Dynamic performance of a slab track-concrete box subgrade under a double-line high speed railway.

Concrete box subgrades constructed from reinforced concrete serve as alternatives to conventional fill subgrades, effectively addressing the scarcity of high-quality fill materials. A hybrid simulation approach that merges coupled dynamics with finite element modelling was adopted for both single-line and double-line ballastless track-box subgrade systems, enabling a comparative analysis of dynamic stress, displacement, and acceleration. The results reveal that, when the two traffic conditions are compared, the dynamic response of the concrete box subgrade under double-line opposing operation shows a marked increase, particularly when the dynamic displacement increases by 80%.

The effect of taraxerol acetate extracted from dandelion on alleviating oxidative stress responses .

Oxidative stress can be alleviated by antioxidants intakes. Taraxerol acetate (TA), a natural triterpenoid extracted from dandelions, may reduce the risk of metabolic disorders by regulating oxidative stress. In the study, we investigated the effects of TA in relieving oxidative stress in murine intestinal epithelial cells using multiomics techniques.

[Distribution Characteristics and Formation Mechanism of Main Hydrochemical Ions in Qingshui River].

Qingshui River is a vital source for human life and industrial production in Zhangjiakou City. Determination of the formation mechanism of the main hydrochemical ions is important for the sustainable development and utilization of surface water resources in the Qingshui River. In view of this, 20 surface water samples were collected from the agricultural and urban reaches of the Qingshui River in July 2022.

Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults: A meta-analysis.

This study was carried out to systematically review and evaluate the influence of exercise with and without curcumin on body fat composition, glucose, and lipid metabolism in obese adults. Search for eligible studies through four databases, and then proceed with screening. The inclusion criteria are as follows: (1) obese adults; (2) randomized controlled trial (RCT); (3) classified the exercise intervention with curcumin supplementation as the exercise with curcumin (CU) group and without curcumin supplementation as the exercise without curcumin (EX) group; (4) Conducted pre- and post-training assessments, which include body fat composition, glucose and lipid metabolism parameters.

Bandgap characteristics of four component periodic pile barriers in passive vibration isolation.

Based on the local resonance theory, the vibration isolation performance of four-component periodic pile barriers consisting of a matrix, an outer pipe, an inner pipe, and a pile core was investigated using the finite element method (FEM). This configuration is contrasted with traditional three-component periodic pile barriers, which are composed of a matrix, a pipe, and a pile core. The four-component systems demonstrate significantly broader bandgaps compared to three-component systems.

Stable partial nitrification was achieved for nitrogen removal from municipal wastewater by gel immobilization: A pilot-scale study.

As an energy and carbon saving process for nitrogen removal from wastewater, the partial nitrification and denitrification process (PN/D) has been extensively researched. However, achieving stable PN in municipal wastewater has always been challenging. In this study, a gel immobilized PN/D nitrogen removal process (GI-PN/D) was established.

Optimization of Proportions of Alkali-Activated Slag-Fly Ash-Based Cemented Tailings Backfill and Its Strength Characteristics and Microstructure under Combined Action of Dry-Wet and Freeze-Thaw Cycles.

To enhance the application of alkali-activated materials in mine filling, cemented tailings backfill was prepared using slag, fly ash, sodium silicate, and NaOH as primary constituents. The effects of the raw material type and dosage on the backfill were examined through a single-factor experiment. Additionally, response surface methodology (RSM) was utilized to optimize the mixing ratios of the backfill, with a focus on fluidity and compressive strength as key objectives.

Unlocking comprehensive molecular design across all scenarios with large language model and unordered chemical language.

Molecular generation stands at the forefront of AI-driven technologies, playing a crucial role in accelerating the development of small molecule drugs. The intricate nature of practical drug discovery necessitates the development of a versatile molecular generation framework that can tackle diverse drug design challenges. However, existing methodologies often struggle to encompass all aspects of small molecule drug design, particularly those rooted in language models, especially in tasks like linker design, due to the autoregressive nature of large language model-based approaches.

Semantic differential analysis of effects of indoor soundscapes on learning efficiency during online home-based classes.

This investigation into the effects of indoor soundscapes on learning efficiency during home-based online classes amidst the COVID-19 pandemic leveraged a questionnaire survey to gather insights from participants across 32 provinces in China. The survey findings reveal a notable preference among respondents for sounds emanating from nature and culture, alongside an acceptance of sounds inherent to lectures. A significant majority showed a preference for a tranquil soundscape or one enriched with natural and cultural elements, emphasizing that such an environment, coupled with the ability for active communication, is conducive to enhancing learning efficiency.

Hydrogeochemical characteristics, driving factors, and health risk assessment of karst groundwater in Southwest Hubei Province, China.

In South China, karst groundwater is an important water resource for industrial, agricultural, and drinking purposes. However, karst aquifers are highly vulnerable to pollution, leading to deteriorating karst groundwater quality and posing potential health risks to local residents. In this study, 22 groundwater samples were collected from a karst aquifer in the southwestern part of Hubei Province.

Research on short-term power load forecasting based on VMD and GRU.

The traditional method for power load forecasting is susceptible to various factors, including holidays, seasonal variations, weather conditions, and more. These factors make it challenging to ensure the accuracy of forecasting results. Additionally, there is a limitation in extracting meaningful physical signs from power data, which ultimately reduces prediction accuracy.

Gradient failure mechanism and control technology of deep roadways under the action of deviatoric stress field.

