Translation and Validation of Rating-of-Fatigue Scale to be Used in Nonsurgical Endodontic Re-treatment.

Background: This study aimed to translate and validate the rating-of-fatigue (ROF) scale in the Kannada language.

Methods: This current study involved two steps, where forward translation, backward translation, cross-cultural adaptation, and test of a pre-final version of the ROF scale were conducted in the first step. Content validity, face validity, and construct validity of the ROF scale were performed in five stages.

Deep learning for retinal vessel segmentation: a systematic review of techniques and applications.

Ophthalmic diseases are a leading cause of vision loss, with retinal damage being irreversible. Retinal blood vessels are vital for diagnosing eye conditions, as even subtle changes in their structure can signal underlying issues. Retinal vessel segmentation is key for early detection and treatment of eye diseases.

Quality of Life and Its Associated Factors Among Breast Cancer Women in Iraq: A Cross-Sectional Study.

Introduction: Breast cancer is the most prevalent cancer among women worldwide, and advancements in detection and treatment have improved survival rates. Evaluating breast cancer patients' quality of life is essential for effective healthcare planning. This study aims to assess the level of quality of life and its associated factors, including sociodemographic, clinical, coping skills, and psychological factors among breast cancer women in Iraq.

A Comparative Evaluation of the Efficiencies of Different Rotary File Systems in Terms of Remaining Dentin Thickness Using Cone Beam Computed Tomography: An In Vitro Study.

Aim: The aim of this study was to evaluate and compare the dentin thickness of the mesio-buccal canal of the lower first molar after canal preparation with three different rotary file systems using cone beam computed tomography (CBCT).

Methodology: TruNatomy (Dentsply Sirona, USA), 2Shape (Micro-Mega, France), and One Curve (Micro-Mega, France) were the three different rotary files that were employed. A total of 45 excised human permanent first mandibular molars were divided into Groups A (TruNatomy), B (2Shape), and C (One Curve) at random.

Periodontal health status, Porphyromonas gingivalis and anti-cyclic citrullinated peptide antibodies among rheumatoid arthritis patients.

Porphyromonas gingivalis (P. gingivalis) is the primary periodontal pathogen involved in protein citrullination, which triggers the production of anti-cyclic citrullinated peptide (anti-CCP) antibodies, exacerbating rheumatoid arthritis (RA). This study aims to evaluate the amount of P.

Comparative Evaluation of Fracture Resistance of Endodontically Treated Teeth Instrumented With K3XF Rotary Files Using Different Tapers.

Aim: To compare the effect of different tapers of the K3XF file system on the fracture resistance of endodontically treated mandibular premolars obturated with a three-dimensional (3-D) obturation system.

Methodology: For the study, 80 freshly extracted human mandibular premolars with single well-developed roots without any curvatures were taken and the tooth roots were wrapped in a single layer of aluminum foil, and they were placed vertically in a plastic mold filled with self-curing acrylic resin. The access was opened, and working lengths were determined.

An improved Fourier-Transform Infrared Spectroscopy combined with partial least squares regression for rapid quantification of total aflatoxins in commercial chicken feeds and food grains.

Objective: This study aims to develop and validate an Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR) spectroscopic technique combined with a partial least squares regression (PLSR) model for rapid quantification and monitoring of aflatoxins in chicken feeds and food grains.

Materials And Methods: A model of ATR-FTIR-PLSR was developed using ATR-FTIR spectra of mixed aflatoxin standards in 100% acetonitrile (112 samples) and 75% methanol (112 samples), validated by testing its prediction on 125 feed/food samples spiked with variable concentrations of aflatoxins, and applied to screen 660 samples of commercial chicken feeds and food grains from Nigerian and Malaysian markets for total aflatoxins, for which the dietary exposure risks to aflatoxins (DERA) and associated hepatocellular carcinoma (HCC) risks were evaluated for both countries.

Results: The ATR-FTIR-PLSR model demonstrated excellent prediction power [ = 99.

Multi-target weapons: diaryl-pyrazoline thiazolidinediones simultaneously targeting VEGFR-2 and HDAC cancer hallmarks.

In anticancer drug discovery, multi-targeting compounds have been beneficial due to their advantages over single-targeting compounds. For instance, VEGFR-2 has a crucial role in angiogenesis and cancer management, whereas HDACs are well-known regulators of epigenetics and have been known to contribute significantly to angiogenesis and carcinogenesis. Herein, we have reported nineteen novel VEGFR-2 and HDAC dual-targeting analogs containing diaryl-pyrazoline thiazolidinediones and their and biological evaluation.

