130 results match your criteria: "Healis-Sekhsaria Institute for Public Health[Affiliation]"

Challenges and opportunities in implementing and enforcing India's loose cigarette sales ban: A qualitative stakeholder analysis.

PLoS One

December 2024

Department of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States of America.

Introduction: Several Indian states have banned the sale of loose cigarettes, and India is considering a national ban. This study examines the perceptions of policymakers, implementers, and law enforcement officials regarding the implementation and enforcement of this ban.

Methods: Between May-October 2022, we conducted in-depth interviews with 26 key stakeholders involved in tobacco control in two Indian cities, Delhi (where the ban was not implemented) and Mumbai (where the ban was in effect).

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Introduction: Adolescent overweight and obesity as measured by body mass index (BMI) seem to be increasing at an alarming rate in urban populations. Parental BMI plays an important role in their adolescent's BMI. Overweight and obesity coexisting with undernutrition in adolescents is an important public health challenge in low- and middle-income countries (LMICs).

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Article Synopsis
  • Smokeless tobacco and areca nut consumption significantly increases the risk of oral cancer, with an estimated 120,200 cases of oral cancer in 2022 attributed to these products globally, representing about 30.8% of all oral cancer cases.
  • The majority of these cases (77%) occurred in males, with the highest rates of attributable cases found in lower-middle-income countries and specific regions like Melanesia and Southcentral Asia.
  • The study highlights that effective control measures targeting smokeless tobacco and areca nut use could prevent a substantial number of oral cancer cases worldwide.
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Background: The sale of loose cigarettes or bidis can undermine the purpose of requiring health warning labels (HWLs) on cigarette packs and bidi bundles by diminishing their visibility and legibility.

Objective: This mixed-methods study aims to examine the association between purchase behavior (loose vs pack or bundle), HWL exposure, and responses to HWLs among Indian adults who smoke.

Methods: Data were analyzed from the 2018-2019 India Tobacco Control Policy Survey and from 28 in-depth interviews conducted with Indian adults who smoked in 2022.

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Article Synopsis
  • The tobacco industry is actively working to influence tobacco control policies in India, prompting an assessment of the trends in tobacco industry interference (TII) and government responses to protect tobacco control efforts as outlined in Article 5.3 guidelines.
  • A detailed analysis covering the years 2018 to 2021 revealed a decline in India's TII score from 72 to 57, indicating some improvements in limiting interactions with the industry and avoiding conflicts, but persistent issues in regulating industry participation and transparency remain.
  • The study highlights the need for a comprehensive implementation of Article 5.3 across India, emphasizing the importance of establishing a monitoring system to continuously assess and respond to tobacco industry activities.
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Variability in addictive and carcinogenic potential of smokeless tobacco products marketed in Mumbai, India: a surveillance study.

Lancet Reg Health Southeast Asia

October 2024

Masonic Cancer Center and Division of Environmental Health Sciences, University of Minnesota, 2231 Sixth Street Southeast, Minneapolis, MN 55455, USA.

Background: India has the highest incidence worldwide of smokeless tobacco (SLT)-associated oral cancer, accounting for nearly 70% of all SLT users globally. Nicotine and tobacco-specific -nitrosamines (TSNA) play critical roles in the addictive and carcinogenic potential, respectively, of SLT products. Our group has previously reported substantial variability in nicotine and TSNA levels across a small SLT product sample in India, calling for systematic surveillance.

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Background: Anti-tobacco mass-media campaigns are an integral part of tobacco control. There is still a need to understand which mode of mass-media channels aids in promoting tobacco cessation. This study aimed to examine if exposure to anti-tobacco messages delivered through different media channels is associated with tobacco user's thoughts and attempts to quit.

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Article Synopsis
  • The study aims to provide an overview of oral cancer (OC) in India, focusing on its epidemiology, risk factors, and advancements in prevention and treatment.
  • Major risk factors for OC identified include tobacco and areca nut use, with past interventions effectively reducing tobacco-related issues, but newer carcinogenic products on the rise.
  • Despite improvements in care, OC incidence is increasing due to low awareness about quitting harmful habits and the need for screening, highlighting the need for enhanced preventive strategies.
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Introduction: Banning the sales of loose cigarettes is recommended by Article 16 of the World Health Organization - Framework Convention on Tobacco Control. This study aims to understand the perceptions of cigarette users and tobacco vendors regarding such a ban.

