8 results match your criteria: "Heart Center at University of Leipzig and Leipzig Heart Institute[Affiliation]"
Right Ventricular Dysfunction in Patients Undergoing High-Risk PCI with Impella.
J Card Fail
October 2024
Clinical Trials Center, Cardiovascular Research Foundation, New York, New York, USA.
Article Synopsis
- * Among 239 patients assessed, 124 had RVD, which was linked to factors like lower left ventricular ejection fraction and higher blood urea nitrogen levels, but did not significantly affect certain immediate procedural outcomes.
- * RVD was found to be a strong predictor of worse long-term outcomes, with higher rates of major adverse cardiac and cerebrovascular events (MACCE) at 90 days and increased mortality at one year post-procedure.
Mitral regurgitation evolution after transcatheter tricuspid valve interventions-a sub-analysis of the TriValve registry.
Eur Heart J Cardiovasc Imaging
December 2024
HerzZentrum Hirslanden, Hirslanden Clinic, Zurich, Switzerland.
Article Synopsis
- Doctors are studying how a procedure called transcatheter tricuspid valve interventions (TTVI) affects patients with heart issues, specifically focusing on something called mitral regurgitation (MR) after the procedure.
- They looked at data from a big group of patients and found that many showed improvement in MR after the procedure, but some got worse.
- They discovered that certain factors, like successful procedures and specific treatments, could help predict whether a patient’s MR would improve or get worse after TTVI.
Congestion patterns in severe tricuspid regurgitation and transcatheter treatment: Insights from a multicentre registry.
Eur J Heart Fail
April 2024
Department of Cardiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Article Synopsis
- * In a multicenter registry of 813 patients, findings showed that right atrial pressure (RAP) is a significant predictor of mortality, with a notable portion of patients classified into different congestion categories before the intervention.
- * The results indicate that patients experiencing right-sided or bilateral congestion had lower procedural success rates and shorter survival times, highlighting the importance of understanding congestion patterns for better patient management and therapeutic approaches.
Radiation to Illuminate the Path of Neuromodulation for Pulmonary Hypertension.
JACC Basic Transl Sci
February 2024
Department of Cardiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Interatrial Shunt Devices.
Heart Fail Clin
January 2024
Division of Cardiology, Department of Medicine, Duke University, Durham, NC, USA; Duke Clinical Research Institute, Durham, NC, USA. Electronic address:
Elevated left atrial pressure during exercise is a hallmark of heart failure (HF) and is associated with adverse left atrial remodeling and poor outcomes. To decompress the pressure-overloaded left atrium in patients with HF, several device-based approaches have been developed to create a permanent, pressure-dependent, left-to-right interatrial shunt. Such approaches are currently in various stages of investigations in both HF with reduced ejection fraction (EF) and HF with preserved EF.
View Article and Find Full Text PDFModulation of Pulsatile Left Ventricular Afterload by Renal Denervation in Heart Failure With Preserved Ejection Fraction.
Circ Heart Fail
October 2023
Department of Cardiology, Heart Center at University of Leipzig and Leipzig Heart Institute, Germany (K.-P.R., K.-P.K., S.R., A.R.S., M.v.R., H.T., K.F., P.L.).
Background: Arterial stiffening contributes to hemodynamic derangements in heart failure with preserved ejection fraction (HFpEF). We sought to investigate the impact of renal denervation on pulsatile left ventricular loading in patients with HFpEF and hypertensive patients without heart failure (control).
Methods: Patients underwent renal denervation for treatment of hypertension and were followed up at 3 months at a single center.
Stressed Blood Volume in Severe Tricuspid Regurgitation: Implications for Transcatheter Treatment.
JACC Cardiovasc Interv
September 2023
Department of Cardiology, Heart Center at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
Article Synopsis
- Tricuspid transcatheter edge-to-edge repair (TEER) can help patients with tricuspid regurgitation (TR), but many still face risks post-procedure, especially related to stressed blood volume (eSBV).
- A study of 279 patients found that eSBV is linked to factors like obesity and organ dysfunction, critically impacting heart failure and blood flow dynamics.
- Higher eSBV was associated with worse outcomes, such as persistent venous congestion after TEER and increased rates of death and hospitalizations for heart failure, suggesting the need for better patient screening for additional treatments.
Catheter ablation of atrial flutter: Critical isthmus identification and localization.
Rev Port Cardiol (Engl Ed)
June 2020
Department of Electrophysiology, Leipzig Heart Center at University of Leipzig and Leipzig Heart Institute (LHI), Leipzig, Germany. Electronic address: