1,259 results match your criteria: "Hair Graft Transplantation for Baldness"

Background And Rationale: Scarring alopecia significantly impacts patients' appearance and psychological well-being. Surgery is a common cause of scarring alopecia, making positive treatment crucial for patients' overall health.

Objective: To investigate the clinical efficacy of autologous follicular unit extraction (FUE) transplantation for postoperative secondary stable scarring alopecia and evaluate its effectiveness.

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Background: Hair transplantation (HT) has been reported to be effective for the treatment of female-pattern hair loss (FPHL). Few studies have investigated HT in FPHL.

Objective: To evaluate the clinical features of FPHL treated with HT and analyze the real-world results of HT.

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Plastic surgeons face unique challenges in reconstructing eyebrows due to their complex anatomy and gender variations. We report a case of a 16-year-old female who presented with post-burn bilateral eyebrow alopecia. Bilateral eyebrow reconstruction was performed with scalp island flaps based on the posterior branch of the superficial temporal artery, which showed good postoperative outcomes.

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Restoration of follicular β-catenin signaling by mesenchymal stem cells promotes hair growth in mice with androgenetic alopecia.

Stem Cell Res Ther

November 2024

State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.

Background: The use of mesenchymal stem cells (MSCs) is recognized as a promising strategy for the treatment of androgenetic alopecia (AGA). However, the underlying mechanism remains to be explored. Here, we evaluated the therapeutic effects and potential mechanisms of the use of human umbilical cord mesenchymal stem cells (hUCMSCs) in dihydrotestosterone (DHT)-induced AGA models in vivo and in vitro.

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A Prospective and Comparative Study to Explore the Effects of Platelet-Rich Plasma in Hair Transplantation for Patients With Androgenetic Alopecia.

J Cosmet Dermatol

November 2024

Department of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.

Background: Androgenetic alopecia (AGA) is the most prevalent type of hair loss. Traditionally, treatment for AGA has primarily involved the topical application of minoxidil in conjunction with oral finasteride or spironolactone. Recently, platelet-rich plasma (PRP) has emerged as a significant focus of research in hair loss treatment.

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Article Synopsis
  • Hair follicles undergo a continuous cycle of growth (anagen), regression (catagen), and rest (telogen), with the time spent in each phase affecting hair length and health.
  • Traditional beliefs suggest that 85%-90% of hair follicles are in the growth phase, but recent studies indicate that these values may not be accurate due to flaws in assessment methods.
  • A new examination of hair follicles during hair transplants revealed that catagen follicles (7.5%) are more prevalent than previously thought, challenging the established belief about the distribution of hair follicles in different stages.
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Impact of Finasteride and Dutasteride in Beard Thickness in Men With Androgenetic Alopecia: A 453-patient Retrospective Trial.

Actas Dermosifiliogr

October 2024

Dermatology Department, Trichology Unit, Ramon y Cajal University Hospital, University of Alcala, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, España; Trichology and Hair Transplantation Unit, Grupo Pedro Jaen Clinic, Madrid, España.

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Background: The robotic hair transplant technology, ARTAS, has a series of fine mechanical structure and an intelligent recognition system that allows it to independently select hair follicular units (FUs) and effectively harvest hair. After entering China in 2016, ARTAS has attracted the attention of hair transplant surgeons and hair loss patients given its advantages in a short learning curve and simple operation.

Objective: To compare the efficacy and safety between the ARTAS system and follicular unit excision (FUE) in the treatment of male androgenetic alopecia (AGA) and to further promote the improvement and upgrading of ARTAS technology concerning hair transplantation.

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LncRNA NEAT1 and miRNA 101 as potential diagnostic biomarkers in patients with alopecia areata.

Noncoding RNA Res

February 2025

Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Fayoum University, Fayoum, 63514, Egypt.

