Water, electrolyte, and endocrine homeostasis in infants with bronchiolitis.

Twenty-two of 23 consecutive infants with bronchiolitis, 5.5 +/- 3.5 mo of age, showed a 1.

Early spontaneous rupture of the post myomectomy gravid uterus.

Rupture of a pregnant uterus is a serious threat to the mother's life and her fetus. Most of these cases have predisposing factors of which a post myomectomy scar is rare. Rupture of a post myomectomy gravid uterus usually occurs in the third trimester of pregnancy or during labor.

Doppler assessment of the effects of isometric stress on left ventricular filling in hypertensive young adults.

Doppler interrogation at the in-flow of the left ventricle was used to test the effects of isometric stress on ventricular filling in 7 hypertensive subjects with mild to moderate left ventricular hypertrophy, aged forty-two +/- seven years, compared with 9 matched healthy control males. In the hypertensive patients at rest, peak early diastolic (E) velocity was lower, and atrial (A) velocity higher, with lower E/A peak velocity ratios than in normals (p less than 0.05).

Fracture of the femur after total hip arthroplasty.

The classification and treatment of ipsilateral femur fractures after total hip arthroplasty are described on the basis of the predicted stability of the implant after the fracture. Conservative treatment was successful in most cases.

Burn resuscitation with a low-volume plasma regimen--analysis of mortality.

The results of a mortality analysis from the Burn Center in Rambam Medical Center, Haifa, Israel, over a 5-year period are presented. The management of severe burns during the 'shock' period included a low-volume resuscitation formula consisting mainly of plasma and a small volume of crystalloid solution. The efficacy of burn management was assessed by probit analysis of the mortality data.

Radiation carcinogenesis in the male breast.

A 53-year-old man developed cystic papillary carcinoma of the breast 30 years after radiotherapy to his chest. This rare type of carcinoma has not been previously reported following irradiation. In contrast to the comprehensive literature on irradiation as an etiological factor in carcinogenesis of the female breast, only 10 cases have been reported in males.

Colitis and pericarditis in a patient with eosinophilic fasciitis. A contribution to the multisystem nature of eosinophilic fasciitis.

A case of eosinophilic fasciitis (EF), associated with monoclonal gammopathy, thyroglobulin antibodies, pericarditis and colitis, is described. The occurrence of EF in the framework of a multisystem disease is the outstanding feature, contrasting with the absence of visceral involvement or solitary organ involvement in the large majority of cases. The unusual histologic features of the colitis and beneficial effect of cimetidine on EF are discussed.

Clinical significance of paraneoplastic syndrome.

The prevalence, clinical presentations, and diagnostic significance of the paraneoplastic syndrome (PNS) in the setting of a department of internal medicine in a community hospital was studied. During a 7-year period (1979-1985) a total of 167 patients among 11,000 hospitalized patients were diagnosed as having a malignant neoplasia previously unknown. From this group we selected all cases who presented with one or more of the known clinical PNSs.

Incidence and diagnostic significance of paraneoplastic thromboembolism disorders. A survey from a community hospital.

The incidence of paraneoplastic thromboembolic disorders (PTD) at first presentation of cancer and its diagnostic significance as a cancer marker are unknown. Fourteen thousand two hundred and eighty-seven patients were admitted to the department of medicine during the period 1978-1987. Nine amongst those patients had thromboembolic disorders (TE) as the initial clinical disturbance.

Ototoxicity of ear drops in patients suffering from chronic otitis media.

The sensorineural hearing loss in 150 patients with chronic otitis media who were treated in the Haifa Medical Center (Rothschild) during a ten year period was studied. There were 124 patients treated with a mixture containing neomycin, polymyxin B and dexamethasone and a control group of 26 patients with dexamethasone only. All patients were followed up for a period of 1-2 years.

Maturation of composite ligament.

A variety of synthetic fibrillar ligaments are being developed and clinically investigated. The tissue response to the variety of polymeric fibrils is similar. The soft-tissue response to carbon fiber braid substituting for lateral collateral ligament in three human knees and for the anterior cruciate ligament in one was examined 12-42 months after surgery.

Liposarcoma of the larynx.

