14 results match your criteria: "Havering and Redbridge University NHS Trust[Affiliation]"

Article Synopsis
  • The study analyzed the adverse effects of using isosulfan blue dye in sentinel lymph node mapping for breast cancer, reviewing data from Medline and Embase.
  • The overall adverse event rate was found to be low at 11.65 events per 1,000 patients, with the most common issue being mild allergic skin reactions (Grade I).
  • Intraparenchymal administration had a higher adverse event rate than peritumoral injection, but both methods resulted in low overall risk, suggesting that isosulfan is a safe option for clinicians in SLN mapping.
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Introduction: Technical advances and the increasing role of interdisciplinary decision-making may warrant formal definitions of expertise in surgical neuro-oncology.

Research Question: The EANS Neuro-oncology Section felt that a survey detailing the European neurosurgical perspective on the concept of expertise in surgical neuro-oncology might be helpful.

Material And Methods: The EANS Neuro-oncology Section panel developed an online survey asking questions regarding criteria for expertise in neuro-oncological surgery and sent it to all individual EANS members.

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Robotic platforms provide a stable tool with high-definition views and improved ergonomics compared to laparoscopic approaches. The aim of this retrospective study was to compare the intra- and short-term postoperative results of oncological resections performed robotically (RCR) and laparoscopically (LCR) at a single centre. Between February 2020 and October 2022, retrospective data on RCR were compared to LCR undertaken during the same period.

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Background: The objective of this comprehensive pan-cancer study is to evaluate the potential of deep learning (DL) for molecular profiling of multi-omic biomarkers directly from hematoxylin and eosin (H&E)-stained whole slide images.

Methods: A total of 12,093 DL models predicting 4031 multi-omic biomarkers across 32 cancer types were trained and validated. The study included a broad range of genetic, transcriptomic, and proteomic biomarkers, as well as established prognostic markers, molecular subtypes, and clinical outcomes.

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Article Synopsis
  • Around 5-20% of patients with advanced gastric cancer (AGC) develop peritoneal carcinomatosis, leading to a high recurrence rate and poor prognosis, prompting research into hyperthermic intraperitoneal chemotherapy (HIPEC).
  • A meta-analysis of 16 studies involving 1700 AGC patients revealed that HIPEC significantly improves overall survival and reduces recurrence rates without increasing complications, although it does show a higher risk of postoperative renal dysfunction.
  • The findings suggest that HIPEC can be beneficial for AGC patients, enhancing 3 and 5-year survival rates while maintaining manageable complication levels.
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Retroperitoneal tumors are rare neoplasms that can reach great dimensions due to a slow growth pattern. Although these tumors rarely metastasize, they have a great risk of recurrence, and majority of times these lesions are a challenge for the surgeon. We report the case of a 63-year-old woman who presented with symptoms of large bowel obstruction and was diagnosed with a large heterogenous mass located in the retroperitoneal space.

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We can reduce negative paediatric appendicectomy rate: A cohort study.

Ann Med Surg (Lond)

November 2021

Department of General Surgery, Queen's and King George's Hospital, Barking, Havering and Redbridge University NHS Trust, United Kingdom.

Background: Appendicitis accounts for the most frequent surgical emergencies in childhood. The guidance from the Royal College of Surgeons and poor post operative outcomes in surgical patients during the pandemic, it would be expected that only children who had clinical signs of appendicitis and were unwell, would have undergone surgery. Hence, the negative appendicectomy rate during the pandemic should have decreased.

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The COVID-19 pandemic had a significant effect on healthcare globally. Additional pressure created by coronavirus adversely affected the mental health and psychological well-being of healthcare workers, leading many to question their desire and willingness to continue working in healthcare. This study aimed to identify predictors for career change ideation among healthcare professionals in two countries; Lithuania and the United Kingdom amid the coronavirus pandemic.

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Clinical performance of Determine HBsAg 2 rapid test for Hepatitis B detection.

J Med Virol

December 2020

Barts Liver Centre, Barts and The London School of Medicine and Dentistry, Blizard Institute, London, UK.

Hepatitis B virus (HBV) infection is estimated to affect 292 million people worldwide, 90% of them are unaware of their HBV status. The Determine HBsAg 2 (Alere Medical Co, Ltd Chiba Japan [Now Abbott]) is a rapid test that meets European Union (EU) regulatory requirements for Hepatitis B surface antigen 2 (HBsAg) analytical sensitivity, detecting the 0.1 IU/mL World Health Organization (WHO) International HBsAg Standard.

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Surgery for epilepsy dates back to 1886 and has undergone significant developments. Today it is considered a key treatment modality in patients who are resistant to pharmacological intervention. It improves seizure control, cognition and quality of life.

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Background: Antiepileptic treatment strategy plays an important role in the management of intracranial vascular malformations. The intracranial vascular malformations can be divided into cavernous hemangiomas, arteriovenous malformations, developmental venous anomalies and capillary telangiectasias. Seizures and hemorrhage are among their most common clinical manifestations.

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BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis.

Rheumatology (Oxford)

December 2014

Department of Rheumatology, Norfolk and Norwich University Hospitals Foundation NHS Trust, Norwich, Medical School, University College London, London, City Hospital, Birmingham, Barking, Havering and Redbridge University NHS Trust, Romford, St Thomas' Hospital, London, University of Birmingham, Birmingham, Addenbrooke's Hospital, Cambridge, Nuffield Orthopaedic Centre, Oxford, Vasculitis UK, Matlock, School of Nursing and Midwifery, University of East Anglia, Norwich, Central Manchester Foundation Trust, Manchester, Ipswich Hospital NHS Trust, Ipswich and Norwich Medical School, University of East Anglia, Norwich, UK. Department of Rheumatology, Norfolk and Norwich University Hospitals Foundation NHS Trust, Norwich, Medical School, University College London, London, City Hospital, Birmingham, Barking, Havering and Redbridge University NHS Trust, Romford, St Thomas' Hospital, London, University of Birmingham, Birmingham, Addenbrooke's Hospital, Cambridge, Nuffield Orthopaedic Centre, Oxford, Vasculitis UK, Matlock, School of Nursing and Midwifery, University of East Anglia, Norwich, Central Manchester Foundation Trust, Manchester, Ipswich Hospital NHS Trust, Ipswich and Norwich Medical School, University of East Anglia, Norwich, UK.

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Early spondyloarthritis in multiracial society: differences between gender, race, and disease subgroups with regard to first symptom at presentation, main problem that the disease is causing to patients, and employment status.

Rheumatol Int

June 2012

Department of Rheumatology and Rehabilitation, Barking Havering and Redbridge University NHS Trust, King George Hospital, Barley Lanes, Goodmayes, Ilford, Essex, London, IG3 8YB, UK.

To determine whether the first presenting symptoms, the main problem that the disease is causing to patients, and the employment status at presentation of patients with early spondyloarthritis (SpA) in a multicultural/multiracial patient cohort are different between gender, race, and disease subgroups of the SpA spectrum (ankylosing spondylitis, enteropathic arthritis, psoriatic arthritis, or undifferentiated arthritis). All patients above the age of 16 years, with disease duration of less than 3 years since symptom onset, seen in clinic between 2004 and 2008 with spondyloarthritis (SpAs) were assessed regarding their first presenting symptom, the main problem caused by the disease, and their employment status. In addition, clinical parameters such as the degree of disease activity (measured by BASDAI, ESR, and CRP), functional ability (measured by BASFI), night pain, sleep disturbance, well-being over past week, and over past 6 months prior to assessment (measured by a 10 cm VAS; 0 = good health, 10 = worst possible) were obtained.

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