731 results match your criteria: "Hasan-Sadikin General Hospital[Affiliation]"

Background: This study is to compare the time to pregnancy (TTP) between patients with endometriosis and nonendometriosis undergoing fertilisation (IVF).This is an observational retrospective cohort study. We included 291 patients (53 with endometriosis and 238 without endometriosis) achieving biochemical pregnancy, whether singleton or multifetal (serum beta-hCG >5 mIU/mL), between 1st January 2014 and 31st March 2020.

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Efficacy and safety of rucaparib in patients with recurrent high-grade ovarian carcinoma: A systematic review and meta-analysis.

Taiwan J Obstet Gynecol

September 2024

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Padjadjaran University, Dr. Hasan Sadikin General Hospital, Jl. Pasteur No.38, Pasteur, Bandung, West Java, 40161, Indonesia.

Ovarian cancer stands as the third most prevalent gynecological malignancy. The advent of PARP inhibitors, particularly rucaparib, has revolutionized the landscape of advanced ovarian cancer treatment, demonstrating notable efficacy with minimal toxicity, especially in patients not previously exposed to PARP inhibitors. Rucaparib's precision-driven approach, targeting specific genetic mutations, disrupts DNA repair mechanisms, resulting in cytotoxic effects on neoplastic cells.

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Intraabdominal mature cystic teratoma in a 20-year-old male: A rare case.

Radiol Case Rep

November 2024

Department of Anatomical Pathology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.

Teratomas are the most prevalent type of germ cell tumors and usually display benign characteristics. Mature cystic teratomas consist of a varied mixture of mature tissue types that originate from squamous epithelium and skin adnexal structures. It is most commonly found in female gonads.

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Article Synopsis
  • * It involved 933 patients aged 60 and above, and highlighted significant associations between age, body mass index (BMI), ASA classification, and cognitive function, as well as the impact of these factors on QOL post-surgery.
  • * Key findings suggest that understanding these preoperative factors can help in predicting cognitive changes and QOL, informing better preoperative planning for elderly patients.
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  • The study investigates how consistent Indonesian pathologists are in diagnosing thyroid tumors, focusing on identifying nuclear features and invasion characteristics of the tumors.* -
  • Fifteen pathologists independently ranked 14 digital slides, revealing that initial agreement on key features was low, but training improved these scores significantly.* -
  • The findings highlight the need for continued education and collaboration among pathologists to enhance diagnostic accuracy in thyroid neoplasms.*
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  • Active venous leg ulcers (VLU) are a serious form of chronic venous disease that drastically impact patients' health and quality of life, prompting economic concerns due to the need for treatment.* ! -
  • The study describes three patients with active VLUs treated through endovenous laser ablation (EVLA), which involved using specific laser energy protocols to target severe great saphenous vein reflux.
  • Follow-up results showed significant healing of the ulcers and reduced venous clinical severity scores, indicating that EVLA is a safe and effective treatment for patients with VLUs.
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Introduction And Importance: Type 1 jejunoileal atresia with multiple webs is a rare congenital condition that poses significant surgical challenges in neonates. Understanding the unique presentation and management strategies in such cases is crucial for improving patient outcomes.

Case Presentation: We report two cases involving full-term neonates presenting with severe abdominal distension and bilious vomiting.

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The increasing incidence of chronic conditions on a global scale requires a comprehensive approach to palliative care, which is recognized as an essential element of the continuum of care for people with life-threatening conditions. It has been argued that the integration of early palliative care for people with chronic conditions is beneficial. Nevertheless, barriers to integrating early palliative care have been extensively not reviewed.

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Purpose: Non-puerperal uterine inversion (NPUI) is a rare gynaecological entity with unknown actual incidence. It presents diagnostic and surgical challenges, due to its rarity and lack of clinical experience.

Methods: Case series of 5 NPUI cases.

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Dermatofibrosarcoma Protuberans in a 12-Year-Old Child: A Rare Case.

Clin Cosmet Investig Dermatol

August 2024

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.

Article Synopsis
  • Dermatofibrosarcoma protuberans (DFSP) is a rare skin tumor that typically appears as a firm, slowly growing plaque, mostly found in the trunk area and is uncommon in children.
  • A 12-year-old girl showed symptoms of DFSP with a painless dark patch on her nose after radiotherapy; she underwent wide local excision resulting in the removal of the tumor.
  • Histopathological examination confirmed the diagnosis as stage II DFSP, and treatment included 25 sessions of radiotherapy, with no recurrence observed after subsequent surgeries.
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Purpose: The duration for which anterior cruciate ligament reconstruction (ACLR) can be delayed without resulting in a risk of subsequent meniscus injury has remained a debatable topic. The main purpose of this study was to determine the safest delay interval for a delayed ACLR.

Methods: This retrospective study included all patients who underwent ACLR between January 2020 and January 2022.

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Article Synopsis
  • - Familial Reactive Perforating Collagenosis (FRPC) is a rare, benign skin condition primarily seen in young children, with fewer than 50 documented cases, and its causes and treatments remain unclear.
  • - A case study of a 20-year-old male from Indonesia showed multiple skin papules across his body for over 7 years, and similar symptoms were present in his family.
  • - The patient was successfully treated with a topical corticosteroid, desoximetasone, leading to significant improvement in skin lesions, suggesting corticosteroids could be a viable treatment for FRPC.
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Left main (LM) percutaneous coronary intervention (PCI) has expanded rapidly in the past decade, with up to fourfold increase annually. Recent trials found that intravascular imaging (IVI)-guided LM PCI resulted in lower risks of cardiac death and stent failure due to suboptimal PCI compared to angiography-guided PCI. IVI usage has increased in recent years; however, its utilization remains variable across regions and is still incredibly low in developing countries.

