Effect of earplug/eye mask on sleep and delirium in intensive care patients.

Background: Environmental factors such as loud sounds and bright lights in intensive care units can cause sleep disorders and delirium.

Aim: The present study aims to investigate the effects of the overnight use of earplugs and eye masks by intensive care patients on their sleep quality and the degree of delirium.

Study Design: This randomized controlled experimental study was conducted on the patients admitted to a coronary intensive care unit.

Nurses' Attitudes Towards Death and Its Relationship With Anxiety Levels.

This study examined nurses' attitudes towards death, anxiety levels, and socio-demographic characteristics affecting their attitudes towards death. Three hundred and eighty-four nurses participated in the study. A questionnaire form, the Death Attitude Profile-Revised (DAP-R), and the Penn State Worry Questionnaire were applied to the nurses.

Comparison of serum BDNF, IL-1β, IL-6, TNF-α, CRP and leucocyte levels in unipolar mania and bipolar disorder.

Objective: Unipolar mania is not included in the diagnostic and statistical manual of mental disorders-5 (DSM-5) as a separate diagnosis, although it is defined by widely accepted diagnostic criteria. The aim of this study was to investigate the differences between unipolar mania and bipolar disorder in terms of clinical and inflammatory parameters.

Methods: The data of 495 hospitalised patients with bipolar disorder diagnoses were analysed retrospectively.

Examination of factors affecting oral health in patients receiving haemodialysis.

Background: Patients receiving haemodialysis suffer from oral problems, pain, deteriorated nutrition, and decreased self-confidence and quality of life. Nurses have a critical role in the evaluation and care of oral health.

Objectives: The aim was to investigate the associations between socio-demographic characteristics, medication use, and biochemical blood levels and oral health in adult patients receiving haemodialysis treatment.

Assessment of the genotoxic potential of tetrachlorvinphos insecticide by cytokinesis-block micronucleus and sister chromatid exchange assays.

Tetrachlorvinphos is an organophosphate that is classified as a carcinogen in humans by several authorities. Due to very limited data regarding the genotoxic potential, we aimed to comprehensively investigate in vitro genotoxic potential of tetrachlorvinphos. We performed our study by applying the cytokinesis-block micronucleus cytome and sister chromatid exchange (SCE) assays to human peripheral blood lymphocytes.

Evaluation of DNA damages in congenital hearing loss patients.

In the current study, we aimed to compare the level of genetic damages measured as micronucleus (MN), nucleoplasmic bridge (NPB), and nuclear bud formation (NBUD) in congenital hearing loss patients (n = 17) and control group (n = 24). The cytokinesis-blocked micronucleus assay (CBMN) was applied to the blood samples to measure the frequency of the markers in both groups. The frequencies of MN of hearing loss patients were found to be consistently significantly higher than those obtained for the control group (p < 0.

The Meaning and Role of Spirituality for Older Adults: A Qualitative Study.

This study is designed to identify the meaning and effects perceived by a person concerning religion and spirituality as that person grows old. A total of nineteen adults aged 65-88, five of whom were male and fourteen of whom were female, participated in semistructured interviews. As per the results of the thematic analysis, four main themes emerged: the meaning of spirituality, spiritual practices, the effect of spirituality and the meaning of growing old for the person.

The Effect of Spirituality on the Subjective Recovery of Psychiatric Patients.

Spiritual well-being is among the factors that affect subjective recovery. This study aimed to explore the relationship between subjective recovery and spiritual well-being among psychiatric patients and to identify the factors that affected their subjective recovery. A descriptive, cross-sectional study was conducted with 96 patients admitted to the psychiatry clinic of a hospital.

Chemical characterization, cytotoxic, antioxidant, antimicrobial, and enzyme inhibitory effects of different extracts from one sage ( L.) from Turkey: open a new window on industrial purposes.

In the present study, the methanolic, hydro-methanolic, dichloromethane, hexane and aqueous extracts of L. (Family: Lamiaceae), a lemon-scented herb, were tested for total phenolic (TPC) and flavonoid content (TFC) and antioxidant activities were evaluated using a battery of assays (2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), ferric reducing antioxidant power (FRAP), cupric reducing antioxidant capacity, total antioxidant capacity (TAC) (phosphomolybdenum) and metal chelating). Enzyme inhibitory effects were investigated using acetyl- (AChE), butyryl-cholinesterase (BChE), tyrosinase, α-amylase and α-glucosidase as target enzymes.

Psychologic distress and sleep quality among adults in Turkey during the COVID-19 pandemic.

Objective: The sudden novel coronavirus disease 2019 (COVID-19) pandemic has created a negative effect on the mental health of the public. In this study, in relation to the pandemic, psychological distress, sleep quality and affecting factors in adults were examined.

Methods: Using the convenience sampling method, the Pittsburgh Sleep Quality Index and questionnaires to determine psychological distress levels and sociodemographic characteristics were distributed online to 405 participants.

sp. nov., isolated from soil.

A novel actinomycete, designated strain HC44, was isolated from a soil sample collected from Hacibektaş, Turkey, and characterized using a polyphasic approach. The strain had morphological characteristics and chemotaxonomic properties identical to those of members of the genus . Phylogenetic analyses based on 16S rRNA gene sequence comparisons revealed that HC44 clustered with members of the genus and the highest 16S rRNA gene sequence similarity values were obtained with NBRC 13094 (97.

