Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) : A narrative review.

Background: Vestibular migraine (VM) has a wide range of clinical presentations that can have a significant negative impact on quality of life. Currently, there is no objective test available to confirm the diagnosis or measure the severity of VM. The only available tools for assessing disease severity are patient-reported outcome measures (PROMs), such as the Dizziness Handicap Inventory (DHI).

Magnetic Resonance Imaging does not distinguish Kallmann syndrome from normosmic isolated hypogonadotropic hypogonadism.

Introduction And Objectives: Isolated hypogonadotropic hypogonadism (IHH) may be associated with pituitary gland and olfactory system disorders. We aimed to correlate findings of Magnetic Resonance Imaging (MRI) of the pituitary gland and olfactory system in IHH patients with the patients' olfactory phenotype.

Patients And Methods: The present research was a single-center retrospective case-control study.

Interferon Point Alteration in Hospitalized Patients with and Without COVID-19.

Introduction: Integrating traditional Chinese medicine with Western medicine has been extensively studied in managing respiratory disease. Therefore, in this study, we aimed to examine interferon point alteration (IPA) and its association with disease severity in patients with COVID-19.

Methods: This cross-sectional study was conducted on patients hospitalized due to COVID-19 with lung involvement.

Editorial for the special issue on "microbiomes in extremes of aging".

This special issue of the Journal of Experimental Gerontology explores the dynamic interplay between microbiomes and aging-related conditions. The four selected studies highlight the role of microbiota in Alzheimer's disease, cancer immunotherapy, myocardial infarction and tryptophan metabolism, providing insights into how microbiomes influence health and disease in aging. These studies underscore the potential for microbiome-targeted interventions to mitigate aging-related disorders and improve the quality of life for older adults.

Outcomes of definitive radiotherapy vs. laryngectomy followed by adjuvant radiotherapy in patients with locally advanced laryngeal squamous cell carcinoma: real-world experience in a referral cancer center.

Background: Laryngeal cancer is a common head and neck cancer. Surgical treatment can impair patients' voice and swallowing function, making definitive radiotherapy a viable alternative for locally advanced cases.

Methods: To compare the outcomes of definitive versus adjuvant radiotherapy in patients with primary locally advanced laryngeal cancer, we retrospectively evaluated consecutive patients treated from 2007 to 2020.

Comparison between intratympanic injection of dexamethasone and methylprednisolone in idiopathic sudden sensorineural hearing loss: A randomized clinical trial.

Objective: To compare the hearing outcomes of patients with idiopathic sudden sensorineural hearing loss after intratympanic (IT) injection of methylprednisolone and dexamethasone.

Study Design: Randomized case-controlled clinical trial.

Methods: Seventy-five patients diagnosed with idiopathic sensorineural hearing loss were randomly divided into two groups based on therapy.

The Outcomes of Cochlear Implantation in Patients with Solid Organ Transplant.

Introduction: As far as it is known, long-lasting immunosuppressive therapy might put patients with solid organ transplantation (SOT) at increased risk for severe to profound sensorineural hearing loss, eventually leading to cochlear implantation (C.I). So, the main aim of the present study is to evaluate their auditory perception performance after cochlear implantation.

[18F]FDG PET/CT Imaging and Hematological Parameters Can Help Predict HPV Status in Head and Neck Cancer.

Objective: To determine whether [F]FDG PET/CT and hematological parameters provide supportive data to determine HPV status in HNSCC patients.

Methods: Retrospective analysis of clinical and diagnostic data from 106 patients with HNSCC: 26.4% HPV-positive and 73.

Expert perspectives for transoral robotic versus laser surgery for supraglottic carcinomas.

Objective: To assess the opinion, practices, and challenges of international key opinion leaders about two minimal invasive surgical techniques in supraglottic laryngeal tumours: transoral laser microsurgery (TLM) and the transoral robotic surgery (TORS).

Methods: Design of a questionnaire composed of seven sections and fifty questions covering descriptive data of participants, practitioners experience procedural sequences, considerations related to airways, feeding, and voice, intraoperative haemorrhage, postoperative management, and a comparative analysis of TLM and TORS in treating supraglottic laryngeal cancer.

Results: A total of 27 head and neck surgeons replied to the survey.

Comparison of serum zinc levels between patients with sinonasal neutrophilic and eosinophilic inflammatory polyposis and healthy individuals.

Objectives: Some changes in nasal mucus and paranasal sinuses may occur due to zinc deficiency, which can cause chronic rhinosinusitis with nasal polyps (CRSwNP). The current study was designed to compare the serum zinc concentration between patients with chronic rhinosinusitis complicated with eosinophilic or neutrophilic nasal polyps and a control group.

Methods: A total of 105 patients participated in the study.