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Purpose: This study aimed to investigate the clinicopathological characteristics of oral squamous cell carcinoma (OSCC) patients and analyze the relationship between the degree of differentiation and factors including age, sex, stage, and tumor location in West Java, Indonesia.

Patients And Methods: A retrospective cross-sectional study was conducted at the Central Referral and Teaching Hospital in West Java, Indonesia. The data were collected by reviewing medical records with International Classification of Diseases (ICD) codes C00-C06 from 2016 to 2023.

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 Urinary tract infection (UTI) is one of the commonly encountered conditions in children. Dimercaptosuccinic acid (DMSA) scintigraphy is widely advocated for functional and morphological evaluation of the renal cortex including parenchymal defect. Moreover, only a small percentage of renal defects are detected by ultrasound.

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Background: High intracranial pressure (ICP) is one of the most common complications of central nervous system (CNS) infection. Failure to control high intracranial pressure results in brain herniation and death. One of the treatments for high ICP involves the administration of osmotherapy in the form of 3% NaCl or 20% mannitol with observation during administration.

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Article Synopsis
  • Thyrotoxicosis is linked to cardiovascular issues and may lead to conditions like tricuspid regurgitation (TR) and mitral regurgitation (MR), though research on these specific heart problems is still limited.
  • A systematic review analyzed 57 case reports of 62 predominantly female patients (average age 45.77 years) with thyrotoxicosis, revealing improvements in heart conditions like TR, MR, heart failure (HF), and pulmonary hypertension (PH) after treatment.
  • The study concludes that treating hyperthyroidism can lead to significant clinical recovery in heart issues within six months, driven by both direct effects of thyroid hormones and other related factors.
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Objective: Acute laceration wound (ALW) is one of the most common injuries in Indonesia with potential significant morbidities. In rural areas, povidone-iodine and honey are commonly used as wound dressings. This study aimed to identify the effectiveness of honey compared to paraffin gauze and the commonly used povidone-iodine in improving ALW healing time.

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Background: No specific data have been systematically collected regarding lymphoma patient characteristics, while non-Hodgkin lymphoma (NHL) is identified as the 7 most common cancer and Hodgkin lymphoma (HL) is the 28. Inflammation plays an important role in the pathogenesis and progression of lymphoma. Malnutrition is an adverse prognostic factor in lymphoma.

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Article Synopsis
  • Volar distal radioulnar joint (DRUJ) dislocation with an isolated ulnar styloid fracture is rare and often misdiagnosed, leading to delayed treatment and potential loss of function.
  • A 51-year-old woman was treated for a neglected volar DRUJ dislocation and ulnar styloid fracture after an initial misdiagnosis as a wrist sprain; surgery involved open reduction and stabilization techniques.
  • The report emphasizes the importance of evaluating the triangular fibrocartilage complex during surgery for long-term stabilization, suggesting that radioulnar K-wire stabilization along with tissue repair can lead to positive clinical results.
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Background: Malnutrition inflammation score (MIS) is an instrument for assessing the nutritional status of stage 5 CKD patients, while simplified creatinine index (SCI) is used to assess muscle mass indirectly.

Purpose: This study aims to analyse the correlation between SCI and MIS, as well as determine the SCI cut-off value as a predictor of malnutrition in stage 5 CKD patients on maintenance HD.

Methods: This research was an analytical observational study with a cross-sectional study approach.

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Introduction: Corona Virus Disease-19 (COVID-19) is a disease caused by Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2). The most reliable and widely accepted method for diagnosing this infection, despite facing various challenges, is the Reverse Transcription Polymerase Chain Reaction (RT-PCR) method, which utilizes nasopharyngeal swab sample. Reverse-transcription loop mediated isothermal amplification (RT-LAMP) is a simpler nucleic acid amplification method compared to the RT-PCR method.

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Introduction: Beta-thalassemia major is a blood disorder caused by impaired synthesis of hemoglobin beta chain. Oral manifestations of beta-thalassemia major in pregnancy have rarely been reported.

Objective: This study aimed to describe a case of oral manifestations in a pregnant woman with beta-thalassemia major for multidisciplinary management.

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Studies on head and neck cancer (HNC) patients undergoing radiotherapy have revealed increased numbers of spp., leading to oral candidiasis and oral mucositis. The effects of laser therapy on spp.

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Influence of bite force and implant elastic modulus on mandibular reconstruction with particulate-cancellous bone marrow grafts healing: An in silico investigation.

J Mech Behav Biomed Mater

September 2024

Oral and Maxillofacial Medical Staff Group, Hasan Sadikin General Hospital, Jalan Pasteur 38, Bandung, 40161, West Java, Indonesia; Oral and Maxillofacial Department, Faculty of Dentistry, Universitas Padjajaran, Jalan Sekeloa Selatan 1, Bandung, 40132, West Java, Indonesia; Mechanical Engineering Graduate Program, Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung, 40132, West Java, Indonesia.

Article Synopsis
  • The study explores how different bite forces and implant elastic properties affect healing during mandibular reconstruction using particulate cancellous bone marrow (PCBM) grafts.
  • Using a finite element model of a Canis lupus mandible, the research simulates tissue differentiation over 12 weeks to determine factors like healing rate, implant stress distribution, and new bone properties.
  • Results showed faster healing with lower bite forces and larger implant elasticity, with titanium (Ti6Al4V) outperforming stainless steel in long-term stress shielding, providing insights for improved implant design and postoperative strategies.
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