Article Synopsis
  • Alopecia areata (AA) is a condition that causes patchy hair loss and is linked to immune system problems and genetics.
  • The study looked at specific molecules in the blood, NEAT1 and miR-101, to see if they could help diagnose the disease.
  • Results showed that miR-101 could be used as a helpful tool to diagnose AA, with some interesting numbers about how accurate it is.
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Article Synopsis
  • Follicular unit hair extraction (FUE) is commonly used for hair restoration but struggles with scarred tissue, and stem cell therapy may enhance its effectiveness.
  • In a study with 60 patients, those who received stem cell therapy before FUE (Group A) had significantly better hair density and graft survival rates compared to those who did not (Group B).
  • Histological analyses indicated that Group A experienced improved tissue regeneration with more blood vessels and less scar tissue, leading to higher patient satisfaction scores.
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Self-management in the post-hair transplantation recovery period among patients with androgenetic alopecia: A qualitative study.

Int J Nurs Stud Adv

December 2024

Department of Plastic Surgery, The First People's Hospital, 310000, Address :No.261, Huansha Road, Hangzhou, Zhejiang, China.

Article Synopsis
  • * A study was conducted with patients who underwent this surgery, focusing on their self-management challenges and resources, through one-on-one interviews.
  • * Key findings showed patients struggled with medication, wound care, and emotional well-being, highlighting the need for support programs to improve recovery and overall results.
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Mesenchymal Stem Cell Therapy in Alopecia Areata: Visual and Molecular Evidence from a Mouse Model.

Int J Mol Sci

August 2024

Department of Dermatology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea.

Article Synopsis
  • Recent studies suggest that Mesenchymal Stem Cells (MSCs) could be a promising treatment for Alopecia Areata (AA) due to their ability to suppress the immune response.
  • In animal experiments, MSC therapy showed improved hair regrowth and reduced local inflammatory cytokines in mice with AA compared to a control group.
  • The treatment also normalized important signaling pathway genes and growth factors involved in hair cycle regulation, indicating the need for further research on MSCs' effectiveness for AA treatment.
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Article Synopsis
  • The ALLEGRO study showed that ritlecitinib, a JAK3/TEC inhibitor, is effective and safe for treating alopecia areata in patients aged 12 and older with significant scalp hair loss.
  • A post hoc analysis examined how previous alopecia treatments affected treatment outcomes using the Severity of Alopecia Tool (SALT) in patients taking ritlecitinib.
  • Results indicated that prior use of intralesional corticosteroids improved short-term outcomes, while systemic immunosuppressants worsened them, but overall, previous treatment history did not significantly influence long-term responses to ritlecitinib.
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Background: Alopecia areata is an autoimmune condition characterized by rapid hair loss in the scalp, eyebrows and eyelashes, for which treatments are limited. Baricitinib, an oral inhibitor of Janus kinases 1 and 2, has been recently approved to treat alopecia areata.

Materials And Methods: We conducted a retrospective study involving 23 medical centres across Italy, enrolling patients affected by severe alopecia areata (SALT >50), for more than 6 months.

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A Scoping Review on Complications in Modern Hair Transplantation: More than Just Splitting Hairs.

Aesthetic Plast Surg

August 2024

Department of Otolaryngology-Head and Neck Surgery, Division of Facial Plastic and Reconstructive Surgery, Harvard Medical School, Massachusetts Eye and Ear, 243 Charles Street, Boston, MA, 02114, USA.

Article Synopsis
  • Hair restoration surgery (HRS) is popular but lacks comprehensive reviews of its complications, prompting a study aimed at detailing issues linked to follicular unit extraction (FUE) and follicular unit transplantation (FUT).
  • A review of 43 publications found overall complication rates between 1.2% and 4.7%, with common issues including bleeding, persistent numbness, and infections, as well as donor site complications like scarring and a range of recipient site problems.
  • While serious complications are rare among skilled practitioners, it's crucial for surgeons to discuss potential risks with patients, as even minor issues can have significant psychological impacts.
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Recipient Site Necrosis After Follicular Unit Excision Technique For Hair Transplantation: Evaluation of 18 Patients.

Aesthetic Plast Surg

October 2024

Department of Plastic, Reconstructive and Aesthetic Surgery, Biruni University Medical Faculty, Istanbul, Turkey.

