291 results match your criteria: "Health Science Institute of Eskişehir Osmangazi University[Affiliation]"

The Satisfaction With Life Scale (SWLS) is a widely used self-report measure of subjective well-being, but studies of its measurement invariance across a large number of nations remain limited. Here, we utilised the Body Image in Nature (BINS) dataset-with data collected between 2020 and 2022 -to assess measurement invariance of the SWLS across 65 nations, 40 languages, gender identities, and age groups (N = 56,968). All participants completed the SWLS under largely uniform conditions.

View Article and Find Full Text PDF

Comparison of Coconut and Sunflower Seed Oils in Improving the Skin Integrity and Weight Gain of Infants in the Neonatal ICU.

Adv Skin Wound Care

January 2025

Öznur Tiryaki, PhD, RN, is Associate Professor, Faculty of Health Sciences, Department of Midwifery, Sakarya University, Sakarya, Turkey. Hamide Zengin, PhD, RN, is Associate Professor, Faculty of Health Science, Department of Pediatric Nursing, Eskişehir Osmangazi University, Eskişehir, Turkey. Also at Sakarya University, Nursan Çınar, PhD, RN, is Professor, Faculty of Health Sciences, Department of Pediatric Nursing; Meltem Karabay, MD, is Associate Professor, Faculty of Medicine, Research and Training Hospital of Sakarya, Division of Neonatology, Department of Pediatrics; İbrahim Caner, MD, is Professor, Faculty of Medicine, Research and Training Hospital of Sakarya, Division of Neonatology, Department of Pediatrics; and Ertuğrul Güçlü, MD, is Professor, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology.

Objective: To determine the effects of sunflower seed oil and coconut oil on the skin integrity and weight gain of preterm infants in the neonatal ICU.

Methods: In this randomized controlled trial, 66 preterm neonates (34-37 weeks' gestation) in the neonatal ICU of a training and research hospital were equally divided into three groups: sunflower seed oil, coconut oil, and control. The weights of neonates in all three groups were measured at admission to the neonatal ICU, at discharge, and at 1 month postdischarge.

View Article and Find Full Text PDF

The prognostic value of the neutrophil-lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates the relationship between admission NLR, stroke severity and 90-day outcomes in patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. A retrospective multicenter study was conducted with 1082 patients treated with mechanical thrombectomy for acute ischemic stroke.

View Article and Find Full Text PDF

Testing the Dispersal-Origin-Status-Impact (DOSI) scheme to prioritise non-native and translocated species management.

Sci Rep

December 2024

Global Ecology | Partuyarta Ngadluku Wardli Kuu, College of Science and Engineering, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia.

Assessing actual and potential impacts of non-native species is necessary for prioritising their management. Traditional assessments often occur at the species level, potentially overlooking differences among populations. The recently developed Dispersal-Origin-Status-Impact (DOSI) assessment scheme addresses this by treating biological invasions as population-level phenomena, incorporating the complexities affecting populations of non-native species.

View Article and Find Full Text PDF

Sex differences in clinical and polysomnographic features of obstructive sleep apnea: The Turkish sleep apnea database (TURKAPNE) cohort.

Sleep Med

December 2024

Department of Pulmonary Medicine, Koc University School of Medicine, Istanbul, Türkiye; Koc University Research Center for Translational Medicine (KUTTAM), Istanbul, Türkiye; Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden; Department of Clinical Sciences, Respiratory Medicine and Allergology, Lund University School of Medicine, Lund, Sweden; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

Background: Previous reports from relatively small clinical cohorts have suggested that the clinical presentation of obstructive sleep apnea (OSA) differs between men and women.

Objective: We aimed to explore sex differences in clinical and polysomnographic features of OSA in a large nationwide registry.

Methods: Participants from the ongoing Turkish Sleep Apnea Database (TURKAPNE) Study from 34 centers were included in the current analysis.

View Article and Find Full Text PDF

Community-acquired respiratory viral infections (CARV) significantly impact patients with hematological malignancies (HM), leading to high morbidity and mortality. However, large-scale, real-world data on CARV in these patients is limited. This study analyzed data from the EPICOVIDEHA-EPIFLUEHA registry, focusing on patients with HM diagnosed with CARV during the 2023-2024 autumn-winter season.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates a new meningococcal vaccine (MenABCWY) that combines components of the existing MenB vaccine (4CMenB) and the MenACWY vaccine, aiming to provide broad immunization against various meningococcal strains and ease vaccination schedules.
  • Conducted as a phase 3 randomized trial across multiple countries, healthy participants aged 10-25 were assigned to receive different vaccine schedules to assess safety, immune response, and consistency of vaccine lots.
  • The trial primarily focused on the immune response to MenB strains, comparing MenABCWY's effectiveness to 4CMenB and evaluating the consistency of immune responses among different production lots of the vaccines.
View Article and Find Full Text PDF
Article Synopsis
  • Meningococcal serogroup B (MenB) vaccination with the 4CMenB vaccine was tested for its effectiveness and safety among 3,651 healthy participants aged 10 to 25, using different dosing schedules (0-2, 0-6, and 0-2-6 months).
  • The study measured the immune response through two methods: a test-based approach showing high immune breadth (over 78%) and a responder-based approach indicating a significant percentage of participants achieved strong responses (up to 93.4% for the 0-2-6 schedule).
  • The results showed no major differences in effectiveness across the dosing schedules, confirming that the simpler 2-dose regimen (0-2)
View Article and Find Full Text PDF

Background: The study aimed to translate the Profile of Fatigue and Discomfort-Sicca Symptoms Inventory Short Form questionnaire into the Turkish language (PROFAD-SSI-SF-T) and to investigate its psychometric properties.