Liposarcomas of the larynx are very rare. Only nine cases appear to have been recorded in the English literature. An additional case of liposarcoma of the larynx occurring in a young patient is reported and the relevant literature discussed.

Histoplasmosis of kidneys presenting as chronic recurrent renal disease.

Histoplasmosis is a well-known infectious disease that can sometimes run a mysterious and unexpected course. A case is reported that presented as a chronic renal process, with right pyelocutaneous fistula and prolonged purulent discharge as well as focal calcifications of the left kidney with recurrent stone formation. Histopathologic examination of the right kidney, removed in 1975, showed noncaseating granulomas, but the precise diagnosis was not made until 1983, when histopathologic re-examination followed partial resection of the left kidney, for recurrent stone formation.

A composite hip implant.

Composites are made of two or more different components that combine their properties into a new material. By modifying the type or structure or volume of the components, a theoretically endless number of new materials can be produced and their properties can be altered as desired. A composite hip implant made of carbon fiber and polysulfone is described.

Decrease in pulsatile flow in the internal carotid artery in fetal hydrocephalus.

The effect of ventriculomegaly on pulsatile flow in the internal carotid arteries has been studied by Doppler ultrasound in four hydrocephalic fetuses. The pulsatility index showed progressive elevation proportional to the developing ventriculomegaly and thus may be a valuable index for the study of the mechanism of brain injury and for the determination of optimal timing of intervention.

Corticosteroids in the management of sinoatrial block.

This report presented our experience in the treatment of sinoatrial (S-A) conduction disturbances with corticosteroids. Three patients with intermittent second-degree S-A block who failed to respond to atropine and isoproterenol were treated with prednisone for 6-17 weeks. Sustained improvement in S-A conduction following prednisone administration was confirmed by repeated Holter monitoring on and off therapy.

Intertrochanteric fracture of the hip. Comparison of nail-plate fixation and Ender's nailing.

Between April 1979 and August 1983, 201 patients with intertrochanteric fractures of the hip were admitted to Haife Medical Center (Rothschild), Israel. These patients were randomely divided into two groups: 104 patients underwent fixation with a compression screw and plate (Richard's Co.) and 97 patients underwent fixation with Ender's nails.

Familial recurrent dislocation of patella with autosomal dominant mode of inheritance.

Recurrent dislocation of the patella is considered to be a manifestation of generalized joint laxity. An autosomal dominant mode of inheritance was previously suggested in a few instances; however, male-to-male transmission has not yet been reported. We report a recurrent dislocation of the patella occurring in five generations of one family with male-to-male transmission and without generalized joint laxity.

Intermittent claudication: predictors and outcome.

The authors reviewed 460 patients with intermittent claudication. With primarily conservative management, these patients were followed for an average of 4.1 years (one to ten years).

Fetal arrhythmia associated with sinus node dysfunction--a case report.

Real time and M-mode echocardiography were used for evaluation of fetal bradycardia. Sinus bradycardia was revealed without structural abnormalities. An abdominal wall derived fetal electrocardiogram and the failure of the sinus rate to increase in response to maternal exercise or I.

Fetal internal carotid artery flow velocity time waveforms in twin pregnancies.

The fetal internal carotid artery and umbilical artery flow velocity time waveforms were studied in 17 consecutive twin pregnancies. The pulsatility index was calculated for each fetus in each artery as an index of vascular resistance. All studies were done within 14 days before delivery.

Post-obstructive urinary concentrating defect. A case study in the role of prostaglandins.

A child with post-obstructive urinary concentrating defect was studied for the possible pathophysiological role of prostaglandins and an eventual therapeutic approach. Increased urinary excretion of prostaglandins was corrected by indomethacin, with resultant increased nephrogenous cyclic AMP and partial improvement in the concentrating defect. The addition of a thiazide restored urinary concentration.

The clinical significance of multiple hair whorls and their association with unusual dermatoglyphics and dysmorphic features in mentally retarded Israeli children.

The prevalence of multiple hair whorls in a group of mentally retarded patients was 8% as opposed to 3.6% in a group of healthy children. A statistically significant relationship was demonstrated between mental retardation, multiple hair whorls, more than two dysmorphic features, and unusual dermatoglyphics.