3,944 results match your criteria: "Healthcare Center[Affiliation]"
Front Pharmacol
September 2024
Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, United States.
Introduction: In collaboration with the Minnesota Hmong community, we have previously discovered significant differences in allele frequencies for key Single Nucleotide Variations (SNVs) within Very Important Pharmacogenes (VIPs) between Hmong and East Asians. Recognizing the potential clinical implications of these observed differences, we sought to validate these observations in a Hmong cohort residing in California, the state with the largest Hmong population in the US. Robust validation of these differences would affect motivation for clinicians treating individuals who identify as Hmong to consider pharmacogenomic (PGx) testing as a means to improve clinical decision making when using therapeutic agents in this unique population.
View Article and Find Full Text PDFTransl Psychiatry
October 2024
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Atherosclerosis
November 2024
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea. Electronic address:
Digit Health
October 2024
Participatory eHealth and Health Data Research Group, Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Am J Psychiatry
December 2024
Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Pathak, Wendt, Polimanti); Veterans Affairs Connecticut Healthcare Center, West Haven, Conn. (Pathak, Polimanti); Department of Anthropology, University of Toronto, Toronto, Ont. (Wendt); Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ont. (Wendt); University of California San Diego, Department of Psychiatry, La Jolla, Calif. (Maihofer, Stein, Nievergelt); Veterans Affairs San Diego Healthcare System, Center of Excellence for Stress and Mental Health, San Diego (Maihofer, Stein, Nievergelt); Veterans Affairs San Diego Healthcare System, Research Service, San Diego (Maihofer, Nievergelt); Veterans Affairs San Diego Healthcare System, Psychiatry Service, San Diego (Stein); Harvard Medical School, Department of Psychiatry, Boston; McLean Hospital, Belmont, Mass. (Ressler); Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston (Koenen); Wu Tsai Institute, Yale University, New Haven (Polimanti).
Biosci Microbiota Food Health
August 2024
Global Innovation Center, Nissin Foods Holdings Co., Ltd., 2100 Tobukimachi, Hachioji-shi, Tokyo 192-0001, Japan.
This research aimed to examine the effect of daily intake of food containing strain T21 (T21) on skin conditions and inflammation-related markers in healthy adults who experience itching because of dry skin and have an atopic predisposition. A randomized, double-blind, placebo-controlled parallel-group study was conducted on 44 subjects aged 20 to 64 years. Subjects were randomly assigned to receive a T21-containing food or placebo daily for 8 weeks.
View Article and Find Full Text PDFAnn Med Surg (Lond)
October 2024
Department of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.
Sci Bull (Beijing)
November 2024
Department of Neurology and China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing 100053, China; Beijing Institute of Brain Disorders, Capital Medical University, Beijing 100053, China. Electronic address:
Brain diseases, mainly including acute brain injuries, neurodegenerative diseases, and mental disorders, have posed a significant threat to human health worldwide. Due to the limited regenerative capability and the existence of the blood-brain barrier, the brain was previously thought to be separated from the rest of the body. Currently, various cross-talks between the central nervous system and peripheral organs have been widely described, including the brain-gut axis, the brain-liver axis, the brain-skeletal muscle axis, and the brain-bone axis.
View Article and Find Full Text PDFBMC Nurs
October 2024
Nursing and Health Care Research Unit (Investén-isciii), Biomedical Research Network Center in Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
Background: The Otago Exercise Programme is an effective intervention for falls prevention. However, there is limited evidence in relation to studies that compare efficacy for falls prevention when delivered Otago Exercise Programme in a group or individual format in a primary care context.
Objective: To compare the Otago Exercise Programme delivered as a group vs.
J Theor Biol
December 2024
Physics and Applied Mathematics Unit, Indian Statistical Institute, 203, B.T. Road, Kolkata, 700108, India. Electronic address:
Species frequently engage in both competitive and cooperative interactions, delicately balancing these dynamics to optimize their chances of survival and reproduction. While competition drives individuals to compete for limited resources, cooperation can emerge as a strategic response, mitigating risk and enhancing collective payoff. To bridge theoretical game approaches such as payoff, cooperation, and defections in ecological systems, we propose a two-species predator-prey model inspired by the principles and variations of the prisoner's dilemma game.
View Article and Find Full Text PDFJ Cardiovasc Med (Hagerstown)
November 2024
Department of Family Medicine.
Background: Cardiovascular risk assessment is a critical component of healthcare, guiding preventive and therapeutic strategies. In this study, we developed and evaluated an image-based electrocardiogram (ECG) analyzing an artificial intelligence (AI) model that estimates biological age and mortality risk.
Methods: Using a dataset of 978 319 ECGs from 250 145 patients at Seoul National University Bundang Hospital, we developed a deep-learning model utilizing printed 12-lead ECG images to estimate patients' age (ECG-Age) and 1- and 5-year mortality risks.
Biomaterials
March 2025
Wearable Intelligent Systems and Healthcare Center (WISH Center), Institute for Matter and Systems, Georgia Institute of Technology, Atlanta, GA, 30332, USA; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University School of Medicine, Atlanta, GA, 30332, USA; Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA. Electronic address:
The widespread emergence of airborne diseases has transformed our lifestyle, and respirators have become an essential part of daily life. Nevertheless, finding respirators that fit well can be challenging due to the variety of human facial sizes and shapes, potentially compromising protection. In addition, the current respirators do not inform the user of the air quality in case of continuous long-term use.
View Article and Find Full Text PDFSci Rep
September 2024
Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Carbohydrate antigen 19-9 (CA19-9) levels are associated with glycemic control, insulin resistance, and chronic complications in patients with type 2 diabetes (T2D). Women generally show higher CA19-9 levels despite a greater T2D prevalence in men. We evaluated the sex-specific longitudinal associations between CA19-9 levels and T2D incidence.