EXOSOMES FROM CYCLIC MICE MODULATE LIVER TRANSCRIPTOME IN ESTROUPAUSE MICE INDEPENDENT OF AGE.

Background: Exosomes are extracellular vesicles secreted by cells that contain microRNAs (miRNAs). These miRNAs can induce changes in gene expression and function of recipient cells. In different cells exosome content can change with age and physiological state affecting tissues function and health.

The diagnostic performance of cochlear endolymphatic hydrops and perilymphatic enhancement in stratifying Ménière's disease probabilities: A meta-analysis of semi-quantitative MRI-based grading systems.

Background: The diagnosis of Meniere's Disease (MD) presents significant challenges due to its complex symptomatology and the absence of definitive biomarkers. Advancements in MRI technology have spotlighted endolymphatic hydrops (EH) as a key pathological marker, necessitating a reevaluation of its diagnostic utility amidst the need for standardized and validated MRI-based grading scales.

Methods: Our meta-analysis scrutinized the diagnostic efficacy of semi-quantitative MRI-based cochlear endolymphatic hydrops (EH) and perilymphatic enhancement (PLE) grading systems in delineating clinically relevant discriminations: "Spotting" the shift from normal or asymptomatic ears to possible/probable MD (pMD), "Confirming" the progression to definite MD (dMD), and "Establishing" the presence of dMD.

The Effect of Total Thyroidectomy on Trace Elements, Namely Zinc and Copper in Patients with Thyroid Diseases.

The aim of this study was to investigate the effect of total thyroidectomy on serum levels of trace elements, namely zinc and copper, in patients with thyroid diseases. In this cross-sectional study, 42 patients with thyroid diseases according to laboratory and fine needle aspiration (FNA) results divided into two groups, including differentiated thyroid cancer group (papillary and follicular) and non-cancerous group (MNG: Multinodular goiter). Before the surgery, blood sample was taken to investigate the zinc and copper levels.

Contralateral Ear in Patients with Chronic Otitis Media.

To evaluate the opposite ear in patients operated for chronic otitis media (COM). In a cross-sectional study involving three tertiary hospitals, patients who underwent surgery for COM were examined for abnormalities of the contralateral ear at the time of the surgery. Out of 228 patients, 182 (79.

Comparison of Supra-Alar Crease Deepening Following Septorhinoplasty in Two Techniques: Lateral Crura Steal Versus Lateral Crura Overlay.

Background: Nasal tip correction is one of the most challenging parts of rhinoplasty. The objective of the study was to compare the prevalence of supra-alar crease deepening in lateral crura steal (LCS) and lateral crura overlay (LCO) techniques.

Methods: In this prospective study, eligible patients referred to a university hospital for septorhinoplasty during 2022 were included.

Environmental factors and the incidence of pediatric epistaxis: A systematic review with meta-analysis.

Background: A growing body of literature explores environmental risk factors for pediatric epistaxis, yielding variable results. We aim to clarify these associations through a systematic review and meta-analysis.

Methods: PubMed, Scopus, Cochrane Central Register of Control Trials, Web of Science, Medline, Google Scholars, and Embase were systematically searched up to April 2024.

Evaluation of Dentofacial Angles in Children with Severe Adenoid Hypertrophy.

Introduction: Hypertrophy of adenoids is a common condition in childhood, resulting in obstructive symptoms such as sleep apnea, snoring, and rhinosinusitis. Adenotonsillectomy is recommended to improve prognosis and quality of life. This case-control study compared facial angles and lip position related to dentofacial and mouth growth in symptomatic children with adenoid hypertrophy and asymptomatic control groups.

Effect of senolytic drugs in young female mice chemically induced to estropause.

Aims: This study aimed to assess metabolic responses and senescent cell burden in young female mice induced to estropause and treated with senolytic drugs.

Main Methods: Estropause was induced by 4-vinylcyclohexene diepoxide (VCD) injection in two-month-old mice. The senolytics dasatinib and quercetin (D + Q) or fisetin were given by oral gavage once a month from five to 11 months of age.

Geniculate ganglion diverticulum: a potential imaging marker in patients with idiopathic intracranial hypertension.

Purpose: The diagnosis of idiopathic intracranial hypertension (IIH) is often challenging in patients who do not present with classic symptoms. Brain MRI can play a pivotal role, as several imaging findings, such as an empty sella appearance (ESA), have been shown to be associated with IIH. Yet, none of the MRI signs have been shown to have a high sensitivity and specificity.

Exploring the Association of Serum Uric Acid Levels with Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis.

The role of uric acid in pathogenesis of benign paroxysmal positional vertigo (BPPV) is not fully understood. It is aimed to assess the serum uric acid levels in BPPV patients compared to healthy controls. Systematic review and meta-analysis.