Functional activities of human antibody induced by the capsular polysaccharide or polysaccharide-conjugate vaccines against Haemophilus influenzae type b.

To determine the in vitro and in vivo activity of human antibody induced by different Haemophilus influenzae type b (Hib) vaccines, pooled human antisera obtained from adults immunized with either polyribosyl ribitol phosphate (PRP) or PRP-conjugated with diphtheria toxoid (PRP-D) vaccines were evaluated for opsonic and protective activity against Hib. In vitro, opsonophagocytic studies revealed that PRP-D induced antisera were approximately 2.5-fold more effective than PRP-induced antisera in supporting neutrophil-mediated killing of an Hib strain.

Three day crisis resolution unit.

This paper describes a three day crisis resolution unit within the confines of the psychiatric emergency service of a general hospital. It utilizes a crisis model of acute intervention, time limited psychotherapeutic approach combined with family therapy, and psychotropic medications when indicated. 136 consecutive admissions were reviewed, 49% were discharged within 72 hours, and 51 % required further hospitalization.