217,132 results match your criteria: "Head Injury"

Chuanxiong Qingnao Granules (CQG) alleviates nitroglycerin-induced migraine-like pain in rats by glycerophospholipid metabolism and PI3K/Akt signaling pathway.

Phytomedicine

December 2024

Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address:

Background And Purpose: Chuanxiong Qingnao Granles (CQG), has been used to treat migraine headache (MH) for many years. However, current investigation of CQG have primarily focused on clinical studies, and the potential mechanisms underlying of its effects on MH have not been fully elucidated. In the present study, we applied an integrated approach of transcriptomics and metabolomics to elucidate the therapeutic mechanisms of CQG in nitroglycerin (NTG)-induced MH injury.

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A high-performance core laboratory GFAP/UCH-L1 test for the prediction of intracranial injury after mild traumatic brain injury.

Am J Emerg Med

December 2024

Warfighter Readiness, Performance, and Brain Health Project Management Office (WRPBH PMO), US Army Medical Materiel Development Activity (USAMMDA), 1430 Veterans Drive, Fort Detrick, MD 21702, USA.

Background: A glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) blood biomarker panel can reliably eliminate the need to perform a head computed tomography (CT) scan in selected patients with traumatic brain injury (TBI). Currently, this FDA cleared panel can be run both on a core laboratory platform or a hand-held single-sample point of care platform. This study examined test characteristics of the panel as analyzed on a core lab-based fast high-throughput platform.

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Long-term effects of concussion on attention, sensory gating and motor learning.

Exp Brain Res

December 2024

Department of Kinesiology and Health Sciences, University of Waterloo, 200 University Ave. W, Waterloo, ON, N2L 3G1, Canada.

The current work aimed to understand the behavioral manifestations that result from disruptions to the selective facilitation of task-relevant sensory information at early cortical processing stages in those with a history of concussion. A total of 40 participants were recruited to participate in this study, with 25 in the concussion history group (Hx) and 15 in the control group (No-Hx). Somatosensory-evoked potentials (SEPs) were elicited via median nerve stimulation while subjects performed a task that manipulated their focus of attention toward or away from proprioceptive cues.

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Introduction: Hip fractures are common in elderly patients, often accompanied by comorbidities. These fractures can be combined with other injuries, such as a femoral head, neck, or shaft dislocation. The cause of this complex injury is not well-established, but factors like high-energy trauma or falls from a certain height may contribute.

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Pediatric neck injuries associated with trampoline use.

Am J Otolaryngol

December 2024

Department of Otolaryngology-Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14209, USA. Electronic address:

Objective: Trampolines are popular among children, but trampoline injuries constitute a large number of emergency department visits. The purpose of this study was to determine how often neck injuries occur among children with trampoline-related injuries and to identify the mechanism of injury.

Methods: We analyzed the National Electronic Injury Surveillance System (NEISS) database to characterize patient demographics, injury types, injury subsite, and emergency department disposition status associated with trampoline related neck injuries between 2012 and 2021 in the United States.

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Case: A 60-year-old man presented with a chronic right pectoralis major muscle belly tear of the lower sternal head that was missed and previously treated with tendon repair of the sternal and clavicular heads. The tear was repaired and reconstructed with an Achilles allograft. At the 1.

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Activity-Based Proteome Profiling of Serum Serine Hydrolases: Application in Pediatric Abusive Head Trauma.

Proteomics Clin Appl

December 2024

Faculty Unit of Toxicology, University Center of Legal Medicine, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

Purpose: Traumatic brain injury (TBI), including pediatric abusive head trauma (AHT), is the leading cause of death and disability in children and young adults worldwide. The current understanding of trauma-induced molecular changes in the brain of human subjects with intracranial hemorrhage (ICH) remains inadequate and requires further investigation to improve the outcome and management of TBI in the clinic. Calcium-mediated damage at the site of brain injury has been shown to activate several catalytic enzymes.

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Defining the Thyroid-RLN Entry Triangle for Enhanced Recurrent Laryngeal Nerve Exposure in TOETVA: A Retrospective Study.

J Otolaryngol Head Neck Surg

December 2024

Department of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, P.R. China.

Background: Injury to the recurrent laryngeal nerve (RLN) and parathyroid glands (PGs) are the most common and serious complications during the transoral endoscopic thyroidectomy vestibular approach (TOETVA), and their exposure and protection are the most important factors affecting the operation time. Here, we report a novel anatomical landmark and surgical method to shorten the operative time and reduce the chance of injury to the RLN and PGs.

