Housing temperature influences exercise-induced glucose regulation and expression of exerkines in mice.

The impact of housing temperature on exercise-induced metabolic adaptations is not well understood, despite extensive research on the benefits of exercise for metabolic health. The aim of this study was to elucidate how housing temperatures influence the molecular responses and metabolic benefits of exercise in mice. Male C57BL/6N mice were housed at either room temperature (RT, 21°C) or in a thermoneutral environment (TN, 29°C) and subjected to either a 6-week or acute exercise regimen.

Traditional versus intensive blood glucose control: long-term target range duration and cardiovascular disease risk and all-cause mortality - a real-world cohort study.

Objective: For a long time, the dispute about whether improved glycemic control can bring significant benefits has remained unresolved. We aimed to investigate the association of time spent in different fasting glucose target ranges with cardiovascular risk and all-cause mortality in a population with type 2 diabetes (T2DM).

Method: A total of 3460 T2DM patients in the Kailuan cohort were included in this study.

A new species of Dejean (Coleoptera, Tenebrionidae) from Sichuan Province, China, with an updated key.

In this study, we describe and illustrate a new species of the genus Dejean, 1821, , which was collected in Micangshan Nature Reserve of Sichuan Province, China. Additionally, the COI mitochondrial gene was sequenced to provide additional evidence for this new species' validity. The results of phylogenetic analyses suggest that this new species is sister to Schawaller, 2008.

Enhanced Hydrogen Storage Capacity in OLi-Decorated Holey Graphitic Carbon Nitride Monolayer.

The primary challenge hindering the widespread adoption of hydrogen energy is its storage, highlighting the need for effective storage media. In this study, we utilize first-principles calculations to systematically evaluate the superalkali cluster OLi decorated on a CN monolayer for its potential as an efficient hydrogen storage material. Our findings reveal that the OLi cluster binds to each side of the CN monolayer through a charge transfer mechanism, exhibiting a binding energy of 12.

A bitter taste receptor liganded by oxalic acid inhibits brown planthopper feeding by promoting CREB phosphorylation via the PI3K-AKT signaling pathway.

Insect gustatory receptors play a critical role in modulating feeding behaviors by detecting external nutritional cues through complex biochemical pathways. Bitter taste receptors are essential for insects to identify and avoid toxins. However, the detailed molecular and cellular mechanisms by which these receptors influence insect feeding behavior remain poorly understood.

Historical inventories and future scenarios of multiple hazardous air pollutants (HAPs) emissions from the iron and steel production industry in China.

Iron and steel production (ISP) is one of significant atmospheric pollution emission sources in China. With the implementation of ultra-low emission (ULE) standards, a detailed and new updated emission inventory is urgently needed for better understanding of the temporal trends and spatial variation of emission characteristics. In this study, a unit-based comprehensive emission inventory of multiple hazardous air pollutants (HAPs) for the Chinese ISP spanned from 2012 to 2021, including the conventional pollutants, 13 kinds of Trace elements as well as 2 unconventional but toxic pollutants (PCDD/Fs, F), was dedicatedly developed by integrating dynamic localized emission factors with unit-based information of both the detailed activity level and abatement technology application.

Spatiotemporal differences induced changes in the structure and function of the gut microbiota in an endangered ungulate.

The composition and function of animal gut microbiota are shaped by various factors, among which diet is one of the major factors. Diet is affected by seasonal shifts and geographical differences, which in turn impact the host's nutritional levels. To adapt to these environmental changes, the gut microbiome often produces matching responses.

Latest advance anti-inflammatory hydrogel wound dressings and traditional used for wound healing agents.

Wound healing is a physiological process occurring after the onset of a skin lesion aiming to reconstruct the dermal barrier between the external environment and the body. Depending on the nature and duration of the healing process, wounds are classified as acute (e.g.

A comprehensive map of DNA-segment copy number variation in 491 genomes of common wheat uncovers genes associated with multiple agronomic traits.

DNA-segment copy number variations (DSCNVs), such as deletions and duplications, are important sources of genomic structural variation. However, types and sizes of DSCNVs in wheat, as well as their genome-wide distribution and potential functions are poorly known. Here, we identified 198,985 DSCNVs by investigating 491 genomes of common wheat, which accounted for 20% of the entire genome.

