Passive Expiration From Total Lung Capacity Can Estimate Expiratory Function in Infants A Retrospective Study.

Background: Evaluating expiratory airway function in infants is challenging because the criterion standard, the raised-volume rapid thoracoabdominal compression technique, is technically difficult and has a high failure rate.

Research Question: Are measurements obtained during passive expiration from total lung capacity correlated with forced expiration measurements obtained by the raised-volume technique in infants?

Study Design And Methods: This observational retrospective analysis included infants born ≥ 36 weeks' gestation who underwent pulmonary function testing using the raised-volume rapid thoracoabdominal compression technique at Hadassah Medical Centre between January 2011 and December 2019. Technically acceptable forced and passive flow-volume curve measurements were included in the analysis.

Paper waste and carbon emissions from oral contraceptive leaflets.

Oral contraceptives (OC) are the most used form of contraception among women in the U.S. and Europe.

Endovascular therapy in patients with acute intracranial non-terminal internal carotid artery occlusion (ICA-I).

Background: Acute intracranial occlusion of the internal carotid artery (ICA) can be distinguished into (a) occlusion of the terminal ICA, involving the proximal segments of the middle or anterior cerebral artery (ICA-L/-T) and (b) non-terminal intracranial occlusions of the ICA with patent circle of Willis (ICA-I). While patients with ICA-L/-T occlusion were included in all randomized controlled trials on endovascular therapy (EVT) in anterior large vessel occlusion, data on EVT in ICA-I occlusion is scarce. We thus aimed to evaluate effectiveness and safety of EVT in ICA-I occlusions in comparison to ICA-L/-T occlusions.

Modeling epithelial-mesenchymal transition in patient-derived breast cancer organoids.

Cellular plasticity is enhanced by dedifferentiation processes such as epithelial-mesenchymal transition (EMT). The dynamic and transient nature of EMT-like processes challenges the investigation of cell plasticity in patient-derived breast cancer models. Here, we utilized patient-derived organoids (PDOs) as a model to study the susceptibility of primary breast cancer cells to EMT.

Developmental eye movement test results of Hebrew-speaking children with cross-linguistic comparisons.

Introduction And Purpose: The developmental eye movement (DEM) test is designed to assess saccadic eye movements and visual-verbal automaticity in children. This study aimed to assess whether there is a need for independent DEM Hebrew norms and to compare DEM results for Hebrew-speaking children with eight other language norms.

Methods: The DEM test was administered to 224 Hebrew-speaking children aged 6-13 years who met the inclusion criteria and read the numbers in Hebrew.

Reducing PTSD in mass medical events: An immediate preventive intervention.

A preventive approach to Post-Traumatic Stress Disorder (PTSD) through an Immediate Psycho-Trauma Intervention (IPTI) may significantly reduce PTSD likelihood and provide a cost-effective way to alleviate suffering. This mixed-method study 1) compared medics who received an IPTI to those who did not after a mass medical event, 2) compared the number medics diagnosed with PTSD from the IPTI group to the minimum number in similar cases reported in the literature. The results indicated that 1.

When to choose intraosseous access in prehospital trauma care: A registry-based study from the Israel Defense Forces.

Purpose: Prompt vascular access is crucial for resuscitating bleeding trauma casualties in prehospital settings but achieving peripheral intravenous (PIV) access can be challenging during hemorrhagic shock due to peripheral vessel collapse. Early intraosseous (IO) device use is suggested as an alternative. This study examines injury characteristics and factors linked to IO access requirements.

A Nationwide, Population-Based Study of Intelligence and Hearing Loss among 3,104,670 Adolescents.

Purpose: Epidemiological studies have demonstrated a relationship between general intelligence (GI) in youth and hearing loss (HL). However, no large-scale study assessed the relations of GI in late adolescence with conductive HL (CHL) and sensorineural HL (SNHL), stratified by severity. This study examined the connection between HL and GI in late adolescence.

The activating receptor NKG2D is an anti-fungal pattern recognition receptor.

NKG2D is a central activating receptor involved in target recognition and killing by Natural Killer and CD8 T cells. The known role of NKG2D is to recognize a family of self-induced stress ligands that are upregulated on stressed cells such as cancerous or virally infected cells. Fungal pathogens are a major threat to human health, infecting more than a billion patients yearly and becoming more common and drug resistant.