Methods: The study was completed by 104 patients with primary Sjögren's syndrome (pSS), and 83 patients filled out the scale a second time after 7 days for the retest measurement. The PROFAD-SSISF-T, Functional Assessment Chronic Illness Therapy (Fatigue) (FACIT-F), EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI), European Quality of Life 5 Dimensions (EQ-5D), and Patient Global Assessment (PaGA) were applied to 104 patients with pSS for convergent validity.

View Article and Find Full Text PDF

Clinical Perspectives and Novel Preclinical Models of Malignant Pleural Mesothelioma: A Critical Review.

ACS Pharmacol Transl Sci

November 2024

Eskisehir Osmangazi University, Faculty of Medicine, Department of Pulmonary Diseases, Lung and Pleural Cancers Research and Clinical Center, Eskisehir 26040, Turkey.

Pleural mesothelioma (PM), a rare malignant tumor explicitly associated with asbestos and erionite exposures, has become a global health problem due to limited treatment options and a poor prognosis, in which the median life expectancy varies depending on the method of treatment. However, the importance of early diagnosis is emphasized, and the practical methods have not matured yet. This study provides a critical overview of PM, addressing various aspects like epidemiology, etiology, diagnosis, treatment options, and the potential use of advanced technologies like microfluidic chip-based models for research and diagnosis.

View Article and Find Full Text PDF

Introduction: Hearing aid (HA) manufacturers have introduced behind-the-ear (BTE) models where the microphone is positioned in the ear canal, which could impact auditory performance by distorting the pinna's acoustic cues. This study aimed to compare two different BTE HAs with varying microphone positions: the receiver in the ear (RITE) and the transducer in the ear (TIE).

Methods: The study involved 10 participants who had never used HAs before.

View Article and Find Full Text PDF

Zinc oxide nanomaterials: Safeguarding food quality and sustainability.

Compr Rev Food Sci Food Saf

November 2024

Department of Food Engineering, Faculty of Engineering, Ege University, Izmir, Bornova, Turkey.

In this era, where food safety and sustainability are paramount concerns, the utilization of zinc oxide (ZnO) nanoparticles (NPs) is a promising solution to enhance the safety, quality, and sustainability of food products. ZnO NPs in the food industry have evolved significantly over time, reflecting advancements in synthesizing methods, antimicrobial activities, and risk assessment considerations for human health and the environment. This comprehensive review delves into the historical trajectory, current applications, and prospects of ZnO NPs in food-related contexts.

View Article and Find Full Text PDF

Background: The one-minute sit-to-stand test (1STST) is an easy-to-administer, space and time-saving test for determining functional exercise capacity in cardiac disease. This study aimed to investigate the 1STST -test-retest reliability and convergent validity and compare its physiological responses to the six-minute walk test (6MWT) in patients with Atrial fibrillation (AF).

Methods: Forty-five patients with AF were included in this study.

View Article and Find Full Text PDF

Aim: To determine the experiences of nurses and midwives providing perinatal care in an earthquake area.

Background: On February 6, 2023, two earthquakes measuring 7.8 and 7.

View Article and Find Full Text PDF
Article Synopsis
  • Many Western European countries have strong surveillance and reporting systems for invasive meningococcal disease (IMD), primarily caused by serogroup B (MenB), and they implement standardized testing and vaccination programs.
  • Despite these efforts, there is still a significant need for advocacy to improve diagnosis, testing, and treatment of meningococcal disease.
  • Recent awareness campaigns have highlighted the dangers of antibiotic resistance, with some countries reporting strains of meningococcus that are resistant to key antibiotics.
View Article and Find Full Text PDF

Although metallic implants provide most of the required properties for bone-related applications, especially orthopedic implants, insufficient osseointegration, which may lead to loosening of the implant or prolonged healing time, is still an issue to be resolved. Osseointegration can be improved via application of various surface treatments on the metal surface. The current study focuses on a novel surface microdeformation method, which enables the formation of controlled surface patterns of various parameters.

View Article and Find Full Text PDF

Common viral respiratory infections in children with cancer during the COVID-19 pandemic: a multicenter study from Türkiye.

Turk J Pediatr

October 2024

Department of Pediatric Hematology Oncology, Yıldırım Beyazıt University Faculty of Medicine, Ankara Bilkent City Hospital, Ankara, Türkiye.

