"Cu-N" Site-Driven Selectivity Switch for Electrocatalytic CO Reduction.

The comprehensive understanding of the effect of the chemical environment surrounding active sites on the pathway for the electrochemical carbon dioxide reduction reaction (eCORR) is essential for the development of advanced catalysts for large-scale applications. Based on a series of model catalysts engineered by the coordination of copper ions with various isomers of phenylenediamine [i.e.

Metal-organic frameworks encapsulating gold nanoclusters and carbon dots for ratiometric fluorescent detection of formaldehyde in real food samples, construction materials and indoor environments.

A novel fluorescence sensing nanoplatform (CDs/AuNCs@ZIF-8) encapsulating carbon dots (CDs) and gold nanoclusters (AuNCs) within a zeolitic imidazolate framework-8 (ZIF-8) was developed for ratiometric detection of formaldehyde (FA) in the medium of hydroxylamine hydrochloride (NHOH·HCl). The nanoplatform exhibited pink fluorescence due to the aggregation-induced emission (AIE) effect of AuNCs and the internal filtration effect (IFE) between AuNCs and CDs. Upon reaction between NHOH·HCl and FA, a Schiff base formed via aldehyde-diamine condensation, releasing hydrochloric acid.

Retrospective analysis of disease characteristics and treatment patterns among patients with esophageal cancer across 14 surgically represented centers.

Objective: Esophageal cancer (EC) ranks eighth among cancers in cancer-related deaths globally, and ~44% of new cases occur in China. We sought to describe the clinical characteristics and treatment landscape of EC in China before the approval of immunotherapy in 2020.

Methods: CHANNEL was a large, retrospective study using patient-level data from 14 hospitals/cancer centers across China, including adults initiating therapy for newly diagnosed EC (January to December 2018).

Density Functional Study on the Condensation and Evaporation Heats of the Nanoconfined Fluids.

Within the framework of classical density functional theory, the isosteric heat and condensation/evaporation heat of the confined methane are studied. First, the theoretical expression for condensation/evaporation heat is derived on the basis of the first law of thermodynamics. The method for computation is also proposed.

Lattice plainification and band engineering lead to high thermoelectric cooling and power generation in n-type BiTe with mass production.

Thermoelectrics can mutually convert between thermal and electrical energy, ensuring its utilization in both power generation and solid-state cooling. BiTe exhibits promising room-temperature performance, making it the sole commercially available thermoelectrics to date. Guided by the lattice plainification strategy, we introduce trace amounts of Cu into n-type Bi(Te, Se) (BTS) to occupy Bi vacancies, thereby simultaneously weakening defect scattering and modulating the electronic bands.

Improved performances toward electrochemical carbon dioxide and oxygen reductions by iron-doped stannum nanoparticles.

The CO reduction reaction (CORR) and oxygen reduction reaction (ORR) show great promise for expanding the use of renewable energy sources and fostering carbon neutrality. Sn-based catalysts show CORR activity; however, they have been rarely reported in the ORR. Herein, we prepared a nitrogen-carbon structure loaded with Fe-doped Sn nanoparticles (Fe-Sn/NC), which has good ORR and CORR activity.

Enhancing open-circuit voltage in FAPbI perovskite solar cells self-formation of coherent buried interface FAPbICl.

The interfaces between the perovskite and charge-transporting layers typically exhibit high defect concentrations, which are the primary cause of open-circuit voltage loss. Passivating the interface between the perovskite and electron-transporting layer is particularly challenging due to the dissolution of surface treatment agents during the perovskite coating. In this study, a coherent FAPbICl buried interface was simultaneously formed during the preparation of FAPbI.

ICE1 (Inducer of CBF Expression 1) Is Essential for the Jasmonate-Regulated Development of Stamen in Arabidopsis thaliana.

Floral organ development, pollen germination and pollen tube growth are crucial for plant sexual reproduction. Phytohormones maintain these processes by regulating the expression and activity of various transcription factors. ICE1, a MYC-like bHLH transcription factor, has been revealed to be involved in cold acclimatisation of Arabidopsis.

Program temperature-controlled drying: An effective way to improve the quality of hot-air dried shiitake mushrooms.