Methods: According to the different exposure methods of the RLN, patients were divided into the experimental group (from top to bottom, E-group) and the comparison group (from outside to inside, C-group), and 1:1 propensity score-matching (PSM) was performed.

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This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To determine the benefits and harms of injury prevention programmes on anterior cruciate ligament injuries.

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Objective: To evaluate characteristics associated with increased cost and length of hospitalization of mandible fracture management.

Study Design: Retrospective chart review.

Methods: Demographics, injury mechanism, associated injuries, treatment information, and associated costs were collected for all patients treated for mandible fracture treated at a single institution over a 14-year period.

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Corneal alkali burns persist as a significant challenge in our field, often leading to a prolonged treatment course with various sight-threatening problems. This work, of utmost importance, aimed to apply the photo-tissue bonding technique (PTB) to weld the amniotic membrane (AM) to the corneal surface versus an amniotic membrane graft (AMG) and explore its safety in saving corneal protein against alkali burn.Methods Twenty-seven rabbits with an induced corneal ulcer using 1 mol/L NaOH solution.

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Objective: To investigate the correlation between neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in neurosurgery and their impact on the occurrence and prognosis of acute traumatic progressive hemorrhagic brain injury (PHI) among traumatic brain injury patients.

Method: A retrospective analysis encompassed 220 traumatic brain injury patients treated between 2019 and 2022. Patients were categorized into two groups: those experiencing progressive hemorrhagic brain injury (PHI) and those without PHI.

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Injury epidemiology in Australian women's professional football.

J Sci Med Sport

November 2024

Football Australia, Australia; School of Sport, Exercise and Rehabilitation, Faculty of Health, University of Technology Sydney, Australia.

Objective: To describe the injury epidemiology of the Australian women's professional football (soccer) league (A-League W) over 7 consecutive seasons.

Design: Prospective observational cohort study.

Methods: Match-loss injury data was collected from each A-League W club (n = 8-9) for each competition round (n = 12/season) over 7 seasons (2013/14-2019/20).

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Chronic carbendazim exposure disrupts behavioral responses and redox-regulatory mechanisms in non-target detritivore Nauphoeta cinerea nymphs.

Environ Toxicol Pharmacol

December 2024

Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Carbendazim is widely applied in agriculture to control various fungal diseases during pre-harvest and post-harvest processes owing to its efficacy and cost-effectiveness. However, environmental and food contamination by carbendazim has become a global health issue. Indeed, the declining biodiversity of beneficial insects owing to agricultural intensification is currently of keen concern to the scientific community.

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Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring.

Neuroimage

December 2024

Department of Anesthesiology and Intensive Care Medicine, Technical University of Munich, School of Medicine, 81675 Munich, Germany.

Background: Cortical high-frequency activation immediately before death has been reported, raising questions about an enhanced conscious state at this critical time. Here, we analyzed an electroencephalogram (EEG) from a comatose patient during the dying process with a standard bedside monitor and spectral parameterization techniques.

Methods: We report neurophysiologic features of a dying patient without major cortical injury.

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Physical and psychosocial consequences of falls in ambulatory individuals with cerebral palsy by age and gross motor function.

Arch Phys Med Rehabil

December 2024

Gillette Children's - James R. Gage Center for Gait and Motion Analysis, Saint Paul, Minnesota, USA; University of Minnesota - Twin Cities, Department of Orthopedic Surgery, Minneapolis, Minnesota, USA. Electronic address:

Objective: To quantify physical and psychosocial impacts of falls by age and Gross Motor Classification System (GMFCS) level in ambulatory individuals with cerebral palsy (CP).

Design: Cross-Sectional Survey.

Setting: Tertiary specialty hospital and online CP communities.

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Purpose: The role of neoadjuvant chemotherapy in locally advanced sinonasal squamous cell carcinoma (SNSCC) has not been established prospectively. We conducted a phase II trial of neoadjuvant chemotherapy (NAC) with docetaxel/cisplatin/5-fluorouracil (TPF) in this population.

Materials And Methods: Eligible patients had unresectable, locally advanced SNSCC, defined as T3/4 stage or potential compromise of critical organ function on surgery.

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Rational approach to fetal heart rate monitoring and management during the second stage of labor.

