5,509 results match your criteria: "Hebei Normal University of Science & Technology[Affiliation]"

High-performance hydrogen evolution reaction in quadratic nodal line semimetal NaCdSn.

iScience

September 2024

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130, China.

Topological nodal line semimetals (TNLSMs), which exhibit one-dimensional (1D) band crossing in their electronic band structure, have been predicted to be potential catalysts in electrocatalytic processes. However, the current studies are limited to the TNLSMs where the dispersion around the nodal line is linear in all directions. Here, the potential application of the quadratic nodal line (QNL) semimetal NaCdSn in hydrogen evolution reaction is explored.

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GO promotes detoxification of nicosulfuron in sweet corn by enhancing photosynthesis, chlorophyll fluorescence parameters, and antioxidant enzyme activity.

Sci Rep

September 2024

Tangshan Agriculture and Rural Affairs Bureau, Crop Seeds Station of Tangshan, Tangshan, 063000, Hebei Province, China.

Although graphene oxide (GO) has extensive recognized application prospects in slow-release fertilizer, plant pest control, and plant growth regulation, the incorporation of GO into nano herbicides is still in its early stages of development. This study selected a pair of sweet corn sister lines, nicosulfuron (NIF)-resistant HK301 and NIF-sensitive HK320, and sprayed them both with 80 mg kg of GO-NIF, with clean water as a control, to study the effect of GO-NIF on sweet corn seedling growth, photosynthesis, chlorophyll fluorescence, and antioxidant system enzyme activity. Compared to spraying water and GO alone, spraying GO-NIF was able to effectively reduce the toxic effect of NIF on sweet corn seedlings.

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A bird's eye view of mitochondrial unfolded protein response in cancer: mechanisms, progression and further applications.

Cell Death Dis

September 2024

Ministry of Education Key Laboratory of Molecular and Cellular Biology; Hebei Research Center of the Basic Discipline of Cell Biology, Hebei Collaborative Innovation Center for Eco-Environment, Hebei Province Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei, China.

Mitochondria are essential organelles that play critical roles in energy metabolism, apoptosis and various cellular processes. Accumulating evidence suggests that mitochondria are also involved in cancer development and progression. The mitochondrial unfolded protein response (UPR) is a complex cellular process that is activated when the protein-folding capacity of the mitochondria is overwhelmed.

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Identification of PFKFB3 as a key factor in the development of colorectal cancer and immunotherapy resistance.

Clin Exp Med

September 2024

Zhejiang Provincial Key Laboratory of Pancreatic Disease, First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.

Article Synopsis
  • Resistance to immunotherapy in colorectal cancer (CRC) is linked to the enzyme PFKFB3, which is found at higher levels in CRC tissues compared to normal ones.
  • Research shows that inhibiting PFKFB3 can reduce tumor growth and is associated with several cancer-related pathways and immune responses.
  • High expression of PFKFB3 is tied to immunotherapy resistance, particularly in patients resistant to PD-L1 blockade, highlighting its potential as a therapeutic target to improve treatment outcomes.
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Salinity stress represents a major threat to crop production by inhibiting seed germination, growth of seedlings, and final yield and, therefore, to the social and economic prosperity of developing countries. Recently, plant growth-promoting substances have been widely used as a chemical strategy for improving plant resilience towards abiotic stresses. This study aimed to determine whether melatonin (MT) and glycine betaine (GB) alone or in combination could alleviate the salinity-induced impacts on seed germination and growth of maize seedlings.

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Background: Perceived Stress has been shown as a key contributor to sleep quality, but the underlying mechanism between perceived stress and sleep quality remains unknown. This study aimed to investigate the impact of perceived stress on sleep quality of college students and the chain mediating roles of presence of meaning in life (PML) and depression, as well as the moderating role of search for meaning in life (SML).

Methods: Participants were 8178 college students (4599 boys and 3579 girls; Mage = 19.

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Dirhodium(II) complex catalyzed dehydrosilylation of styrenes: theoretical investigations on the mechanism, selectivity, and ligand effects.

Phys Chem Chem Phys

September 2024

College of Chemistry and Material Science, Hebei Key Laboratory of Inorganic and Nano-Materials, National Demonstration Center for Experimental Chemistry, Hebei Normal University, Shijiazhuang, 050024, P. R. China.

The dirhodium(II) complexes with bridging phosphine and OAc ligands showed high reactivity and selectivities in olefin dehydrosilylation. In order to determine the structure of the actual catalyst which cannot be determined experimentally, the geometries of the dirhodium catalyst, the detailed catalytic mechanism, and the stereo- and chemo-selectivities of the title reaction were studied using DFT calculations. The results showed that one OAc group is monodentate and the other is bidentate in the dirhodium catalyst C'.