Network analysis, chemical characterization, antioxidant and enzyme inhibitory effects of foxglove (Digitalis cariensis Boiss. ex Jaub. & Spach): A novel raw material for pharmaceutical applications.

The present study outlines the phenolic composition and pharmacological properties of different extracts of Digitalis cariensis Boiss. ex Jaub. & Spach root and aerial parts.

Metabolomics profiling and biological properties of root extracts from two Asphodelus species: A. albus and A. aestivus.

The pharmacological properties of Asphodelus species have been advocated previously. In this respect, the present study attempts to unravel the antioxidant and enzyme inhibitory activity of root extracts of two Asphodelus species, namely, A. albus and A.

Different working conditions shift the genetic damage levels of pesticide-exposed agriculture workers.

In the current study, we had two main purposes. Firstly, we aimed to compare genetic damages in the agricultural workers of two different types of environmental conditions including the greenhouse and open fields. Secondly, we aimed to compare genetic damages in the total agricultural workers as the exposed group (greenhouse and open field workers) (n = 114) and the non-exposed control group (n = 98) living in the same area in Canakkale, Turkey.

Phytocomplex Characterization and Biological Evaluation of Powdered Fruits and Leaves from .

Fully ripe fruits and mature leaves of were harvested and analyzed by means of analytical and biological tests to better comprehend the chemical composition and therapeutic/nutraceutical potential of this plant. Fruits and leaves were dried and the obtained powders were analyzed to study their color character and (via headspace gas chromatography) describe the chemical profile. Subsequently, they were submitted to a chloroform-methanol extraction, to a hydroalcoholic extraction procedure assisted or not by microwaves, and to an extraction with supercritical CO, assisted or not by ethanol as the co-solvent, to detect the polyphenolic and the volatile content.

Assessment of the genotoxic potential of a migraine-specific drug by comet and cytokinesis-block micronucleus assays.

: Eletriptan is a migraine-specific drug-containing the triptan group. In terms of drug safety, the present study aimed to investigate the genotoxic potential of eletriptan.: We conducted our study by using the cytokinesis-block micronucleus cytome (CBMN) assay, a comprehensive method for measuring micronucleus formation, and a sensitive method for detecting DNA-strand breaks.

Nonomuraea basaltis sp. nov., a siderophore-producing actinobacteria isolated from surface soil of basaltic parent material.

A Gram-stain-positive, aerobic, spore-forming actinobacterial strain, designated 160415, was isolated from a surface soil sample, which was formed on basaltic parent material, collected from Samsun, Turkey. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain 160415 clustered closely with species of the genus Nonomuraea, and showed the highest sequence similarity to Nonomuraea zeae NEAU-ND5, Nonomuraea candida HMC10 and Nonomuraea turkmeniaca DSM 43926 with 99.1%, 98.

Investigation of the efficacy of daidzein in experimental knee osteoarthritis-induced with monosodium iodoacetate in rats.

Background: Osteoarthritis (OA) is a degenerative chronic illness that most frequently occurs in the knee joint. Daidzein (DZ) an isoflavone has anti-inflammatory and antioxidant activity. The aim of this study was to evaluate the effectiveness of DZ as a treatment for experimental knee OA (KOA) in rats.

Association Between Spiritual Well-Being and Resilience Among Turkish Hemodialysis Patients.

This study aimed to determine the association between spiritual well-being and resilience among Turkish hemodialysis patients. This cross-sectional study was conducted with 134 hemodialysis patients treated at two state hospitals' hemodialysis units between February 2019 and July 2019. The data were collected with a Personal Information Form, the Spiritual Well-Being Scale and the Resilience Scale for Adults with the face-to-face interview technique.

Determination of depression, anxiety and stress (DAS) levels in patients with atopic dermatitis: a case-control study.

The present study was aimed at comparing depression, anxiety and stress (DAS) levels of individuals with atopic dermatitis with those of the individuals without atopic dermatitis, and to examine the DAS levels of the patients with atopic dermatitis in terms of their socio-demographic characteristics. Case control study conducted in a city in western Turkey. The present study in which the relational screening model was used was conducted with patients with atopic dermatitis who presented to the Dermatology Clinic/Polyclinic of a university hospital and healthy subjects, and volunteered to participate in the study.

In-vitro and in-silico anticancer potential of taxoids from Taxus wallichiana Zucc.

Introduction: Natural products derived from medicinal plants provide beneficial cancer chemotherapeutic drugs. Bioactive constituents from plants are explored for their anticancer properties.

Methods: Three known compounds (deacetylbaccatin III, tasumatrol B, and taxawallin J) were isolated from Taxus wallichiana.

Results of buccal micronucleus cytome assay in pesticide-exposed and non-exposed group.

Since many different pesticides have been used occupationally, there have been inconsistent results regarding DNA damages among greenhouse workers. Thus, the aim of the study is to evaluate DNA damages, cell death, and chromosomal instability by using the buccal micronucleus cytome (BMcyt) assay in greenhouse workers and to compare those with a non-exposed group. The BMcyt assay was applied to the exfoliated buccal cell samples collected from 66 pesticide-exposed and 50 non-exposed individuals.

Comet assay for assessment of DNA damage in greenhouse workers exposed to pesticides.

The main goal of the present study was to determine DNA damage in pesticide-exposed greenhouse workers and pesticides non-exposed controls. The DNA damage was measured by alkaline comet assay method (pH>13) in 41 greenhouse workers and 45 non-exposed individuals as the control. Pesticide exposure was assessed by duration of working in the greenhouse and pesticide application in the greenhouse time.