31 results match your criteria: "Health Research Institute Biodonostia[Affiliation]"
Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival.
J Natl Cancer Inst
December 2014
International Agency for Research on Cancer, Lyon, France (MJ, AF, DCM, PB); Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia (JKB, GG, GiS); Bevital AS, Bergen, Norway (ØM); Norwegian Institute of Public Health and Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (SEV); Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK (RCT); Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute (ISPO), Florence, Italy (DP); Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy (AM); Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy (SS); Hellenic Health Foundation, Athens, Greece (AT, DT); World Health Organization Collaborating Center for Food and Nutrition Policies, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece (AT, PL); Department of Epidemiology, Harvard School of Public Health, Boston, MA (PL, DT); Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece (PL, DT); Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden (BL); Department of Biobank Research, Umeå University, Umeå, Sweden (GH); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway (EW, GuS); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Catalan Institute of Oncology (ICO), Barcelona, Spain (CAG); Public Health Direction, Basque regional Health Department, San Sebastian, Spain (MD); Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP) - Health Research Institute (BIODONOSTIA), Spain (HBBdM, MMR); Department of Epidemiology, Julius Center for Health
Background: The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.
Methods: The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants with blood samples between 1992 and 2000, and this analysis included 556 RCC case-control pairs.
Intrauterine and early postnatal exposure to outdoor air pollution and lung function at preschool age.
Thorax
January 2015
Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain Hospital del Mar Medical Research Institute (IMIM), Barcelona, Catalonia, Spain Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
Background: Effects of prenatal and postnatal exposure to air pollution on lung function at preschool age remain unexplored. We examined the association of exposure to air pollution during specific trimesters of pregnancy and postnatal life with lung function in preschoolers.
Methods: Lung function was assessed with spirometry in preschoolers aged 4.
Deficit of vitamin D in pregnancy and growth and overweight in the offspring.
Int J Obes (Lond)
January 2015
1] Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain [2] Hospital del Mar Medical Research Institute (IMIM), Barcelona, Catalonia, Spain [3] Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain [4] CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Background: Maternal vitamin D status during fetal development may influence offspring growth and risk of obesity; however, evidence in humans is limited.
Objective: To investigate whether maternal circulating 25-hydroxyvitamin D3 (25(OH)D3) concentration in pregnancy is associated with offspring prenatal and postnatal growth and overweight.
Methods: Plasma 25(OH)D3 concentration was measured in pregnant women (median weeks of gestation 14.
Association between different obesity measures and the risk of stroke in the EPIC Spanish cohort.
Eur J Nutr
April 2015
Neuroscience Department, Health Research Institute Biodonostia, Po Doctor Begiristain, San Sebastian, 20014, Spain,
Introduction: There is still a scientific debate on the exact role played by obesity on stroke risk.
Objective: The aim of the study was to analyze the association between obesity, measured by different indices such as body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR) and a new one called A Body Shape Index (ABSI) and the risk of total and ischemic stroke.
Subjects/methods: A total of 41,020 subjects (15,490 men and 25,530 women) aged 29-69 years participated in the study.
Factors associated with second-hand smoke exposure in non-smoking pregnant women in Spain: self-reported exposure and urinary cotinine levels.
Sci Total Environ
February 2014
Public Health Department, Basque Government, San Sebastian, Spain; Health Research Institute (BIODONOSTIA), San Sebastian, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Spain. Electronic address:
The aim of this study was to evaluate the main sources of and sociodemographic factors associated with second-hand smoke (SHS) exposure, assessed both by questionnaire and by urinary cotinine (UC) levels, in non-smoking pregnant women. We conducted a cross-sectional study in pregnant women from 4 different regions in Spain. A total of 1783 non-smoking pregnant women completed a questionnaire about their previous smoking habit and SHS exposure in their 3rd trimester of pregnancy and provided a urine sample for measuring UC levels.
View Article and Find Full Text PDFIn vitro correction of a pseudoexon-generating deep intronic mutation in LGMD2A by antisense oligonucleotides and modified small nuclear RNAs.
Hum Mutat
October 2013
Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; Neuroscience Area, Health Research Institute Biodonostia, San Sebastian, Spain.
Limb-girdle muscular dystrophy type 2A (LGMD2A) is the most frequent autosomal recessive muscular dystrophy. It is caused by mutations in the calpain-3 (CAPN3) gene. The majority of the mutations described to date are located in the coding sequence of the gene.
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