficacy, low participation rates in cardiac prevention and rehabilitation programs (CPRPs) prevail worldwide, especially among ethnic minorities. This is strongly evident in Israel's Arab minority. Since psychological distress has been found to be associated with CPRP participation and minorities are subjected to higher levels of distress, it is plausible that distress may be an important barrier for CPRP participation among minority patients.

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Background And Aim: We reexamine whether radio frequency radiation (RFR) in the occupational and military settings is a human carcinogen.

Methods: We extended an analysis of an already-reported case series of patients with cancer previously exposed to whole-body prolonged RFR, mainly from communication equipment and radar. We focused on hematolymphatic (HL) cancers.

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Although the management of quality of care by the health funds has contributed to its improvement, medical teams criticize the way it is performed. Many call for renewed values-driven thinking and to leave the concern for quality in the hands of the medical teams, relying on "self control and enforcement", based on values, compassion, concern for others, patient service, discipline and personal responsibility. This article aims to present an economic perspective on the measurement of quality of care.

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Short Leukocyte Telomere Length Precedes Clinical Expression of Atherosclerosis: The Blood-and-Muscle Model.

Circ Res

February 2018

From the INSERM UMRS 1116 (A.B., S.T., C.L.), Department of Geriatric Medicine, CHRU de Nancy (A.B., S.G.), Department of Vascular Surgery, CHRU de Nancy (N.S., S.M.), Department of Urology, CHRU de Nancy (J.H., P.E.), Department of Nephrology, CHRU de Nancy (L.F., M.K.), and Department of Cardiology, CHRU de Nancy (N.S.), Université de Lorraine, Nancy, France; Center of Human Development and Aging, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark (M.K., A.A.); Department of Internal Medicine, North Hospital, APHM, and UMR-S1076 (P.M.R.) and Department of Plastic Surgery, Conception Hospital, APHM and UMR-S1076 (B.B.), Aix-Marseille University, France; Department of Vascular Surgery (M.B.) and Department of Orthopedic Surgery (X.F.), North Hospital, APHM, Marseille, France; Laboratory for Experimental Surgery and Surgical Research "NS Christeas", National and Kapodistrian University of Athens, Greece (I.P.T., I.P.D., P.K., A.T., M.K., A.G., G.S.); European University of Cyprus, School of Sciences, Engomi (I.P.T.); First Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, Athens, Greece (K.P., G.S.); Department of Surgery, Hippokration Hospital and Medical School of Athens, National and Kapodistrian University of Athens, Greece (E.M.); Department of Surgery, Iaso General Hospital, Athens, Greece (M.V.-G.); Hebrew University-Hadassah School of Public Health and Community Medicine, Jerusalem, Israel (J.D.K.); and Groningen Institute for Evolutionary Life Sciences, University of Groningen, The Netherlands (S.V.).

Article Synopsis
  • Short telomere length (TL) in leukocytes is linked to atherosclerotic cardiovascular disease (ASCVD), but it's unclear whether this is due to shorter TL at birth or faster TL loss over time.
  • The study measured both leukocyte TL (LTL) and muscle TL (MTL) in individuals undergoing surgery, revealing that LTL is shorter in ASCVD patients compared to controls, and the gap between LTL and MTL increases with age for both groups.
  • Findings suggest that the accelerated loss of LTL occurs earlier in life for ASCVD patients, rather than being primarily influenced by aging itself.
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Background: Obesity was linked to altered immunity, but also to favorable outcomes among patients with infectious disease (ID) in some settings. We assessed the association between adolescent body mass index (BMI) and ID mortality.

Methods: BMI of 2 294 139 Israeli adolescents (60% men; age 17.

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