5 results match your criteria: "Harbin Medical UniversityHarbin 150086[Affiliation]"
MiR-216a exerts tumor-suppressing functions in renal cell carcinoma by targeting TLR4.
Am J Cancer Res
March 2018
Department of Urology, The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150086, China.
Article Synopsis
- MiR-216a is a special tiny RNA that can help stop cancer, but its role in a type of kidney cancer called RCC is not well understood.
- In this study, researchers found that miR-216a levels were lower in RCC tissues and cells, and when they increased it, cancer cell growth and movement were reduced.
- The study shows that miR-216a works by targeting another protein called TLR4, suggesting miR-216a could be a new way to treat RCC.
Expression of long non-coding RNA HOXA11-AS is correlated with progression of laryngeal squamous cell carcinoma.
Am J Transl Res
February 2018
Department of Otorhinolaryngology, Head and Neck Surgery, The Second Affiliated Hospital, Harbin Medical UniversityHarbin 150086, China.
Long noncoding RNA HOXA11 antisense RNA (HOXA11-AS) is involved in tumorigenesis and development of some human cancers. However, the role of HOXA11-AS in human laryngeal squamous cell cancer (LSCC) is yet unclear. In this study, we firstly investigated the expression of HOXA11-AS in LSCC.
View Article and Find Full Text PDFDexmedetomidine alleviates LPS-induced septic cardiomyopathy via the cholinergic anti-inflammatory pathway in mice.
Am J Transl Res
November 2017
Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical UniversityHarbin 150001, China.
This study was conducted to investigate the role of the cholinergic anti-inflammatory pathway in LPS-induced septic cardiomyopathy in mice. C57BL/6 mice were used to construct septic cardiomyopathy models. The optimal duration of lipopolysaccharide (LPS) treatment was determined by HE staining and TUNEL assay.
View Article and Find Full Text PDFGTS-21 attenuates LPS-induced renal injury via the cholinergic anti-inflammatory pathway in mice.
Am J Transl Res
October 2017
Department of Critical Care Medicine, The Cancer Hospital of Harbin Medical UniversityHarbin 150081, China.
This study aimed to investigate the role of GTS-21 in cholinergic anti-inflammatory pathway-mediated protection of LPS-induced septic renal injury in mice. C57BL/6 mice were used to construct septic injury models. The optimal duration of lipopolysaccharide (LPS) treatment was determined using HE staining and TUNEL assay.
View Article and Find Full Text PDFLong nonding RNA UCA1 regulates neural stem cell differentiation by controlling miR-1/Hes1 expression.
Am J Transl Res
August 2017
Department of Neurosurgery, The First Hospital of Harbin Medical UniversityHarbin 150001, Heilong Jiang, China.
Neural stem cells are able to self-renew and generate glial and neuronal lineages. Neural stem cell may serve as therapeutic method for neurological disorders including spinal cord injuries, Parkinson's disease, Huntington's disease and Alzheimer's disease. Long noncoding RNAs (lncRNAs) are longer than 200 nucleotides with limited protein-coding capacity.
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