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Diffusion-Restricted Lesions of the Splenium: Clinical Presentation, Radiographic Patterns, and Patient Outcomes.
Neurol Clin Pract
October 2023
University of Michigan (B. Stamm, CML), Ann Arbor; Northwestern University (B. Stamm, MT, DTJ, FS), Chicago, IL; Neurology (B. Sabayan), HealthPartners Institute (EC), Minneapolis, MN.
Background And Objectives: Diffusion-restricted (DR) lesions of the splenium are encountered in a wide variety of pathologies, and their significance is often unclear. We sought to report the spectrum of clinical presentations, neuroimaging patterns, and the predictors of radiographic and clinical outcomes from DR splenial lesions.
Methods: This was a single-center, retrospective cohort study from January 1, 2009, to August 1, 2020.