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Stem cell transplantation has emerged as a promising avenue in regenerative medicine, potentially facilitating tissue repair in degenerative diseases and injuries. This review comprehensively examines recent developments and challenges in stem cell transplantation. It explores the identification and isolation of various stem cell types, including embryonic, induced pluripotent, and adult stem cells derived from multiple sources.

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Arabidopsis TIC236 contributes to proplastid development and chloroplast biogenesis during embryogenesis.

Front Plant Sci

August 2024

Hebei Research Center of the Basic Discipline of Cell Biology, Hebei Normal University, Shijiazhuang, China.

Article Synopsis
  • Plastids are important parts of plant cells that help with growth and development, and they come from a type called proplastids.
  • Scientists studied a protein called TIC236, which is needed for proplastid development, to see how it affects plant embryos.
  • Their research showed that if TIC236 doesn't work properly, it can stop the embryos from growing normally, leading to problems with cell division and proplastid development.
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Methylparaben changes the community composition, structure, and assembly processes of free-living bacteria, phytoplankton, and zooplankton.

Environ Res

December 2024

Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China; State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China; Center for Evolution and Conservation Biology, Southern Marine Sciences and Engineering Guangdong Laboratory (Guangzhou), Guangzhou, 511458, China. Electronic address:

Parabens are common contaminants in river and lake environments. However, few studies have been conducted to determine the effects of parabens on bacteria, phytoplankton, and zooplankton communities in aquatic environments. In this study, the effect of methylparaben (MP) on the diversity and community structure of the aquatic plankton microbiome was investigated by incubating a microcosm with MP at 0.

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The role of iron transporters and regulators in Alzheimer's disease and Parkinson's disease: Pathophysiological insights and therapeutic prospects.

Biomed Pharmacother

October 2024

Ministry of Education Key Laboratory of Molecular and Cellular Biology; Hebei Collaborative Innovation Center for Eco-Environment; Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology; Hebei Research Center of the Basic Discipline of Cell Biology; College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, China. Electronic address:

Brain iron homeostasis plays a vital role in maintaining brain development and controlling neuronal function under physiological conditions. Many studies have shown that the imbalance of brain iron homeostasis is closely related to the pathogenesis of neurodegenerative diseases (NDs), such as Alzheimer's disease (AD) and Parkinson's disease (PD). Recent advances have revealed the importance of iron transporters and regulatory molecules in the pathogenesis and treatment of NDs.

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Cold maceration (CM) is widely applied in winemaking to improve wine aroma and overall quality. However, more efficient CM techniques for industrial-scale winemaking are still needed. This study examined the impact of CM with indigenous cryotolerant Metschnikowia pulcherrima Mp0520 (Mp-CM) on the Muscat wine aromatic characteristics.

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Unnoticed antimicrobial resistance risk in Tibetan cities unveiled by sewage metagenomic surveillance: Compared to the eastern Chinese cities.

J Hazard Mater

November 2024

CAS Key Laboratory of Urban Pollutant Conversion, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

Sewage surveillance is a cost-effective tool for assessing antimicrobial resistance (AMR) in urban populations. However, research on sewage AMR in remote areas is still limited. Here, we used shotgun metagenomic sequencing to profile antibiotic resistance genes (ARGs) and ARG-carrying pathogens (APs) across 15 cities in Tibetan Plateau (TP) and the major cities in eastern China.

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Precise Measurement of Born Cross Sections for e^{+}e^{-}→DD[over ¯] at sqrt[s]=3.80-4.95  GeV.

Phys Rev Lett

August 2024

State Key Laboratory of Particle Detection and Electronics, Beijing 100049, Hefei 230026, People's Republic of China.

Article Synopsis
  • Data samples from the BESIII detector at the BEPCII collider were used to measure the Born cross sections for the e^{+}e^{-}→D^{0}D[over ¯]^{0} and D^{+}D^{-} processes with high precision.
  • Observations revealed clear peaks in the line shapes corresponding to various mass ranges, including G(3900), ψ(4040), ψ(4160), Y(4260), and ψ(4415).
  • These findings provide important experimental insights into the production of hadrons, particularly in the open-charm region.
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Flooding promotes the coalescence of microbial community in estuarine habitats.

Mar Environ Res

November 2024

The Fifth Geology Company of Hebei Geology & Minerals Bureau, Tangshan, Hebei, China; School of Ocean Science, China University of Geosciences, Beijing, China.

Article Synopsis
  • Microbial community coalescence occurs when microbial groups mix and integrate with their environment, influencing ecological processes, particularly in estuarine regions, which are under-researched.
  • The study examined bacterial community changes across various habitats in the Luanhe estuary during flood and normal flow periods, finding that floods reduced salinity and intensified eutrophication, thereby altering nutrient structures.
  • Flood events enhanced bacterial community mobility between different habitats, increased species overlap, and affected the stability and complexity of microbial assemblages by shifting the balance between environmental filtering and dispersal processes.
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A Green Host-Guest Protocol to Improve Water Solubility of Fluorescent Dyes.

