3 results match your criteria: "Hainan University Haikou 570228 China chentieqiao@hnu.edu.cn.[Affiliation]"
Site-selective decarbonylative [4 + 2] annulation of carboxylic acids with terminal alkynes by C-C/C-H activation strategy and cluster catalysis.
Chem Sci
December 2024
School of Chemistry and Chemical Engineering, Hainan University Haikou 570228 China
Article Synopsis
- The manuscript presents a novel palladium-catalyzed cyclization method using carboxylic acids and terminal alkynes, which showcases its potential for creating complex organic molecules.
- This technique is significant as it allows carboxylic acids, traditionally underutilized, to serve as effective building blocks in intramolecular cycloaddition and addresses long-standing challenges in synthesizing substituted naphthalenes.
- The reaction demonstrates a wide range of substrate compatibility and functional group tolerance, making it applicable for scalable synthesis in organic chemistry, drug discovery, and material science.
Metal-free highly chemo-selective bisphosphorylation and deoxyphosphorylation of carboxylic acids.
Chem Sci
May 2023
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Hainan Provincial Key Lab of Fine Chem, Hainan Provincial Fine Chemical Engineering Research Center, Hainan University Haikou 570228 China
Carboxylic acids are readily available in both the natural and synthetic world. Their direct utilization for preparing organophosphorus compounds would greatly benefit the development of organophosphorus chemistry. In this manuscript, we describe a novel and practical phosphorylating reaction under transition metal-free reaction conditions that can selectively convert carboxylic acids into the P-C-O-P motif-containing compounds through bisphosphorylation, and the benzyl phosphorus compounds through deoxyphosphorylation.
View Article and Find Full Text PDFDirect phosphorylation of benzylic C-H bonds under transition metal-free conditions forming spC-P bonds.
RSC Adv
June 2022
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Hainan Provincial Key Lab of Fine Chem, Hainan Provincial Fine Chemical Engineering Research Center, Hainan University Haikou 570228 China
Direct phosphorylation of benzylic C-H bonds was achieved in a biphasic system under transition metal-free conditions. A selective radical/radical spC-H/P(O)-H cross coupling was proposed, and various substituted toluenes were applicable. The transformation provided a promising method for constructing spC-P bonds.
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