Anti-plasmodial activity of aqueous neem leaf extract mediated green synthesis-based silver nitrate nanoparticles.

The objective of this study is to synthesize neem-silver nitrate nanoparticles (neem-AgNPs) using aqueous extracts of A. Juss for malaria therapy. Neem leaves collected from FRIM Malaysia were authenticated and extracted using Soxhlet extraction method.

Tunnel' radicular cyst and its management with root canal treatment and periapical surgery: A case report.

An untreated root canal infection usually stimulates the development of a radicular cyst. Nonsurgical root canal procedures and periapical surgery followed by placement of bone substitute will promote the healing process of the bony defect.

A single mass gathering resulted in massive transmission of COVID-19 infections in Malaysia with further international spread.

Malaysia has recorded the highest number of COVID-19 cases in Southeast Asia with more than 35% of new COVID-19 cases linked to the Sri Petaling gathering, a Moslem missionary movement attended by more than 19 000 people of different nationalities, in March 2020 in Kuala Lumpur. From this cluster, 1701 samples have been tested positive out of 21 920 tests carried out. Thus, mass gathering during COVID-19 pandemic period should be banned to curb disease transmission.

Educational needs of chronic kidney disease patients who presented to tengku ampuan afzan hospital: Preliminary findings.

Knowledge limitation is a major cause of the increasing number of chronic kidney disease (CKD) patients in Malaysia and the world. Nurses are responsible for identifying the patients' needs to come up with appropriate discharge plans which might include educational activities. The objective of this study was to determine the baseline information (socio- demographic background, as well as medical and lifestyle histories), along with educational needs of CKD patients.

Effects of Seasonal Variability on the Physicochemical, Biochemical, and Nutritional Composition of Western Peninsular Malaysia .

This study evaluated the effect of seasonal variation on the physicochemical, biochemical, and nutritional composition of . Sampling was designed during the main monsoon seasons in Malaysia-the Southwest monsoon (SWM) and Northeast monsoon (NEM)-to understand the intraspecific variation ( < 0.05).

Successful ankle replantation in two cases with different presentations.

We report our experience of treating two patients with ankle amputation with different presentations. The first case was a clean-cut sharp amputation. The second case was an avulsion injury following a motor vehicle accident in a patient who arrived 8 hours after the injury.

Breast Reconstruction After Mastectomy: A Survey of Surgeons' and Patients' Perceptions.

Background: Breast reconstruction after mastectomy is important in breast cancer care.

Materials And Methods: A cross-sectional study was designed to assess surgeons' and patients' perceptions toward breast reconstruction. Questionnaires were distributed to general and breast surgeons in East Coast Malaysian hospitals and Hospital Kuala Lumpur and to postmastectomy patients with and without breast reconstruction at the Hospital Universiti Sains Malaysia and Hospital Raja Perempuan Zainab II.

Traditional and Complementary Medicine Use in Knee Osteoarthritis and its Associated Factors Among Patients in Northeast Peninsular Malaysia.

Objectives: We sought to determine the prevalence of traditional and complementary medicine (TCM) use for knee osteoarthritis and its associated factors among patients attending a referral hospital in an eastern coastal state of Malaysia.

Methods: This cross-sectional study included 214 patients with knee osteoarthritis. A universal sampling method was applied to patients who attended the outpatient clinic in Hospital Universiti Sains Malaysia from May 2013 to October 2013.

Evaluation of Ocular Surface Disease in Asian Patients with Primary Angle Closure.

Objective: To evaluate the incidence of ocular surface disease (OSD) and to determine the effects of topical pressure-lowering drugs on ocular surface disease in primary angle closure patients.

Methods: This was a cross-sectional comparative study comparing primary angle closure glaucoma (PACG) patients (Group A) with primary angle closure and primary angle closure suspect (Group B). Group A was treated with topical pressure-lowering drugs; Group B was not.

Syphilitic uveitis: report of 3 cases.

Aim: To evaluate the clinical manifestations and visual outcome of syphilitic uveitis patients.

Methods: Case series of three patients with syphilitic uveitis who were managed in Hospital USM.

Results: Three patients were diagnosed to have uveitis secondary to Syphilis.

Extended pedicle rectus abdominis myocutaneous flap for thigh reconstruction.

A rectus abdominis myocutaneous flap can provide a large amount of tissue for defect coverage. Rarely a flabby and redundant abdominal tissue was used as a huge extended flap. We report a case of recurrence malignant fibrous histiocytoma of the thigh which was radically resected.