Article Synopsis
  • During the COVID-19 pandemic lockdown, the study assessed respiratory viral infections in children with cancer, highlighting their clinical impact.
  • Of the 265 episodes evaluated, human rhinovirus/enterovirus was the most common pathogen identified, with significant complications noted, including a higher rate of lower respiratory tract infections.
  • The findings emphasize the necessity for quicker detection and treatment of respiratory viruses to prevent severe outcomes in this vulnerable population.
View Article and Find Full Text PDF

Convenient rapid prototyping microphysiological niche for mimicking liver native basement membrane: Liver sinusoid on a chip.

Colloids Surf B Biointerfaces

January 2025

Cellular Therapy and Stem Cell Production Application and Research Center (ESTEM), Eskisehir Osmangazi University, Eskisehir, Türkiye; Department of Stem Cell, Institute of Health Sciences, Eskisehir Osmangazi University, Eskisehir, Türkiye; Department of Metallurgical and Materials Engineering, Eskisehir Osmangazi University, Eskisehir, Türkiye; Translational Medicine Research and Clinical Center (TATUM), Eskisehir Osmangazi University, Eskisehir, Türkiye. Electronic address:

Liver is responsible for the metabolization processes of up to 90 % of compounds and toxins in the body. Therefore liver-on-a-chip systems, as an in vitro promising cell culture platform, have great importance for fundamental science and drug development. In most of the liver-on-a-chip studies, seeding cells on both sides of a porous membrane, which represents the basement membrane, fail to resemble the native characteristics of biochemical, biophysical, and mechanical properties.

View Article and Find Full Text PDF

Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study.

ESC Heart Fail

September 2024

Department of Cardiology, İzmir University of Economics, Faculty of Medicine, Medical Point Hospital, İzmir, Türkiye.

Aims: We aimed to determine the use of sodium-glucose cotransporter 2 inhibitors (SGLT2is) and to identify clinical factors associated with their use in patients with heart failure (HF) in a real-life setting.

Methods: Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study is a multicentre, cross-sectional and observational study that included HF patients in the outpatient setting regardless of ejection fraction from 19 cardiology centres between August 2023 and December 2023.

Results: The study population consisted of 1923 patients with HF, predominantly men (61.

View Article and Find Full Text PDF

Objective: This study was designed to examine the mediator role of resilience in the relationship between chronotype and mental toughness in adolescents.

Methods: The descriptive correlational study was completed with 342 high school students from one school in Türkiye (mean age 17.25±1.

View Article and Find Full Text PDF

Aims: We analysed baseline characteristics and guideline-directed medical therapy (GDMT) use and decisions in the European Society of Cardiology (ESC) Heart Failure (HF) III Registry.

Methods And Results: Between 1 November 2018 and 31 December 2020, 10 162 patients with acute HF (AHF, 39%, age 70 [62-79], 36% women) or outpatient visit for HF (61%, age 66 [58-75], 33% women), with HF with reduced (HFrEF, 57%), mildly reduced (HFmrEF, 17%) or preserved (HFpEF, 26%) ejection fraction were enrolled from 220 centres in 41 European or ESC-affiliated countries. With AHF, 97% were hospitalized, 2.

View Article and Find Full Text PDF
Article Synopsis
  • - The study assessed trauma CT interpretation proficiency among emergency medicine residents in Turkey, finding a median accuracy rate of 64.9% with factors influencing interpretation performance analyzed.
  • - Four main factors linked to interpretation failure were identified: shorter interpretation times, lower self-confidence, over-reliance on radiology reports, and lack of departmental training programs.
  • - The findings suggest the necessity for improved educational strategies in radiology for emergency medicine residents to enhance their skills in trauma CT interpretation and ultimately improve patient care outcomes.
View Article and Find Full Text PDF

Web of venom: exploration of big data resources in animal toxin research.

Gigascience

January 2024

CIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Porto, Portugal.

Article Synopsis
  • - Research on animal venoms involves various fields like biology, pharmacology, and bioinformatics, yet accessing the necessary tools and data can be difficult for nonexperts due to their scattered availability online.
  • - The article identifies and discusses key web resources and databases for venom research, compiling them into a comprehensive table found on the VenomZone website to aid scientists in their work.
  • - It also addresses the current challenges in the field, advocating for better standards, data sharing, and community collaboration to enhance the accessibility and effectiveness of venom research.
View Article and Find Full Text PDF

Genome-wide discovery of selection signatures in four Anatolian sheep breeds revealed by ddRADseq.

Sci Rep

September 2024

Department of Medical Services and Techniques, Vocational School of Burdur Health Services, Burdur Mehmet Akif Ersoy University, Burdur, 15100, Türkiye.

High-density genomic data analyzed by accurate statistical methods are of potential to enlighten past breeding practices such as selection by unraveling fixed regions. In this study, four native Turkish sheep breeds (80 samples) were genotyped via 296.097 single nucleotide polymorphisms (SNPs) detected by double-digest restriction site-associated DNA (ddRADseq) library preparation combined with the Illumina HiSeq X Ten instrument in order to identify genes under selection pressure.

View Article and Find Full Text PDF