2 results match your criteria: "Health Department of Alicante-General Hospital[Affiliation]"
Bone fractures in patients using tapentadol or oxycodone: an exploratory US claims database study.
Pain Manag
January 2021
Department of Medical Sciences & Public Health, University of Cagliari, Azienda Ospedaliera Universitaria of Cagliari, Cagliari, Italy.
To explore fracture outcomes with tapentadol or oxycodone, two opioids with differing mechanisms of action. Retrospective cohort pilot study, using MarketScan Commercial and Medicare Supplemental claims databases, on patients with postoperative pain, back pain, or osteoarthritis and ≥1 claim for tapentadol (n = 16,457), oxycodone (n = 1,356,920), or both (n = 15,893) between June 2009 and December 2015. During 266,826 and 9,007,889 days of tapentadol and oxycodone treatment, patients evidenced 1080 and 72,275 fractures, respectively.
View Article and Find Full Text PDFOPRM1 Gene Interaction with Sleep in Chronic Pain Patients Treated with Opioids.
Pain Physician
January 2019
Pain Unit, Health Department of Alicante-General Hospital, Alicante, Spain; Neuropharmacology on Pain (NED), Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain; Clinical Pharmacology Unit, Health Department of Alicante-General Hospital, Alicante, Spain.
Background: The experience of chronic non-cancer pain (CNCP) is one of the most common reasons individuals seek medical attention. Patients with CNCP frequently experience concomitant sleep-related problems.
Objectives: The aim was to evaluate sleep problems in opioid naïve CNCP patients, before and after opioid titration, analyzing the influence of OPRM1 gene variants.