Cardiovascular Screening before Sports Participation: Results of 11487 Children.

Aim: In this study, it is aimed to analyze the data of children who were referred to our clinic for pre-participation sports screening.

Methods: Data, between September 2017 and December 2021, had been analyzed. All these subjects had been questioned for their personal and family medical stories and examined for cardiovascular system findings.

Efficacy and Safety of Trastuzumab Emtansine in Her2 Positive Metastatic Breast Cancer: Real-World Experience.

Aim: The aim of this study is to evaluate the efficacy and toxicity of trastuzumab emtansine (T-DM1) in cases with metastatic breast cancer (mBC) in different lines of treatment.

Method: Retrospective analysis of T-DM1 results of human epidermal growth factor receptor 2 (Her2) positive 414 cases with mBC from 31 centers in Turkey.

Findings: Except 2, all of the cases were female with a median age of 47.

The relationship between resilience, moral sensitivity, and cultural competence among nurses.

This study aimed to examine the relationships between resilience, moral sensitivity, and cultural competence among nurses. A descriptive correlational design was employed. The study comprises 120 nurses.

Prisoners seeking healthcare in emergency department.

Objective: To evaluate inmate referrals to emergency department of a tertiary healthcare facility in terms of demographical and clinical characteristics as well as their impact on the department.

Methods: The retrospective cross-sectional study was conducted at Ankara Numune Training and Research Hospital, Ankara, Turkey and comprised data of incarcerated patients who were brought to the emergency department from January 01, 2010, to December 31, 2012. Demographical characteristics, consultations, duration of hospitalisation, recurrent admissions, disposal and mortality rates were noted.

Lack of association between obstructive sleep apnea syndrome and specular microscopic features of the corneal endothelium.

Background: Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of hypoxemia and hypercapnia during sleep. The aim of this study was to determine whether OSAS causes significant changes in corneal endothelium detectable by specular microscopy.

Methods: This prospective, cross-sectional study compared the specular microscopic features of the corneal endothelium of patients with OSAS and age-and gender-matched controls.

Evaluation of sleep quality and restless legs syndrome in adult patients with sickle cell anemia.

Purpose: To determine the prevalence of poor sleep quality and RLS in adult patients with sickle cell anemia (SCA). The second aim was to identify the risk factors for RLS and impairment of sleep quality in SCA patients.

Materials And Methods: Patients at least 18 years old, with hemoglobin electrophoresis confirmation of sickle cell disease, were included.

Utility of brain fluorodeoxyglucose PET in children with possible autoimmune encephalitis.

Purpose: We aimed to explore the utility and additional clinical contribution of brain fluorodeoxyglucose (FDG) PET imaging for the assessment of children with possible autoimmune encephalitis in comparison to brain MRI.

Materials And Methods: We conducted a retrospective analysis of six pediatric patients (all seronegative) between 2014 and 2019 with the initial diagnosis of possible autoimmune encephalitis who had brain FDG PET/CT or PET/MRI and brain MRI during the diagnostic period. Diagnosis of possible autoimmune encephalitis was based on clinical consensus criteria defined by Graus et al.

Plasma homocysteine levels in patients with keratoconus.

Background: To compare the plasma levels of homocysteine between patients with keratoconus and healthy subjects.

Methods: Thirty-three keratoconus patients, and 47 age-gender matched healthy subjects were included in this prospective study. The plasma level of homocysteine, folic acid, and vitamin B12 was assessed using the chemiluminescence immunometric method.

Do physicians measure patients' blood pressure, and are those measurements reliable?

To determine how and how often blood pressure (BP) measurement is performed in health institutions. The researchers observed whether or not 84 physicians performed BP measurement. Immediately after BP measurement by the physician, this was repeated by the researchers in a manner compatible with HT guidelines.

The Relation Between Variability of Intact Parathyroid Hormone, Calcium, and Cardiac Mortality in Hemodialysis Patients.

Chronic kidney disease-mineral and bone disorder (CKD-BMD) is a condition known to be associated with cardiovascular disease and mortality in hemodialysis (HD) patients. The relation between calcium (Ca), phosphorus (P), and intact parathyroid hormone (iPTH) variability in HD patients and cardiac mortality is unknown. The purpose of this study was to assess the relation between variability in these parameters and cardiac mortality.

Latent polyglandular autoimmune syndrome type 2 case diagnosed during a shock manifestation.

There are many types of polyglandular autoimmune syndrome (PAS). PAS type 2 is the most common type among adults. For PAS type 2 (PAS-2) diagnosis, detection of Addison's disease with autoimmune thyroid disease and/or type 1 diabetes mellitus are required.

