2 results match your criteria: "Hannover Medical School and Center for Systems Neuroscience (ZSN)[Affiliation]"
In vitro models for peripheral nerve regeneration.
Eur J Neurosci
February 2016
Institute of Neuroanatomy, Hannover Medical School and Center for Systems Neuroscience (ZSN), Hannover, Germany.
The study of peripheral nerve repair and regeneration is particularly relevant in the light of the high clinical incidence of nerve lesions. However, the clinical outcome after nerve lesions is often far from satisfactory and the functional recovery is almost never complete. Therefore, a number of therapeutic approaches are being investigated, ranging from local delivery of trophic factors and other molecules to bioactive biomaterials and complex nerve prostheses.
View Article and Find Full Text PDFSchwann cells overexpressing FGF-2 alone or combined with manual stimulation do not promote functional recovery after facial nerve injury.
J Biomed Biotechnol
December 2009
Institute of Neuroanatomy, Hannover Medical School and Center for Systems Neuroscience (ZSN), Hannover, Germany.
Purpose: To determine whether transplantation of Schwann cells (SCs) overexpressing different isoforms of fibroblast growth factor 2 (FGF-2) combined with manual stimulation (MS) of vibrissal muscles improves recovery after facial nerve transection in adult rat.
Procedures: Transected facial nerves were entubulated with collagen alone or collagen plus naïve SCs or transfected SCs. Half of the rats received daily MS.