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Influenza virus infection is a serious problem in the elderly because of the high pneumonia complication rate and a significant increase in mortality. Influenza vaccine is a method for controlling influenza epidemics in the elderly. The vaccinated elderly showed lower influenza infection rate and had fewer incidences of febrile episodes than did non-vaccinees during epidemics.

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T cell vaccination, originally contrived and coinned by I.R. Cohen is the injection of autoimmune pathogenic T cell line/clone or T cell receptor peptides in an attempt to induce anti-idiotypic regulation to treat autoimmune disease.

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