A new player in chronic kidney disease mineral and bone disorder: tenascin-C.

Aims: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a condition frequently observed in CKD. The search for a reliable and easy to use biomarker in the diagnosis of CKD-MBD is continuing. Tenascin-C (TN-C) is an important extracellular (ECM) protein synthesized by osteoblasts during bone growth and morphogenesis.

Will a second biopsy sample affect treatment decisions in patients with chronic hepatitis B?

Background And Aim: Liver biopsy is the gold standard for assessment of fibrosis in patients with hepatitis B. However, it has some disadvantages, including inter-observer and intra-observer variability in biopsy interpretation and specimen variation. A standard biopsy specimen represents only about 0.

A new predictor of mortality in hemodialysis patients; Tenascin-C.

Aim: Cardiovascular disease is the most frequent cause of mortality in hemodialysis patients. There are a number of inconsistencies in terms of cardiovascular risk factors in these patients. Tenascin C (TN-C) is a matricellular protein which may be a prognostic predictor after myocardial infarction and many cardiac diseases.

A case of renal failure developing in association with African mango consumption.

Chronic kidney disease continues to represent a significant health problem in all societies. One of the main factors accelerating renal progression is nephrotoxins. The African mango is a plant added to many foods and commonly consumed in West Africa.

Can be galectin-3 a novel marker in determining mortality in hemodialysis patients?

Background: Cardiovascular (CV) mortality is common in hemodialysis (HD) patients. There are some difficulties involved in determining CV risk. Galectin-3 is a molecule with a demonstrated correlation with CV mortality and which is approved in the stratification of heart failure (HF) risk.

A case of rectal adenocarcinoma presented with palatine tonsil metastasis.

The most common metastatic sites of colorectal cancer are liver, lung, peritoneum and lymph nodes. Metastasis of colorectal carcinoma to palatine tonsil is rarely seen. To our knowledge, only 11 patients were documented in English literature.

Serum endocan levels in patients with chronic liver disease.

Background And Aim: Early detection of fibrosis should be the main goal of treatment in liver cirrhosis. Endocan, previously called endothelial cell specific molecule-1, is expressed by endothelial cells, primarily in the lung, liver and kidney. In this study, we aimed to examine the correlation of liver fibrosis stage, histological activity and grade of steatosis between serum levels of endocan in patients with chronic hepatitis B (CHB), chronic hepatitis C (CHC) and non-alcoholic fatty liver disease (NAFLD).

The effects of nitrous oxide on vascular endothelial growth factor (VEGF) and its soluble receptor 1 (VEGFR1) in patient undergoing urological surgery.

Objective: Anesthesia and surgical intervention, leads to the development of systemic inflammatory response. The severity of the inflammatory response depends on the pharmacological effects of anesthetic agents and duration of anesthesia. OBJECTIVE of the study was to investigate the effect of nitrous oxide on VEGF and VEGFR1 levels in patients undergoing surgery.

Can serial monitoring of serum Vascular Endothelial Growth Factor (VEGF), Nitric Oxide (NO), and Angiotensin II (ANGII) levels have predictive role during Bevacizumab treatment?

Background: Standard treatment of colorectal cancer includes both cytostatic chemotherapy and targeted therapies. Bevacizumab, targeting the VEGF receptor, is one of the primary targeted therapies that achieve better response rate and survival rate as compared to combination chemotherapy. To the best of our knowledge, there is no established single marker that can be used as a predictive marker in bevacizumab therapy.

A rare metastatic region of cervix cancer; the brain.

Cervical cancer is a frequent malignancy of the females. It still remains a leading cause of cancer-related death in women world wide. Cervical cancers do not always spread, but those that do most often spread to the lungs, liver, bladder, and vagina.

Comparison of standardized uptake values obtained from two- and three-dimensional modes of fluorine-18 fluorodeoxyglucose PET-CT in oncological cases.

Purpose: We investigated the usability of standardized uptake values (SUV) obtained from both two- and three-dimensional (2D and 3D) positron-emission tomography and computed tomography (PET-CT) imaging, and compared the images obtained from these techniques in terms of image quality, lesion detectability, and the presence of artifacts.

Materials And Methods: Image data from 100 patients, who had undergone two PET imagings obtained in 2D and 3D mode after a low dose CT, were evaluated prospectively. Subjective analysis of 2D and 3D images was performed by two readers evaluating the following criteria: overall image quality, detectability of each identified lesion, and the presence of artifacts.