J Phys Chem Lett

September 2024

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, Chemistry College, Beijing Normal University, Beijing 100875, P. R. China.

Improving fluorescence emission efficiency is essential to develop novel luminescent materials. However, the low water solubility of conventional fluorescent dyes is a serious obstacle to broadening the application scope. Herein, a green protocol have been proposed: Two poorly water-soluble naphthalimide derivatives MONI and MANI with high fluorescent quantum yields (larger than 0.

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Article Synopsis
  • Glioma is a very serious type of brain cancer that makes it hard for people to live well and think clearly.
  • A protein called PSMA5 is linked to how this cancer grows and was found to be really high in 28 different types of cancer compared to normal tissues.
  • Researchers want to learn about PSMA5's effects in glioma because it could help predict how patients will do and maybe even lead to new treatments.
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Full-length circRNA sequencing method using low-input RNAs and profiling of circRNAs in MPTP-PD mice on a nanopore platform.

Analyst

October 2024

State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China.

Considering the importance of accurate information of full-length (FL) transcripts in functional analysis, researchers prefer to develop new sequencing methods based on third-generation sequencing (TGS) rather than short-read sequencing. Several FL circRNA sequencing strategies have been developed. However, the current methods are inapplicable to low-biomass samples, since a large amount of total RNAs are acquired for circRNA enrichment before library preparation.

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Toxicological effects, absorption and biodegradation of bisphenols with different functional groups in Chromochloris zofingiensis.

J Hazard Mater

November 2024

Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Hebei Research Center of the Basic Discipline of Cell Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, China. Electronic address:

Bisphenols (BPs) are recognized as endocrine disrupting compounds and have garnered increasing attention due to their widespread utilization. However, the varying biological toxicities and underlying mechanisms of BPs with different functional groups remain unknown. In the present study, the toxic effects of four BPs (BPA, BPS, BPAF, and TBBPA) on a photosynthetic microalgae Chromochloris zofingiensis were compared.

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Associations of multiple serum metals with the risk of metabolic syndrome among the older population in China based on a community study: A mediation role of peripheral blood cells.

Ecotoxicol Environ Saf

October 2024

Department of Toxicology, School of Public Health, Hebei Medical University, Shijiazhuang 050017, PR China; Hebei Key Laboratory of Environment and Human Health, Shijiazhuang 050017, PR China. Electronic address:

Article Synopsis
  • A study measured serum levels of 16 metals in 852 elderly individuals in Wuhan, China, to explore their association with metabolic syndrome (MetS) and other diseases from May to July 2016.
  • Results indicated a positive correlation between certain metal mixtures and the prevalence of MetS, hypertension, and diabetes, with specific metals like zinc increasing risk and rubidium showing a protective effect.
  • Single metal effects varied; for instance, lithium and barium impacted blood pressure, while selenium affected blood glucose levels, highlighting the nuanced role of different metals in metabolic health.
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Public health emergencies influence urban carbon emissions, yet an in-depth understanding of deviations between regional emissions under such emergencies and normal levels is lacking. Inspired by the concept of resilience, we introduce the concept of regional carbon resilience and propose four resilience indicators covering periods during and after emergencies. A synthetic difference-in-differences model is employed to compute these indicators, providing a more suitable approach than traditional methods assuming unchanged levels before and after emergencies.

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Article Synopsis
  • Renal denervation (RDN) was tested in a sham-controlled trial in China to see if it can effectively lower blood pressure (BP) in hypertensive patients on medication.
  • The study involved 217 participants, showing that those who underwent RDN experienced a significantly greater reduction in 24-hour ambulatory systolic BP (by -13.0 mm Hg) compared to the placebo group (by -3.0 mm Hg).
  • Overall, RDN was found to be safe, as only one minor complication occurred, and it effectively reduced both ambulatory and office BP at the 6-month mark compared to the sham procedure.
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Purpose: The incidence of visceral leishmaniasis (VL), a global infectious disease, has been on the rise in China's Hebei province. When patients achieve clinical cure, they often do not reach an etiological cure, which may lead to recurrence of the disease. Here, we report a case of visceral leishmaniasis with a negative blood smear and bone marrow cytology.

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Late-onset Pompe disease (LOPD) is caused by a genetic deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA), leading to progressive limb-girdle weakness and respiratory impairment. The insidious onset of non-specific early symptoms often prohibits timely diagnosis. This study aimed to validate the high-risk screening criteria for LOPD in the Chinese population.

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Background: Exercise is recognized for its broad health benefits, influencing various physiological processes, including the behavior of adipose tissue macrophages (ATMs). While existing studies mainly associate ATM activity with obesity and metabolic syndrome, our study explores the impact of aerobic exercise on ATM microRNA expression profiling in a non-obese context, highlighting its general health-promoting mechanisms.

Methods: Sixty male C57BL/6 mice were randomly assigned to either a sedentary (S) or an exercise (E) group.

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