This study applied program temperature-controlled drying (PTCD) to optimize the hot-air drying process for shiitake mushrooms, adjusting the drying temperature based on activity changes of γ-glutamyl transpeptidase (γ-GTase) and cysteine sulfoxide lyase (C-S lyase). Compared with constant temperature drying, PTCD (ST_75 and ST_150) significantly enhanced the umami and aroma profiles and sulfur compounds, increasing the levels of key flavor compounds such as glutamic acid and 5'-GMP. Moreover, PTCD improved rehydration capacity (515.

Spatiotemporal evolution of landscape ecological risk and its driving factors of the Beijing-Tianjin-Hebei major mineral belt, 1985-2022.

The Beijing-Tianjin-Hebei major mineral belt represents a significant economic development area in China. Effective monitoring and assessment of the regional landscape ecological risk can provide a scientific basis for an ecological protection strategy for the environmental protection of the Beijing-Tianjin-Hebei major mineral belt. In this study, a landscape ecological risk index was constructed based on land use/land cover, and the spatial and temporal variations of landscape ecological risk were subsequently analyzed.

Establishment and validation of HPLC methods for the determination of folic acid and parabens antimicrobial agents on folic acid oral solution.

Background: As the common antibacterial drugs in folic acid oral liquid, parabens are listed as mandatory substances in the quality standard. Both the Chinese Pharmacopoeia and the United States Pharmacopoeia use high performance liquid chromatography for the determination of folic acid, but the quantitative methods of parabens are different. Pharmacopoeias use different instruments to quantify folic acid and parabens, resulting in cumbersome and cumbersome detection methods.

Anti-obesity and gut microbiota modulation effects of chondroitin sulfate on obese mice induced by high-fat diet.

Despite the extensive application of chondroitin sulfate (CS), a type of biological macromolecule, in various fields, including biomedicine, cosmetics, food, and pharmaceuticals, research into its potential anti-obesity properties remains limited. In this study, the impacts of CS on obese mice induced by a high-fat diet (HFD) were investigated. The results showed that supplementing CS effectively controlled body weight gain and fat accumulation (perirenal fat and epididymal fat) compared to the control group of obese mice.

An insight into the mechanisms of foxtail millet bran polysaccharides retarding the digestibility of millet starch by in vitro simulated digestion.

The influence of foxtail millet bran polysaccharides (MPs) on millet starch (MS) digestion was investigated in the three aspects (MPs, MP-MS gel properties, the interactions between MPs and MS). The results showed that MPs with a higher Mw (58-2552 kDa), a narrower Mw distribution (1.85-9.

Spatial-temporal correlation effects and persistent synergistic control benefits of fine particulate matter and carbon emissions in China.

The synergistic reduction of air pollutants and carbon dioxide (CO) emissions is a key component in achieving China's strategy of pollution and carbon reduction. This study quantitatively evaluates the spatiotemporal linkages between PM and CO emissions, as well as the benefits of sustained synergistic control, across over 360 Chinese cities from 2005 to 2020. We employed spatiotemporal analysis, coupled coordinateness modeling, the Hurst index, and generalized linear mixed modeling (GLMM).

Zinc Combined with Metformin Corrects Zinc Homeostasis and Improves Steroid Synthesis and Semen Quality in Male Type 2 Diabetic Mice by Activating PI3K/AKT/mTOR Pathway.

Male infertility is a common complication of diabetes. Diabetes leads to the decrease of zinc (Zn) content, which is a necessary trace element to maintain the normal structure and function of reproductive organs and spermatogenesis. The purpose of this study was to investigate the effect of metformin combined with zinc on testis and sperm in diabetic mice.

Pro-Arg, The Potential Anti-Diabetes Peptide, Screened from Almond by In-Silico Analysis.

Insulin resistance was considered to be the most important clinical phenotype of type 2 diabetes (T2DM). Almond is a widely-consumed nut and long-term intake was beneficial to alleviating insulin resistance in patients with T2DM. Hence, screening of anti-diabetic peptides from almond proteins was feasible based on the effectiveness of peptides in the treatment of T2DM.

Mitigating bias in AI mortality predictions for minority populations: a transfer learning approach.

