93 results match your criteria: "Hamadan University of Medical Sciences. Hamadan[Affiliation]"

Background And Aims: The patellar tendon-bearing (PTB) brace is a crucial device designed to lessen axial forces on the tibia. The newly designed PTB brace allows clinicians to measure offloading amount in the realtime. This study aimed to explore the relationship between a rise in displacement between the foot plate and calf shells of this new PTB brace and changes in the amount of offloading on the tibia.

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Selective reduction of bilateral nonsyndromic talon cusps in an 11-year-old class II patient enabled successful mandibular repositioning with a twin block appliance. This approach achieved desired orthodontic outcomes without causing pain or sensitivity following reduction, highlighting a novel strategy for managing talon cusps in orthodontic treatment.

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Nonmelanoma skin cancer (NMSC) represents the most prevalent form of skin cancer globally, with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) being the most common types. The search for effective chemopreventive and therapeutic agents has led to the exploration of natural compounds, among which resveratrol (RES), a polyphenolic phytoalexin found in grapes, berries, peanuts, and red wine, has garnered significant attention. This comprehensive review aims to elucidate the effects of RES on NMSC, focusing on its mechanisms of action, efficacy in preclinical studies, and potential as a chemopreventive and therapeutic agent.

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This study investigated the effects of different doses of vitamin E on oxidative stress, cognitive function, and gene expression in aged mice. A total of 32 male mice, aged 12 months, were divided into a control group and three treatment groups. These groups received varying daily doses of vitamin E for a period of 28 days.

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  • This study examines heparin-induced thrombocytopenia (HIT-II), a serious complication in hospitalized patients receiving heparin, particularly after surgery or for deep vein thrombosis (DVT).
  • The research involved 754 patients and found a HIT-II incidence rate of 4.50%, with higher occurrences in older adults and females, along with increased thrombosis rates and elevated levels of various inflammatory markers.
  • The study concludes that platelet activation in HIT-II patients contributes to more thrombosis formation, longer hospital stays, and higher mortality rates compared to non-HIT patients.
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Key Clinical Message: Microvascular angina (MVA) can present with recurrent chest pain and normal coronary angiography. Recognizing MVA is crucial as it significantly impacts patient morbidity and mortality. Early diagnosis and management with antianginal medications are essential for improving outcomes and quality of life.

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Introduction: Reinfection with SARS-Cov-2 after recovery can occur that most of them don't require hospitalization. The aim of this study is estimation of out-patient COVID-19 reinfection and recurrence rates and its associated factors among Iranian patients with history of confirmed SARS-Cov-2 infection and hospitalization.

Methods: This study is a retrospective cohort conducted from May 2021 to May 2022 in Iran.

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Introduction: Reinfection and hospital readmission due to COVID-19 were significant and costly during the pandemic. This study aimed to assess the rate and risk factors of SARS-Cov-2 reinfection, recurrence, and hospital readmission, by analyzing the national data registry in Iran.

Methods: This study was a retrospective cohort conducted from March 2020 to May 2021.

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  • Cerebrovascular events, like strokes, are connected to cardiac issues, especially in patients with chronic inflammatory diseases.
  • Conditions like rheumatoid arthritis (RA) raise the risk of both cardiovascular problems and strokes.
  • This relationship emphasizes the complexity of these health issues and the importance of an integrated medical approach involving multiple specialties.
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  • Hepcidin plays a key role in regulating iron levels during inflammatory conditions like inflammatory bowel disease (IBD), prompting a systematic review and meta-analysis to explore its association with IBD.
  • The analysis included 10 studies with 1,184 participants, revealing that patients with IBD had significantly higher serum hepcidin levels compared to healthy controls, while prohepcidin levels were slightly lower but not significantly different.
  • Significant variability was found among the studies, especially for hepcidin levels, indicating that while hepcidin is elevated in IBD, the clinical importance of this increase is still unclear and requires more research.
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Introduction: Assessing vaccine willingness and understanding sources of vaccine hesitancy in individuals with multiple sclerosis (MS) helps healthcare providers approach patients more effectively while respecting their autonomy to encourage coronavirus disease 2019 (COVID-19) vaccination.