Article Synopsis
  • Hair transplantation is generally safe but can lead to complications like recipient site necrosis (RSN), a rare yet serious issue; this study analyzes 18 patients who experienced RSN after the procedure from 2017 to 2023.* -
  • The research involved reviewing patient records and found that most patients were around 36 years old, with common risk factors including smoking (66.7%), hypertension (20%), and diabetes (13.3%); all patients underwent single-session follicular unit excisions.* -
  • The study highlights the importance of recognizing and managing risk factors to prevent RSN, emphasizes early treatment for better outcomes, and indicates that while many cases can be managed conservatively, some may require surgical intervention
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The condition of hair follicles produced by different punching methods during FUE surgery.

J Cosmet Dermatol

December 2024

Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.

Article Synopsis
  • This study examines the effectiveness of two methods, rotary and oscillatory, for extracting hair grafts in follicular unit extraction (FUE) surgery using a sample of 15 patients.
  • The results showed that while both methods yielded a similar average number of hairs per graft, the oscillatory method had a significantly higher total yield rate, especially in cases with soft scalps or deeper punch requirements.
  • The research suggests that the oscillatory punch method is preferable in certain conditions, and emphasizes the importance of structured guidelines to enhance graft quality and minimize complications.
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Serial Excision Technique to Reduce Cicatricial Alopecia.

Skin Appendage Disord

August 2024

Department of Dermatologic Surgery, Dermatology Institute Prof. Rubem David Azulay (IDPRDA), Santa Casa da Misericórdia, Rio de Janeiro, Brazil.

Introduction: Cicatricial alopecia (CA) poses a challenge for dermatologists due to irreversible hair follicle damage. While pharmacological treatments offer limited efficacy, surgical interventions aim to improve aesthetic outcomes. This article explores the serial excision technique (SET) as a viable option for stable cases of inflammatory CA.

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Current Protocols: Alopecia Areata Mouse Models for Drug Efficacy and Mechanism Studies.

Curr Protoc

August 2024

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.

Alopecia areata is the second most common form of hair loss in humans after androgenetic alopecia. Although a variety of animal models for alopecia areata have been described, currently the C3H/HeJ mouse model is the most commonly used and accepted. Spontaneous hair loss occurs in 15%-25% of older mice in which the lesions wax and wane, similar to the human disease, with alopecia being more common and severe in female mice.

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Article Synopsis
  • Hair transplantation, specifically using follicular unit extraction (FUE), can result in complications like pain and numbness due to slow healing at donor sites, highlighting the need for better post-operative care.
  • This study examined the effectiveness of hair follicular-derived microtissue (HFMT) in enhancing wound healing and reducing complications compared to other treatments like mupirocin and no treatment at all.
  • Results showed that donor sites treated with HFMT healed faster and had lower pain and itching levels compared to other methods, indicating that HFMT may be a promising solution for improving recovery after FUE hair transplants.
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[Reconstruction of eyebrows by follicular transplantation].

Ann Chir Plast Esthet

November 2024

Centre médico-chirurgical du cuir chevelu, 23, avenue Niel, 75017 Paris, France. Electronic address:

The eyebrow is an aesthetic unit playing an important role in the balance and expression of the face. It consists of hairs whose different orientations make its complexity. The main causes of eyebrow alopecia are repeated eyebrow plucking, reduced density due to age, and post-traumatic alopecia.

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Application of Non-Pharmacologic Therapy in Hair Loss Treatment and Hair Regrowth.

Clin Cosmet Investig Dermatol

July 2024

Department of Dermatology, Venereology and Cosmetology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.

Purpose: Alopecia significantly affects the appearance and psychology of patients, and pharmacological therapies and hair transplantation are the main treatments for alopecia, but both have limitations. This review aimed to summarize the non-pharmacological therapies that promote hair growth and regeneration.

Patients And Methods: This is a non-systematic review.

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Oral dutasteride is a first-line treatment for frontal fibrosing alopecia.

J Eur Acad Dermatol Venereol

August 2024

Hair Disorders Unit, Dermatology Department, Ramon y Cajal Hospital, IRYCIS, University of Alcala, Madrid, Spain.

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Impact of Finasteride and Dutasteride in Beard Thickness in Men With Androgenetic Alopecia: A 453-patient Retrospective Trial.

Actas Dermosifiliogr

July 2024

Dermatology Department, Trichology Unit, Ramon y Cajal University Hospital, University of Alcala, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain; Trichology and Hair Transplantation Unit, Grupo Pedro Jaen Clinic, Madrid, Spain.

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