Background: The COVID-19 pandemic has highlighted the crucial role of artificial intelligence (AI) in predicting mortality and guiding healthcare decisions. However, AI models may perpetuate or exacerbate existing health disparities due to demographic biases, particularly affecting racial and ethnic minorities. The objective of this study is to investigate the demographic biases in AI models predicting COVID-19 mortality and to assess the effectiveness of transfer learning in improving model fairness across diverse demographic groups.

Influence of drought stress on phosphorus dynamics and maize growth in tropical ecosystems.

Drought has a significant impact on ecosystem functions, especially on the biogeochemical cycling of phosphorus (P), which is a crucial nutrient for plant growth and productivity. Despite its importance, the effects of different drought scenarios on soil P cycling and availability remain poorly understood in previous studies. This study simulated drought conditions in tropical soils using maize as a test crop under varying field capacity (FC) levels (100%, 80%, 60%, 40%, and 20%) over a 60-day pot experiment.

Climate change influences on the potential geographic distribution of the invasive Asian longhorned tick, Haemaphysalis longicornis.

The Asian long-horned tick, Haemaphysalis longicornis Neumann, 1901, is the competent vector for severe fever with thrombocytopenia syndrome virus (SFTSV). Haemaphysalis longicornis originated mainly in eastern Asia and invaded many areas like Australia, New Zealand, and the Pacific islands, and was recently introduced to eastern parts of the USA. This species is characterized by high adaptability to a wide range of temperatures and can reproduce parthenogenically under stressful conditions.

Hemocyanin contributes to embryonic adaptation to hypoxia in the migratory locust.

Ambient hypoxia can pose a major threat to the survival of metazoan organisms, especially insect embryos. Hemocyanin exhibits dominant expression in insect embryos, but its specific roles in hypoxia adaptation remain unexplored. Soil-dwelling locust eggs may frequently experience hypoxia during development.

Preventive vs. Therapeutic Effects of Shoutai Wan: Maintaining an Acidic Microenvironment at the Maternal-Fetal Interface to Promote Angiogenesis and Minimize Pregnancy Loss in RSA Mice.

Ethnopharmacological Relevance: The classic TCM prescription, Shoutai Wan (STW), is extensively used in clinical settings to manage threatened miscarriage and Recurrent spontaneous abortion (RSA). The complexity of pregnancy physiology, coupled with diverse etiologies, and the specificity of energy metabolism for normal embryo attachment and development,pose challenges to clinical diagnosis and treatment. The specific molecular mechanisms of how STW regulates these biological processes and contributes to the treatment of RSA remain to be elucidated.

Impact of low-carbon economic policies on the corporate environmental responsibility model in China.

This study investigates the impact of low-carbon economic policies on Corporate Environmental Responsibility (CER) in Chinese A-share listed companies, with a particular focus on the role of financing constraints as a mediating factor. Despite a decrease in environmental pollution incidents in 2022, the economic and social impacts of such incidents remain significant, highlighting the need for stronger environmental governance. Building upon previous research, this study utilizes data from the Shanghai and Shenzhen stock exchanges (2010-2020) and employs a Difference-in-Differences (DID) model to assess the effects of low-carbon economic policies introduced in 2016 on CER.

Neural Stem/Progenitor Cell Therapy in Patients and Animals with Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-analysis.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative malady that causes progressive degeneration and loss of motor neuron function in the brain and spinal cord, eventually resulting in muscular atrophy, paralysis, and death. Neural stem/progenitor cell (NSPC) transplantation can improve bodily function in animals and delay disease progression in patients with ALS. This paper summarizes and analyzes the efficacy and safety of neural stem/progenitor cell (NSPC) transplantation as a treatment for ALS, aiming to improve function and delay disease progression in patients.

Dipolar wavevector interference induces a polar skyrmion lattice in strained BiFeO films.

Skyrmions can form regular arrangements, so-called skyrmion crystals (SkXs). A mode with multiple wavevectors q then describes the arrangement. While magnetic SkXs, which can emerge in the presence of Dzyaloshinskii-Moriya interaction, are well established, polar skyrmion lattices are still elusive.