Eur J Obstet Gynecol Reprod Biol

December 2024

Direttore UOC Ostetricia e Ginecologia, Azienda Ospedaliera Universitaria di Parma, Professore Ordinario di Ginecologia e Ostetricia, Direttore della Scuola di Specializzazione in Ostetricia e Ginecologia, Presidente del CdS OstetriciaUniversità di Parma, Italy. Electronic address:

Second stage of labor is considered to be associated with an increased risk of intrapartum fetal hypoxic injury. This is due to a combination of several risk factors such as -the increased frequency, strength and duration of uterine contractions due to higher number and affinity of myometrial oxytocin receptors; -the Ferguson's reflex which leads to a reflex release of endogenous oxytocin in response of the distension of the cervix by descending fetal head in late stages of labor; maternal expulsive efforts with the Valsalva manoeuvre that may reduce maternal oxygenation, as well as reduce the venous return and maternal cardiac output due to increased intrathoracic pressure, winch may lead to reduced placental oxygenation; - and increased fetal intracranial pressure due to head compression leading to a potential decrease in fetal cerebral oxygenation. In addition, the umbilical cord often forms one or more loops around the fetal neck, which may get tightened as the head descends leading to an acute and intermittent cessation of fetal oxygenation.

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Introduction: This study describes and analyzes the distribution of fall cases documented in the National Injury Surveillance System (NISS) from 2019 to 2022.

Methods: Fall data from the NISS (2019-2022) were descriptively analyzed by gender and age.

Results: The NISS in China reported 2,324,577 fall cases from 2019 to 2022.

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Art therapy and brain injury: making the invisible visible.

Front Psychol

December 2024

College of Nursing and Health Professions, Art Therapy and Counseling, Drexel University, Philadelphia, PA, United States.

The multiple cognitive, somatic, and behavioral changes following head injuries can result in expressive language difficulties that may not be resolved quickly. This paper explores the traumatic brain injury and post-concussive syndrome artwork created by an art therapist and the child of an art therapist, making the invisible neurological consequences of head injuries visible. Our first-person and caregiver perspectives offer examples of visual arts-based communication between patients, health professionals, and family members.

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Arthrosurface of the humeral head with the OVO surface replacement endoprosthesis.

J Surg Case Rep

December 2024

Clinical Department of Orthopedics, Plac Medyków 1, 41-214 Sosnowiec, Silesia, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Poniatowskiego 15, 40-055 Katowice, Silesia, Poland.

The case report concerns a 67-year-old man who suffered an accident on a motorcycle, as a result of which he suffered a dented fracture of the right humeral head. After physical examination and imaging diagnostics, he was qualified for surgical treatment-arthrosurface of the patient's humeral head with the OVO surface replacement endoprosthesis. Right after the patient's surgical treatment, a period of 16-week rehabilitation was implemented, which, as a result, enabled the patient to achieve a full range of shoulder mobility, and the patient was able to return to all activities before the injury.

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Concussion is a common injury in rugby union ('rugby') and yet its diagnosis is reliant on clinical judgment. Oculomotor testing could provide an objective measure to assist with concussion diagnosis. NeuroFlex® evaluates oculomotor function using a virtual-reality headset.

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Grayken Lessons: a patient who developed opioid use disorder after traumatic brain injury.

Addict Sci Clin Pract

December 2024

Grayken Center for Addiction, Clinical Addiction Research and Education (CARE) Unit, Section of General Internal Medicine, Department of Medicine, School of Medicine, Boston Medical Center, Boston University, Boston, MA, USA.

Background: Traumatic brain injury (TBI) is common in people with substance use disorders (SUDs). TBI often results in cognitive deficits which can affect the clinical course of SUD.

Case Presentation: Here we present the case of a 34-year-old Spanish-speaking man with severe opioid use disorder and two prior TBIs affecting his cognitive abilities.

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Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs.

J Neuroinflammation

December 2024

Center for Brain Injury & Repair, Department of Neurosurgery, University of Pennsylvania, 105 Hayden Hall, 3320 Smith Walk, Philadelphia, PA, 19104, USA.

Traumatic brain injury (TBI) is a global health problem affecting millions of individuals annually, potentially resulting in persistent neuropathology, chronic neurological deficits, and death. However, TBI not only affects neural tissue, but also affects the peripheral immune system's homeostasis and physiology. TBI disrupts the balanced signaling between the brain and the peripheral organs, resulting in immunodysregulation and increasing infection susceptibility.

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