View Article and Find Full Text PDFRheumatology (Oxford)
September 2024
Department of Biomedical Sciences, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.
Objectives: Certain studies propose that antibiotic use may influence rheumatoid arthritis (RA) incidence, but the clear association between antibiotics and RA remains unclear. Therefore, this study aimed to examine the relationship between antibiotics and RA risk to provide additional epidemiological evidence.
Methods: This population-based retrospective cohort study was conducted with adults aged 40 years or older using the Korean National Health Insurance Service (NHIS) database.
Healthcare (Basel)
September 2024
Department of Family Medicine & Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Objectives: Estimating the risk of diabetes mellitus (DM) is important for the proper management of patients with spinal cord injury (SCI). We investigated the short-term and long-term risks of DM among patients with SCI, according to the presence or severity of post-SCI disability and the level of injury.
Methods: We conducted a retrospective cohort study using the Korean National Health Insurance Service (2010-2018) database.
BMC Public Health
September 2024
Department of Physical Education, Seoul National University, Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.
Background: Physical activity has been shown to correlate with mental health and a reduction in symptoms of depression. However, the majority of research has focused only on the effects of either aerobic or nonaerobic exercise on depressive symptoms, while the use of novel technological innovations such as mobile phone-based activity programs and their effects on movement characteristics are underrepresented. This study had two objectives: (1) to investigate how effectively 4 weeks of mobile phone-based physical activity can affect depressive scores (CES-10-D and PHQ) and fitness levels and (2) to investigate the whether 4 weeks of mobile phone-based physical activity affected participants' movement characteristics.
View Article and Find Full Text PDFPLOS Digit Health
September 2024
Department of Emergency Medicine, Weill Cornell Medicine, New York, New York, United States of America.
Return visit admissions (RVA), which are instances where patients discharged from the emergency department (ED) rapidly return and require hospital admission, have been associated with quality issues and adverse outcomes. We developed and validated a machine learning model to predict 72-hour RVA using electronic health records (EHR) data. Study data were extracted from EHR data in 2019 from three urban EDs.
View Article and Find Full Text PDFJ Clin Gastroenterol
September 2024
Department of Gastroenterology, Center for Advanced Therapeutic Endoscopy, Centura Health, Denver, CO.
Inquiry
September 2024
Department of Geriatrics, Arkansas Geriatric Education Collaborative-Reynolds Institute on Aging, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
This study explores the implementation of the Age-Friendly Health Systems (AFHS) 4Ms Framework into primary care clinics in rural Arkansas, facilitated by the AGEC and funded by The Health Resources and Services Administration's Geriatric Workforce Enhancement Program (GWEP) grant. Implementation success is evaluated by monitoring merit-based incentive payment system (MIPS) measures and other variables, providing insight into the effectiveness of integrating AFHS and enhancing older adult care. AGEC employed implementation strategies (train-the-trainer, audit and feedback, and clinical reminders using Electronic Medical Record (EMR)), the i-PARIHS implementation framework, and the RE-AIM evaluation framework to facilitate integration of the AFHS 4Ms Framework into partnered rural federally qualified healthcare clinics (FQHC).
View Article and Find Full Text PDFFront Pharmacol
September 2024
Department of Traditional Chinese Medicine, the Second Medical Center & National Clinical Research Center of Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Purpose: Wuwei Kushen Changrong capsule (Composite Colon-soluble Capsule, CSCC) is a Chinese patent medicine developed to treat ulcerative colitis. Studies highlight CSCC potential efficacy for ulcerative colitis (UC) but unclear mechanism limits its widely treatment for patients. We aimed to investigate the anti-colitis efficacy of CSCC and explore the mechanism by which GPR43 inhibits the NLRP3/STAT3 signaling pathway, thereby mediating the protective effects of CSCC on the intestinal barrier.
View Article and Find Full Text PDFInt J Spine Surg
September 2024
Division of Orthopedic Surgery, Jerry L Pettis Memorial Veterans Hospital, Loma Linda, CA, USA
Background: This study aimed to determine whether the iliac crests are truly at the level of L4 to L5, accounting for patient demographic and anthropometric characteristics.
Methods: We measured the umbilicus and iliac crests relative to the lumbar spine using computed tomography of patients without spinal pathology, accounting for the influences of patient height, weight, body mass index (BMI), sex, race, and ethnicity.
Results: A total of 834 patients (391 men and 443 women) were reviewed.
Clin Kidney J
September 2024
Department of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
Background: Creatinine-based equations are the most used to estimate glomerular filtration rate (eGFR). The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), the re-expressed Lund-Malmö Revised (r-LMR) and the European Kidney Function Consortium (EKFC) equations are the most validated. The EKFC and r-LMR equations have been suggested to have better performances in young adults, but this is debated.
View Article and Find Full Text PDFEur Arch Psychiatry Clin Neurosci
September 2024
Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Heroin dependence (HD) is a complex disease with a substantial genetic contribution and is associated with traits of impulsivity and specific personality traits. The neurotrophic factor nerve growth factor (NGF) may mediate the reward processes in HD. This study aims to investigate whether NGF gene polymorphisms are associated with the co-occurrence of HD and impulsivity/specific personality traits in HD patients.
View Article and Find Full Text PDFEur J Dent
September 2024
Primary Healthcare Center, Ministry of Health, Riyadh, Saudi Arabia.
Objectives: The identification of key genes associated with amelogenesis would be helpful in finding solutions to genetic disorders in oral biology. The study aimed to use analysis to identify the key genes involved in tooth development associated with preameloblasts (PABs) and secretory ameloblasts (SABs).
Material And Methods: The data was subjected to quality analysis and uniform manifold approximation and projection analysis.