Developing the new diagnostic model by integrating bioinformatics and machine learning for osteoarthritis.

Background: Osteoarthritis (OA) is a common cause of disability among the elderly, profoundly affecting quality of life. This study aims to leverage bioinformatics and machine learning to develop an artificial neural network (ANN) model for diagnosing OA, providing new avenues for early diagnosis and treatment.

Methods: From the Gene Expression Omnibus (GEO) database, we first obtained OA synovial tissue microarray datasets.

Multiphase Janus Azobenzene Inverse Opal Membrane toward On-Demand Photocontrolled Motion.

Azobenzene actuators have generated extensive research investment in the field of soft robots, artificial muscles, etc., based on the typical photoresponsive - isomerization. However, it remains challenging to achieve multiphase actuation at the gas-liquid interface and liquid phase.

Recognition of Predator Type and Risk Level in Azure-Winged Magpies () Through Visual and Auditory Cues.

Predation events are an important key factor determining the survival and reproduction of prey species. To cope, prey species have evolved various anti-predator strategies, including mechanisms for accurate predator identification and distinguishing predator types and risk levels. Birds rely on visual, auditory, and olfactory cues to perceive and categorize predators.

Metal-Organic Framework-Based NF Nanotrap for the Separation of NF and CF.

As an electronic specialty gas, nitrogen trifluoride (NF) has been widely used in the semiconductor, photovoltaic, and display industries. However, NF in industrial settings is typically mixed with CF, and the distillation method commonly used for their separation consumes significant energy. Herein, we propose a novel NF nanoadsorber featuring relatively proximal unsaturated metal sites.

Iridium-Catalyzed Enantioconvergent Construction of Piperidines and Tetrahydroisoquinolines from Racemic 1,5-Diols.

We report herein a one-step synthesis of valuable enantioenriched piperidines and tetrahydroisoquinolines from readily available racemic 1,5-diols. Key to the success is the development of new iridacycle catalysts that enable efficient redox-neutral construction of two C-N bonds between diols and amines in an enantioconvergent fashion. Mechanistic studies identified an intriguing preferential oxidation of secondary versus primary alcohol in the diol substrate by the iridacycle catalyst, which set a challenging intermolecular amination of aryl-alkyl-substituted alcohol as the enantiodetermining step for this catalytic -heterocycle synthesis.

Item response theory for the color-picture version of Boston naming test in a Chinese sample with neurodegenerative diseases.

Background: Although Boston Naming Test has been thoroughly validated at a global level, there is limited assessment of item-level properties using modern psychometric methods.

Objective: This study aimed to investigate the construct validity and item-level properties of the color-picture version of Boston Naming Test (CP-BNT) in a Chinese cohort with neurodegenerative diseases.

Methods: This retrospective study included 424 participants, consisting of 118 normal controls, 152 with Alzheimer's disease, 101 with primary progressive aphasia, and 53 with other neurodegenerative diseases.

High-Yield Preparation and Characterization of Feline Albumin with Antioxidant Properties and In Vivo Safety.

To address the limited supply of serum albumin (SA) and potential pathogen contamination, focus has been concentrated on the heterologous expression of human serum albumin (HSA), particularly in . However, there are rare studies on feline serum albumin (FSA), which requires a large amount in pet foods and clinical treatment. In this work, the codon-optimized recombinant feline serum albumin (rFSA) sequence was designed and transferred into GS115 for recombinant expression.

Detection of Pear Quality Using Hyperspectral Imaging Technology and Machine Learning Analysis.

The non-destructive detection of fruit quality is indispensable in the agricultural and food industries. This study aimed to explore the application of hyperspectral imaging (HSI) technology, combined with machine learning, for a quality assessment of pears, so as to provide an efficient technical method. Six varieties of pears were used for inspection, including 'Sucui No.

Effects of Prolactin Inhibition on Lipid Metabolism in Goats.

Prolactin (PRL) has recently been found to play a role in lipid metabolism in addition to its traditional roles in lactation and reproduction. However, the effects of PRL on lipid metabolism in liver and adipose tissues are unclear. Therefore, we aimed to study the role of PRL on lipid metabolism in goats.

[Study on the regularity of acupoint selection and compatibility of acupuncture and moxibustion in the treatment of Parkinson's disease based on complex network analysis].

Objectives: To analyze the regularity of acupoint selection and compatibility of acupuncture and moxibustion for Parkinson's disease (PD) using complex network analysis technology, so as to provide the basis and treatment strategies for clinical acupuncture and moxibustion treatment of PD.

Methods: Relevant literature published in databases of China National Knowledge Infrastructure (CNKI), Wanfang, VIP, PubMed, and Web of Science from the inception to December of 2023 was retrieved. The literature was screened based on inclusion and exclusion criteria to establish a prescription database for acupuncture treatment of PD.

Pt@WS Mott-Schottky Heterojunction Boosts Light-Driven Active Ion Transport for Enhanced Ionic Power Harvesting.

Bioinspired light-driven ion transport in two-dimensional (2D) nanofluidics offers exciting prospects for solar energy harvesting. Current single-component nanofluidic membranes often suffer from low light-induced driving forces due to the easy recombination of photogenerated electron-hole pairs. Herein, we present a Pt@WS Mott-Schottky heterojunction-based 2D nanofluidic membrane for boosting light-driven active ion transport and solar enhanced ionic power harvesting.

Spatiotemporal dynamics of grassland aboveground biomass in northern China and the alpine region: Impacts of climate change and human activities.

Grassland plays a crucial role in the global cycles of matter, energy, water and, climate regulation. Biomass serves as one of the fundamental indicators for evaluating the ecological status of grassland. This study utilized the Carnegie-Ames-Stanford Approach (CASA) model to estimate Net Primary Productivity (NPP) from meteorological data and the Global Inventory Monitoring and Modeling System (GIMMS) Normalized Difference Vegetation Index (NDVI) remote sensing data for northern China's temperate and alpine grasslands from 1981 to 2015.

A new spider species of the species group (Araneae, Pholcidae) from Hebei Province, northern China.

Background: The species group currently contains 47 species. It is mainly distributed in central and southern China, as well as northern Thailand.

New Information: Yao, sp.

Brain structure and function differences across varying levels of endurance training: a cross-sectional study.

Background: Although previous studies have shown that athletes engaged in endurance sports exhibit unique characteristics of brain plasticity, there has been no systematic investigation into the structural and functional brain characteristics of endurance athletes with varying training levels.

Methods: Utilizing the "expert-novice paradigm" design, we employed functional magnetic resonance imaging (fMRI) to obtain images of brain structure and functional activity. We compared differences in gray matter volume (GMV), fractional amplitude of low-frequency fluctuations (fALFF), and degree centrality (DC) among high-level endurance athletes, moderate-level endurance athletes, and non-athlete controls.

Effects of Platycodon grandiflorum seeds exposure to static magnetic field on germination and early seedling growth.

Effects of non-uniform upward (north) and downward (south) 300 mT static magnetic field (SMF) 14 days (24 h/day) treatment of Platycodon grandiflorum seeds on germination, seedling growth, enzyme activities, malondialdehyde (MDA) level and seedling chlorophyll content were investigated under laboratory conditions. Germination rate, index and potential from magnetically exposed Anhui and Hebei Platycodon grandiflorum seeds were significantly not affected (p > 0.05), however, the values of these germination variables were notably higher in Anhui Platycodon grandiflorum seeds than Hebei seeds.

Comparative study on structure, properties, functions, and in vitro digestion characteristics of dietary fiber from Chinese chestnut prepared by different methods.

This study compared the effects of enzyme extraction (E-DF), enzyme-acid extraction (EAc-DF), enzyme-alkaline extraction (EAl-DF), ultrasonic-enzyme extraction (EU-DF), and microwave-enzyme extraction (EM-DF) on the yield, chemical composition, structural characteristics, physicochemical properties, physiological activities, and hypoglycemic activities of dietary fiber (DF) from Chinese chestnut. EAl-DF had the highest yield (25.44 ± 0.