Methods: Using a systematic recruitment and interview protocol, we interviewed cigarette users ( = 28) and tobacco vendors ( = 28) from two Indian cities where sales of loose cigarettes were banned (Mumbai) or not banned (Delhi).

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Long-term exposure to particulate matter and all-cause and cause-specific mortality in an analysis of multiple Asian cohorts.

Environ Int

July 2024

Institute for Risk Assessment Sciences (IRAS), Utrecht University, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.

Background: Exposure to ambient air pollution is associated with a significant number of deaths. Much of the evidence associating air pollution with adverse effects is from North American and Europe, partially due to incomplete data in other regions limiting location specific examinations. The aim of the current paper is to leverage satellite derived air quality data to examine the relationship between ambient particulate matter and all-cause and cause-specific mortality in Asia.

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Background: Evidence suggests a possible link between diabetes and gastric cancer risk, but the findings remain inconclusive, with limited studies in the Asian population. We aimed to assess the impact of diabetes and diabetes duration on the development of gastric cancer overall, by anatomical and histological subtypes.

Methods: A pooled analysis was conducted using 12 prospective studies included in the Asia Cohort Consortium.

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Article Synopsis
  • A study was conducted using data from 968,738 adults across 20 cohort studies in Asia to investigate the link between diabetes and liver cancer incidence and mortality.
  • The findings revealed that adults with diabetes had a significantly higher risk of being diagnosed with liver cancer (hazard ratio of 1.97) and dying from it (adjusted hazard ratio of 1.97) compared to those without diabetes.
  • The robust results, supported by a two-stage meta-analysis, contribute valuable evidence to the understanding of liver cancer risks among diabetic populations in Asian countries.
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Article Synopsis
  • Smokeless tobacco (SLT) health warning labels in India evolved from a single symbolic warning in 2009 to larger pictorial warnings covering 85% of packaging by 2016, and this study examined their effectiveness over time.
  • Despite the changes, the 2011 updates did not significantly improve warning effectiveness, but the larger warnings in 2016 increased awareness of health risks and the desire to quit SLT among users.
  • The findings indicate that while larger images led to some improved cognitive responses, the effectiveness of health warnings can diminish over time, showing the need for continued adaptation in warning designs.
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Background: Gutkha or Paan masala with tobacco is commonly used smokeless tobacco product in India. Given the restrictions on advertisement and promotion of Gutkha and the necessity of warning labels on tobacco products, the tobacco industry has popularised paan masala without tobacco as a surrogate product. Paan masala itself is harmful for health but remains beyond scope of current tobacco control policies.

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Article Synopsis
  • Body fatness is highlighted as a potential risk factor for biliary tract cancer (BTC), with established correlations between obesity and cholelithiasis (gallstones).
  • A comprehensive analysis of data from over 905,000 participants across 21 studies in Asia found that higher body mass index (BMI) correlates with increased BTC mortality, especially in females.
  • The study indicates that while obesity is linked to BTC mortality in women without gallstones, the relationship is less clear in men and when gallstones are present, suggesting complex interactions between BMI, gender, and gallstone presence.
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Lung Cancer Risk Prediction Models for Asian Ever-Smokers.

J Thorac Oncol

March 2024

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

Introduction: Although lung cancer prediction models are widely used to support risk-based screening, their performance outside Western populations remains uncertain. This study aims to evaluate the performance of 11 existing risk prediction models in multiple Asian populations and to refit prediction models for Asians.

Methods: In a pooled analysis of 186,458 Asian ever-smokers from 19 prospective cohorts, we assessed calibration (expected-to-observed ratio) and discrimination (area under the receiver operating characteristic curve [AUC]) for each model.

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A randomised control trial was conducted among school teachers in Bihar, India for upscaling a tested, evidence-based tobacco intervention using train-the-trainer model. Six blocks in three districts were selected and randomised into intervention and control blocks. Cluster coordinators in intervention blocks were given training in the details of intervention.

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Background: This systematic review evaluated the available medical literature on the prevalence and trends of waterpipe tobacco smoking among adolescents and youth in jurisdictionally representative populations.

Methods: PubMed, Embase, and Scopus were searched for relevant studies from inception until 31 December 2022 that reported the burden of waterpipe smoking among adolescents and youth (10-24 years of age). We extracted qualitative data on the demographic characteristics, burden, and correlates of waterpipe smoking (PROSPERO ID: CRD42022310982).