Materials And Methods: A descriptive-analytical cross-sectional study using a researcher-made checklist was conducted on MS patients referred to Neshat Clinic of Hamadan during the years 2020-2021. The checklist contained questions about demographic information, MS phenotype, duration of illness, expanded disability status scale (EDSS) score, and COVID-19 vaccination status.

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  • * The case report discusses a patient with a CHA2DS2-VASc score of 1, facing a controversial decision about starting anticoagulant therapy due to this condition.
  • * The authors suggest that Cor triatriatum should be viewed as an additional risk factor for anticoagulant therapy, but stress the need for more research and individualized treatment strategies in similar cases.
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Key Clinical Message: Adenoid cystic carcinoma (ACC) is an uncommon malignancy of head and neck. Although the cornerstone of treatment is surgery, concurrent chemoradiotherapy (CRT) might be used as an effective treatment for unresectable tumors. Herein we report a case of massive ACC of base of tongue with durable complete response to definitive CRT.

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Tissue regeneration is the procedure of renewal, restoration and growth of injured tissues and defective organs including nerve, bone, tooth, cartilage and blood vessels. Repair process of damaged tissues needs non-invasive methods; so, the scientists have recently focused on alternative treatment pathways. Nano gels based on Poly Lactic-co-Glycolic Acid have been designed for different purposes in medicine.

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The aim of this study was to develop a new method for sampling and analyzing polycyclic aromatic hydrocarbons in the air. This was achieved by utilizing a needle trap device packed with a modified porous aromatic framework coated with magnetic nanoparticles (PAF-6-MNPs). The modified adsorbent underwent qualitative evaluation using Fourier-transform infrared spectroscopy and X-ray diffraction, as well as scanning and transmission electron microscopy.

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Key Clinical Message: The key takeaway from this clinical scenario is to choose the most appropriate and reasonable treatment plan when dealing with a patient who has atrial septal defect (ASD) and concurrent atrial and mediastinal masses. In such cases, a heart-oncology team should make the therapeutic decision.

Abstract: Right atrial masses are not pretty rare and might be a diagnostic challenge.

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Orthodontic tooth movement (OTM) is a critical process in dental alignment, driven by the application of calibrated orthodontic forces. This study delves into the intricate molecular and cellular mechanisms by which vitamin D3 influences OTM. Vitamin D3 is identified as a critical regulator in bone metabolism, enhancing osteoblast activity and bone formation while also modulating osteoclast quantity and RANKL expression, essential for the remodeling of the alveolar bone.

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A nanoparticle-drug delivery system against , especially , has been recently proposed as an alternative pathway therapy. is resistance to many antibiotics, making it a a threat to human life, especially for older and immunocompromised people. Treatment of is considered an urgent need.

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In this study, gluten-free pancakes were prepared using rice flour and potato starch at a ratio of 50:50. Due to a lack of gluten networks in these ingredients, the hydrocolloid gums including carboxymethyl cellulose (CMC) at 0.5%, 1%, and 1.

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  • * Natural compounds like ellagic acid (EA) have gained attention for their potential antitumor properties and fewer side effects in BC therapy.
  • * EA affects BC cells by inhibiting growth, migration, and angiogenesis, while promoting apoptosis and impacting critical signaling pathways, though more research is needed to clarify its clinical applications.
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Non-alcoholic fatty liver disease (NAFLD) is frequently linked to metabolic disorders and is prevalent in obese and diabetic patients. The pathophysiology of NAFLD involves multiple factors, including insulin resistance (IR), oxidative stress (OS), inflammation, and genetic predisposition. Recently, there has been an emphasis on the use of herbal remedies with many people around the world resorting to phytonutrients or nutraceuticals for treatment of numerous health challenges in various national healthcare settings.

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Introduction: Cardiac arrhythmias, including ventricular tachycardia (VT), stand as a significant threat to health, often leading to mortality and sudden cardiac death. While conventional treatments for VT exhibit efficacy, cases of refractory VT pose challenges. Stereotactic Arrhythmia Radioablation (STAR) offers a novel approach, delivering precise high-dose radiation to well-defined targets with minimal collateral damage.

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The anticancer properties of curcumin have been broadly examined in several shapes, such as nanoparticles and nanocomposite structures. Despite its benefits, curcumin also has some disadvantages, including rapid metabolism, poor absorption, and rapid systemic excretion. Therefore, numerous strategies have been used to increase curcumin's bioavailability.

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