Deformation control of deep roadways is a major challenge for mine safety production. Taking a deep roadway with a burial depth of 965 m in a mine in North China as the engineering background, on-site investigation found that significant creep deformation occurred in the surrounding rock of the roadway. The original supporting U-shaped steel support failed due to insufficient supporting strength.

The comprehensive impact of thermal-PM2.5 interaction on subjective evaluation of urban outdoor space: A pilot study in a cold region of China.

Urban outdoor space has a very important impact on the quality of people's outdoor activities, which has influenced people's health and moods. Its influence is the result of the combined action of various factors. Thermal and air quality environment are important factors affecting the overall comfort of the urban outdoor space.

Flexible wide-range multidimensional force sensors inspired by bones embedded in muscle.

Flexible sensors have been widely studied for use in motion monitoring, human‒machine interactions (HMIs), personalized medicine, and soft intelligent robots. However, their practical application is limited by their low output performance, narrow measuring range, and unidirectional force detection. Here, to achieve flexibility and high performance simultaneously, we developed a flexible wide-range multidimensional force sensor (FWMFS) similar to bones embedded in muscle structures.

Damage prediction and improvement method based on cutting mode of circular empty hole.

Based on the theory of empty hole effect of cutting blasting, the Hopkinson effect and Saint-Venant principle are integrated to establish a two-dimensional calculation model of dynamic stress evolution of the holes wall, and then the dynamic fracture mechanism and damage distribution mode of the rock mass in the cutting area under the action of longitudinal waves are predicted. The results of the calculation and numerical simulation are verified by experiments, and the results show that: The time-varying stress function of the circular cavity wall conforms to the periodic dynamic evolution of the trigonometric function, and the theoretical calculation is consistent with the simulation results. Through the calculation of the round holes cut model and the square empty hole cut model, the change of the shape of the holes in the cut area changes the failure form of the surrounding rock mass.

Coupled processes involving ammonium inputs, microbial nitrification, and calcite dissolution control riverine nitrate pollution in the piedmont zone (Qingshui River, China).

Rivers in agricultural countries widely suffer from diffuse nitrate (NO) pollution. Although pollution sources and fates of riverine NO have been reported worldwide, the driving mechanisms of riverine NO pollution associated with mineral dissolution in piedmont zones remain unclear. This study combined hydrogeochemical compositions, stable isotopes (δO-NO, δN-NO, δO-HO, and δH-HO), and molecular bioinformation to determine the pollution sources, biogeochemical evolution, and natural attenuation of riverine NO in a typical piedmont zone (Qingshui River).

Design and Implementation of a Four-Unit Array Piezoelectric Bionic MEMS Vector Hydrophone.

High-performance vector hydrophones have been gaining attention for underwater target-monitoring applications. Nevertheless, there exists the mutual constraint between sensitivity and bandwidth of a single hydrophone. To solve this problem, a four-unit array piezoelectric bionic MEMS vector hydrophone (FPVH) was developed in this paper, which has a cross-beam and a bionic fish-lateral-line-nerve-cell-cilia unit array structure.

Coupling dynamic response of saturated soil with anisotropic thermal conductivity under fractional order thermoelastic theory.

In this paper, a two-dimensional (2D) thermo-hydro-mechanical dynamic (THMD) coupling analysis in the presence of a half-space medium is studied using Ezzat's fractional order generalized theory of thermoelasticity. Using normal mode analysis (NMA), the influence of the anisotropy of the thermal conduction coefficient, fractional derivatives, and frequency on the THMD response of anisotropy, fully saturated, and poroelastic subgrade is then analyzed with a time-harmonic load including mechanical load and thermal source subjected to the surface. The general relationships among the dimensionless physical variables such as the vertical displacement, excess pore water pressure, vertical stress, and temperature distribution are graphically illustrated.

The Properties of High-Performance Concrete with Manganese Slag under Salt Action.

Manganese slag (MS) containing a certain amount of active hydration substances may be used as a kind of cementitious material. In the present study, we measured the mass, the relative dynamic modulus of elasticity (RDME), and the flexural and compressive strengths of MS high-performance concrete (MS-HPC) with added basalt fibers exposed to NaCl freeze-thaw cycles (N-FCs), NaCl dry-wet alternations (N-DAs), and NaSO dry-wet alternations (NS-DAs). Scanning electron microscope energy-dispersive spectrometer (SEM-EDS) spectra, thermogravimetric analysis (TG) curves, and X-ray diffraction spectroscopy (XRD) curves were obtained.

Effect of different exercise modalities on nonalcoholic fatty liver disease: a systematic review and network meta-analysis.

Physical exercise intervention can significantly improve the liver of patients with Non-alcoholic fatty liver disease (NAFLD), but it is unknown which exercise mode has the best effect on liver improvement in NAFLD patients. Therefore, we systematically evaluated the effect of exercise therapy on liver and blood index function of NAFLD patients through network meta-analysis (NMA). Through systematic retrieval of PubMed, Cochrane Library, Web of Science, EBSCO, and CNKI (National Knowledge Infrastructure), two reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies by means of databases from inception to January 2023.

Study of the Cold Curing Characteristics of Isocyanate-Modified Asphalt.

Isocyanate esters are widely recognized for their superior curing capabilities. Leveraging this attribute, the current research formulated a modified cold-mixed asphalt blend using 4,4'-methylene diphenyl diisocyanate (MDI). Tests and analyses of the MDI-modified asphalt with varying inclusion percentages of MDI revealed that a mixture containing 15% rock asphalt and 15% MDI-modified asphalt exhibited a more balanced, comprehensive performance.