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Article Synopsis
  • Lip, oral, and pharyngeal cancers pose significant global health challenges, making it essential to analyze their burden for effective health policies.
  • The study utilized data from the 2019 Global Burden of Diseases, Injuries, and Risk Factors Study to assess cancer incidence, mortality, and life years lost across 204 countries, linking these to socio-demographic factors.
  • Findings revealed approximately 370,000 cases and 199,000 deaths for lip and oral cavity cancer, and 167,000 cases and 114,000 deaths for other pharyngeal cancers in 2019, with smoking being the leading risk factor for these cancers, especially in low and middle SDI regions.
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Introduction/objective: E-cigarette use poses an additional risk for individuals who are not cigarette smokers, especially adolescents. The marketing tactics of the industry have substantially increased the prevalence of e-cigarettes, use among adolescents. India banned e-cigarette in September 2019 that has been criticized by interested groups.

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Objectives: To study the MPOWER measures over time (GATS-1 vs GATS-2) and their effects on tobacco control indicators in India.

Study Design And Methods: The study used a cross-sectional design to compare the common questions identified from GATS-1 and GATS-2. Odds ratios for various MPOWER measures were estimated using a multivariate logistic regression model.

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Background: (TFT-TFS) is an evidence-based intervention that promotes tobacco use cessation among teachers and tobacco control policies among schools in India. This study tested an implementation model to build Bihar Department of Education (DOE) capacity to support and deliver TFT-TFS within schools, leveraging DOE training infrastructure.

Method: We used a training-of-trainers (TOT) "cascade" implementation strategy to embed the TFT-TFS program into the Bihar DOE infrastructure.

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Tobacco is a threat to public health in South-East Asia and its control should be a priority. However, many common assumptions about tobacco control may not hold true for the region and can misdirect policy. The substantial health risks associated with smokeless tobacco have been largely misunderstood and neglected.

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IARC Perspective on Oral Cancer Prevention.

N Engl J Med

November 2022

From the International Agency for Research on Cancer (V.B., S.T.N., D.S., R.S., B.L.-S.), and INSERM 1052, Centre National de la Recherche Scientifique 5286, Centre de Recherche en Cancérologie de Lyon, Université Claude Bernard Lyon 1, and the Department of Medical Oncology, Centre Léon Bérard (P.S.) - all in Lyon, France; the Collaborating Centre for Oral Cancer of the World Health Organization (WHO) (S.W.) and the Faculty of Dentistry, Oral, and Craniofacial Sciences (N.W.J.), King's College London, London, the University of Sheffield School of Health and Related Research, Sheffield (O.M.), and the School of Medicine, Dentistry, and Nursing, University of Glasgow, Glasgow (D.I.C.) - all in the United Kingdom; Center for Health, Innovation, and Policy Foundation and Rollins School of Public Health, Emory University, Atlanta (R.M.); the Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD (A.K.C.); the Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei (T.H.-H.C.); Sefako Makgatho Health Sciences University, Ga-Rankuwa, and the School of Health Systems and Public Health, University of Pretoria, Pretoria - both in South Africa (O.A.A.-Y.); Healis Sekhsaria Institute for Public Health (P.C.G.) and Preventive Oncology, Karkinos Healthcare (R.S.), Navi Mumbai, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram (D.A.), Regional Cancer Centre, Trivandrum (K.R.), and the School of Preventive Oncology, Patna (D.N.S.) - all in India; New York University College of Dentistry, New York (A.R.K.); University of Peradeniya, Peradeniya, Sri Lanka (W.M.T.); the Faculty of Dentistry, University of Malaya, Kuala Lumpur (W.M.T., R.B.Z.), and MAHSA (Malaysian Allied Health Sciences Academy) University, Bandar Saujana Putra (R.B.Z.) - both in Malaysia; M.D. Anderson Cancer Center, Houston (A.G.); Griffith University Gold Coast, Southport, QLD, Australia (N.W.J.); University of São Paulo Medical School and A.C. Camargo Cancer Center (L.P.K.), São Paulo, and Piracicaba Dental School, University of Campinas, Campinas (A.R.S.-S.) - all in Brazil; the Department of Maxillofacial Surgery, School of Dentistry, Aichi Gakuin University, Nisshin, Japan (T.N.); WHO, Geneva (V.M.P., F.R.); and the Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand (P.V.).

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